Gene Information

Name : cvrA; nhaP2; ycgO (YPTB2497)
Accession : YP_071009.1
Strain : Yersinia pseudotuberculosis IP 32953
Genome accession: NC_006155
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 2946367 - 2948094 bp
Length : 1728 bp
Strand : +
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
TTGGACGCCATCACGATTAATAGCCTTTTTTTGGTCGGCGCAGTGCTGGTGGCAGCCAGTATTTTACTCAGTTCATTTTC
ATCTCGGTTAGGGATCCCTATCCTGGTTATCTTCCTCGCTATCGGAATGTTAGCCGGTACCGACGGGTTGGGCGGAATCG
CGTTTGATAACTATCCGGCCGCTTATTTGGTCAGTAACCTCGCATTAGCCGTGATCCTGTTAGATGGTGGTATGCGGACG
CGGGCCTCATCCTTTCGTGTTGCGCTATGGCCAGCACTTTCCCTGGCGACATTCGGGGTCATCATTACCGCCGGGCTGAC
CGGTCTGGTGGCCGCCTGGCTATTCAACTTAGATATTATTCAGGGCTTATTAATAGGCGCAATTATTGGTTCAACGGATG
CCGCTGCCGTATTCTCTTTATTAGGTGGAAAAGGCCTCAACGAACGTGTCAGCGCTACCCTAGAGATTGAGTCAGGCAGT
AATGATCCAATGGCGGTCTTTTTGACCGTCACGCTGATCGCGATGATTGCCGCGGGTGAAACGAGCCTAAGCTGGATGTT
CTTGGTGCATTTGATCCAACAGTTTGGATTGGGCATCATAATTGGTCTGCTCGGCGGTGGGTTACTGCTGTTGTTAATCA
ACAGAATGGAATTGGCCAACGGCTTATACCCTTTGCTGGCCGTCAGTGGTGGGATTCTAGTGTTTGCTCTTGCGACCGCA
CTGAACGGCAGCGGCATTCTTGCTGTCTATCTCTGTGGATTGTTACTGGGTAACCGCCCTATTCGTAACCGTGCCGGGAT
ATTACAAACTTTCGATGGACTTGCCTGGCTCAGCCAGATTGGCATGTTCCTGGTCTTAGGGTTGCTGCTTAACCCAAGCG
ACCTGTTACCCATCGCCATTCCAGCGCTGCTTTTATCACTATGGATGATTTTGTTCGCCCGGCCACTCTCTGTCTTTATT
GGTCTACTCCCATTTCGTAGCTTCAATCTACGCGAGCGTGTCTTTATCTCGTGGGTTGGCTTACGCGGTGCGGTCCCGGT
TATTCTGGCGGTGTTCCCAATGATGGCGGGCTTGCCCAATGCCAACCTCTTCTTCAATGTGGCCTTCTTCGTCGTGCTGG
TATCACTACTTTTACAGGGTACCACCCTGTCATTTGCTGCCCGCAAAGCAAAATTAGTGGTGCCGCCTACGCTGGCCCCG
GTTTCCCGCATTGGCCTCGATATTGATATGAACAATCAATGGGAACAGTTTATTTATCAGCTTAGTTGCGATAAATGGTG
TATTGGTGCCACGTTGCGCGATTTAAAAATGCCACAAGGAACACGTATCGCCGCCCTGTTCCGTGGCAAAGATTTATTGC
ACCCCACCGGTAGCACCCGCCTAAAAGAAGGCGATATCTTGTGTGTTATCGGTCAGGAGCATGACTTACCGGCGCTAGGT
AAACTGTTCAGCCAATCACCCAACATCCAATTGGATGAACGTTTCTTCGGTGATTTTATTCTTGATGCGGATGCTAAACT
CCAAGATATTTCACAGATTTATGGTCTTAATCTGGAGCCTACCGTTGATAAACAACAAACTTTGGGTCAATTTGTTTTAT
ACCTCTTTGGCGGGGAACCCGTTATTGGTGACCAAATTGAGTGGGACGGTCTGACCTGGACGATTGCCGAAATGGAATCA
GATCGTGTCAGCCGGGTTGGCGTTAAGATCGTTACCGATAAGGCGTAA

Protein sequence :
MDAITINSLFLVGAVLVAASILLSSFSSRLGIPILVIFLAIGMLAGTDGLGGIAFDNYPAAYLVSNLALAVILLDGGMRT
RASSFRVALWPALSLATFGVIITAGLTGLVAAWLFNLDIIQGLLIGAIIGSTDAAAVFSLLGGKGLNERVSATLEIESGS
NDPMAVFLTVTLIAMIAAGETSLSWMFLVHLIQQFGLGIIIGLLGGGLLLLLINRMELANGLYPLLAVSGGILVFALATA
LNGSGILAVYLCGLLLGNRPIRNRAGILQTFDGLAWLSQIGMFLVLGLLLNPSDLLPIAIPALLLSLWMILFARPLSVFI
GLLPFRSFNLRERVFISWVGLRGAVPVILAVFPMMAGLPNANLFFNVAFFVVLVSLLLQGTTLSFAARKAKLVVPPTLAP
VSRIGLDIDMNNQWEQFIYQLSCDKWCIGATLRDLKMPQGTRIAALFRGKDLLHPTGSTRLKEGDILCVIGQEHDLPALG
KLFSQSPNIQLDERFFGDFILDADAKLQDISQIYGLNLEPTVDKQQTLGQFVLYLFGGEPVIGDQIEWDGLTWTIAEMES
DRVSRVGVKIVTDKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 4e-152 76
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 4e-152 76