Gene Information

Name : yfeA (YPTB2347)
Accession : YP_070862.1
Strain : Yersinia pseudotuberculosis IP 32953
Genome accession: NC_006155
Putative virulence/resistance : Virulence
Product : iron siderophore-ABC transporter substrate-binding protein YfeA
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0803
EC number : -
Position : 2768745 - 2769713 bp
Length : 969 bp
Strand : +
Note : similar to Yersinia pestis YPO2439 yfeA; periplasmic-binding protein (100% evalue=0); Pasteurella multocida PM0400 yfeA; Mn transport protein ABC transporter, iron (chelated) transporter, periplasmic-binding protein, (76.9% evalue=1.E-122); Citation: Bear

DNA sequence :
ATGTTAATTAAGAAAAAAAGTCCTTATCTCAAAATGATAGAACGACTAAACTCCCCTTTTCTACGGGCTGCAGCCTTGTT
TACAATTGTCGCATTCTCATCGCTGATCAGTACCGCTGCTTTAGCAGAAAATAATCCCAGCGATACAGCCAAAAAATTCA
AAGTTGTGACTACATTCACAATCATTCAGGATATTGCACAAAATATCGCCGGTGATGTTGCCGTGGTGGAGTCAATAACC
AAGCCAGGCGCAGAGATTCATGACTATCAACCTACCCCACGAGATATTGTAAAAGCACAGTCAGCAGACCTTATCTTATG
GAATGGCATGAATCTGGAGCGTTGGTTTGAGAAGTTCTTCGAAAGTATTAAAGATGTCCCGTCTGCCGTCGTGACCGCAG
GTATTACACCCCTGCCTATCCGTGAAGGCCCCTATAGCGGCATTGCCAACCCACATGCCTGGATGTCGCCATCAAATGCG
CTAATATATATTGAGAATATCCGCAAAGCGTTAGTTGAACACGATCCCGCTCATGCAGAAACCTATAACCGTAACGCGCA
AGCCTATGCTGAAAAAATTAAGGCGCTAGATGCTCCACTGCGTGAGCGTTTATCTCGTATTCCTGCGGAACAGCGTTGGT
TAGTAACCAGTGAAGGGGCATTTAGTTATCTTGCCAAAGACTATGGTTTTAAAGAGGTTTACTTATGGCCAATCAATGCA
GAGCAACAAGGTATTCCGCAACAAGTTAGACACGTGATTGATATTATTCGCGAAAATAAAATTCCGGTGGTGTTTAGTGA
GAGTACTATTTCCGACAAACCCGCCAAACAAGTGAGTAAAGAAACCGGTGCACAATATGGCGGCGTGCTATATGTTGATT
CTCTGTCGGGCGAAAAAGGCCCGGTCCCCACTTACATCAGTTTAATTAACATGACTGTAGATACTATCGCTAAAGGATTC
GGTCAATGA

Protein sequence :
MLIKKKSPYLKMIERLNSPFLRAAALFTIVAFSSLISTAALAENNPSDTAKKFKVVTTFTIIQDIAQNIAGDVAVVESIT
KPGAEIHDYQPTPRDIVKAQSADLILWNGMNLERWFEKFFESIKDVPSAVVTAGITPLPIREGPYSGIANPHAWMSPSNA
LIYIENIRKALVEHDPAHAETYNRNAQAYAEKIKALDAPLRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPINA
EQQGIPQQVRHVIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEKGPVPTYISLINMTVDTIAKGF
GQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitA YP_217781.1 iron transporter: fur regulated Virulence SPI-1 Protein 5e-84 63
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein Virulence SPI-1 Protein 4e-84 63
sitA NP_806464.1 iron transporter periplasmic-binding protein Virulence SPI-1 Protein 4e-84 63
sitA NP_461782.1 periplasmic binding protein Virulence SPI-1 Protein 4e-84 63
sitA AAD41065.1 SitA Virulence centisome 63 pathogenicity island Protein 3e-84 63

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yfeA YP_070862.1 iron siderophore-ABC transporter substrate-binding protein YfeA BAC0439 Protein 3e-135 100
yfeA YP_070862.1 iron siderophore-ABC transporter substrate-binding protein YfeA BAC0349 Protein 2e-84 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yfeA YP_070862.1 iron siderophore-ABC transporter substrate-binding protein YfeA VFG0525 Protein 2e-84 63