Gene Information

Name : qacE (YPTB2252)
Accession : YP_070767.1
Strain : Yersinia pseudotuberculosis IP 32953
Genome accession: NC_006155
Putative virulence/resistance : Resistance
Product : DMT superfamily multiple drug efflux pump
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2076
EC number : -
Position : 2658626 - 2658964 bp
Length : 339 bp
Strand : -
Note : similar to Yersinia pestis YPO2333 qacE; quaternary ammonium compound-resistance protein (100% evalue=1.E-56); Brucella melitensis BMEI1045 quateRNAry ammonium compound-resistance protein qacE (55.4% evalue=3.E-30)

DNA sequence :
ATGATAATGAGCAGTTTTGTCTATTTATTTATGGCGATTATTGCCGAAGTAGTTGCAACGACGATGCTAAAAGCATCCGA
TGGTTTTTCTCGATTAGTCCCTTCAGTGGTGGTCGTGATTGGTTATGGTATTGCTTTTTGGGGGCTTTCGCAGGTAGTCA
AAACCATGCCGCTGGGTATTGCTTATGCGATTTGGTCCGGTTTGGGGATTGTACTGGTCTCAATCGCTGCCACCTTTATG
TATCAACAAAAGCTGGATTGGGCGGCGGTTGTCGGTATGGCGCTGATTATTTCGGGTGTTATGGTGATTAACCTCCTGTC
CAAGACACCGATGCATTAA

Protein sequence :
MIMSSFVYLFMAIIAEVVATTMLKASDGFSRLVPSVVVVIGYGIAFWGLSQVVKTMPLGIAYAIWSGLGIVLVSIAATFM
YQQKLDWAAVVGMALIISGVMVINLLSKTPMH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
qacEdelta1 AGK06970.1 QacEdelta1 Not tested SGI1 Protein 9e-19 51
qacE-delta1 ACY75523.1 QacE-delta1 Not tested Tn6060 Protein 9e-19 51
qacEdelta1 AAK02056.1 quaternary ammonium compound and disinfectant protein Not tested SGI1 Protein 9e-19 51
qacEdelta1 AGK06979.1 QacEdelta1 Not tested SGI1 Protein 9e-19 51
qacE-delta1 ACY75532.1 QacE-delta1 Not tested Tn6060 Protein 9e-19 51
qacEdelta1 ABB48428.1 QacEdelta1 Not tested SGI1 Protein 9e-19 51
ACICU_00227 YP_001844886.1 membrane transporter Not tested AbaR20 Protein 1e-18 51
qacEdelta1 AGK07016.1 QacEdelta1 Not tested SGI1 Protein 9e-19 51
qacE-delta1 AET25389.1 QacE-delta1 Not tested PAGI-2(C) Protein 9e-19 51
qacEdelta1 ABZ01839.1 QacEdelta1 Not tested SGI2 Protein 9e-19 51
qacEdelta1 YP_005797134.1 quaternary ammonium compound-resistance protein Not tested AbaR4e Protein 1e-18 51
qacEdelta1 AGK07074.1 QacEdelta1 Not tested SGI1 Protein 9e-19 51
qacE-delta1 AFG30112.1 QacE-delta1 Not tested PAGI-2 Protein 9e-19 51
qacEdelta1 CAJ77030.1 Quaternary ammonium compound-resistance protein Not tested AbaR1 Protein 9e-19 51
qacEdelta1 YP_005797150.1 quaternary ammonium compound-resistance protein Not tested AbaR4e Protein 1e-18 51
qacEdelta1 AGK07100.1 QacEdelta1 Not tested SGI1 Protein 9e-19 51
qacEdelta1 AGF34989.1 QacEdelta1 Not tested SGI1 Protein 9e-19 51
qacEdelta1 CAJ77049.1 Quaternary ammonium compound-resistance protein Not tested AbaR1 Protein 9e-19 51
ebr YP_006098377.1 putative ethidium bromide resistance protein Not tested Tn2411 Protein 1e-18 51
qacEdelta1 AGK07109.1 QacEdelta1 Not tested SGI1 Protein 9e-19 51
qacEdelta1 AGF35028.1 QacEdelta1 Not tested SGI1 Protein 9e-19 51
qacEdelta1 CAJ77052.1 Quaternary ammonium compound-resistance protein Not tested AbaR1 Protein 9e-19 51
qacEdelta1 ACN81026.1 QacEdelta1 Not tested AbaR5 Protein 1e-18 51
qacEdelta1 AFV53123.1 QacEdelta1 multidrug exporter Not tested AbGRI2-1 Protein 9e-19 51
qacEdelta1 AGF35063.1 QacEdelta1 Not tested SGI1 Protein 9e-19 51
qacEdelta1 CAJ77088.1 Quaternary ammonium compound-resistance protein Not tested AbaR1 Protein 9e-19 51
qacEdelta1 AGK36647.1 QacEdelta1 Not tested AbaR26 Protein 9e-19 51
qacEdelta1 AGK06933.1 QacEdelta1 Not tested SGI1 Protein 9e-19 51
qacE-deltal ACF06159.1 quartenary ammonium compound resistance protein Not tested Tn5036-like Protein 9e-19 51
qacEdelta1 AAK02047.1 quaternary ammonium compound and disinfectant protein Not tested SGI1 Protein 9e-19 51
unnamed CAD42067.1 hypothetical protein Not tested PAI II 536 Protein 7e-16 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
qacE YP_070767.1 DMT superfamily multiple drug efflux pump BAC0377 Protein 5e-37 76
qacE YP_070767.1 DMT superfamily multiple drug efflux pump CP004022.1.gene1549. Protein 8e-35 73
qacE YP_070767.1 DMT superfamily multiple drug efflux pump BAC0324 Protein 5e-22 58
qacE YP_070767.1 DMT superfamily multiple drug efflux pump BAC0322 Protein 5e-23 55
qacE YP_070767.1 DMT superfamily multiple drug efflux pump CP001138.1.gene1489. Protein 1e-23 55
qacE YP_070767.1 DMT superfamily multiple drug efflux pump NC_002695.1.913273.p Protein 3e-21 53
qacE YP_070767.1 DMT superfamily multiple drug efflux pump NC_010410.6003348.p0 Protein 2e-20 52
qacE YP_070767.1 DMT superfamily multiple drug efflux pump BAC0002 Protein 2e-20 52
qacE YP_070767.1 DMT superfamily multiple drug efflux pump BAC0150 Protein 4e-21 51
qacE YP_070767.1 DMT superfamily multiple drug efflux pump BAC0323 Protein 4e-19 51
qacE YP_070767.1 DMT superfamily multiple drug efflux pump BAC0329 Protein 3e-16 44
qacE YP_070767.1 DMT superfamily multiple drug efflux pump BAC0192 Protein 3e-14 43
qacE YP_070767.1 DMT superfamily multiple drug efflux pump BAC0140 Protein 6e-12 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
qacE YP_070767.1 DMT superfamily multiple drug efflux pump VFG1586 Protein 3e-16 41