Gene Information

Name : YPTB2197 (YPTB2197)
Accession : YP_070714.1
Strain : Yersinia pseudotuberculosis IP 32953
Genome accession: NC_006155
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 2587156 - 2588676 bp
Length : 1521 bp
Strand : +
Note : similar to Pseudomonas aeruginosa PA4022 probable aldehyde dehydrogenase (79.2% evalue=0); Pseudomonas aeruginosa PA1984 probable aldehyde dehydrogenase (78.6% evalue=0)

DNA sequence :
ATGCGTTATGCACATCCAGGAACACCAGAAGCTTTAGTCTCTTTCAAAGCAACCTATGGCAACTATATTGGTGGGGAATT
CGTTGAACCGCTCGGCGGTCAGTACTTTATGAATACTTCGCCAGTGAATGGCAGTGATATTGCGCAGTTCCCACGTTCCG
ACGCCCGAGACATCGACGCAGCGTTAGATGCCGCCCATCGAGCCGCTGACGCTTGGGGGAAAACCAGTGTTCAACATCGT
TCCAACCTCCTGCTACAAATGGCTGATCGTATCGAAGCCAATCTTGAATACCTTGCCGTGGCAGAAAGTTGGGATAACGG
AAAGCCGATTCGTGAAACACTGAACGCCGACCTGCCACTTGCGGTGGATCATTTCCGCTATTTTGCCGGGTGCCTGCGGG
CACAGGAAGGCGGTGTGGCAGAAATTGATGAGAAGACCGTTGCCTACCACTTTCATGAACCGCTAGGTGTGGTAGGGCAA
ATTATCCCATGGAACTTCCCGCTGCTAATGGCCGCGTGGAAACTCGCGCCCGCACTGGCTGCGGGTAACTGTGTGGTCCT
GAAACCAGCAGAGCAGACACCACTGGGAATAACACTGTTACTGGAGTTAGTCGGTGATCTCTTCCCAGCAGGTGTGCTCA
ATGTAGTTCAGGGCTACGGCCGTGAAGCAGGAGAAGCGTTGGCGAGTAGTAAACGTATTGCCAAAATTGCTTTTACTGGC
TCAACGCCGGTGGGTCGCCACATCATGGCTTGTGCTGCGGAGAATATTATTCCCTGTACTGTCGAACTGGGTGGCAAGTC
ACCGAACATCTATTTTGCCGATGTGATGGAGGCAGAACCCGAGTTCATTGAGAAAGCGGTTGAAGGACTCGTCTTGGGCT
TCTTCAATCAGGGAGAAGTTTGTACCTGTCCTTCTCGTGCGCTGATCCATGAATCGATTTACGCACCATTTATGGCGCGA
GTCATGGCAAAGGTCGCCAATATTCGCCGTGGCGATCCACTAGATACCGAAACCATGATTGGTGCTCAGGCTTCCCGTCA
ACAGTTTGACAAAATCCTTTCCTATATTGACATCGCCCGTAAAGAAGGGGGGGAAATCCTCACGGGGGGCGCACGGGCAA
CTATGACACCTGCGCTGGATGCCGGTTTCTACATCCAGCCGACATTGATTAAAGGTGATAATCTGATGCGCTGCTTCCAA
GAAGAAATTTTTGGCCCAGTAATCGGTGTAACCACGTTTAAAGATGAAGCTGAAGCACTGGCTATTGCAAATCAGACGCA
ATTTGGCCTTGGTGCGGGTATCTGGACGCGTGATACCCATCTGGCTTATCGCATGGGTAGAGGCATTAAAGCGGGTCGTG
TCTGGACGAACTGCTATCATGTCTATCCTGCGCATGCTGCATTTGGCGGCTATAAACAGTCGGGCGTAGGGCGTGAAACA
CATAAAATGGCATTGAACCAGTATCAACAAACGAAGAACTTGTTGGTCAGCTATGACACCGCGCCTTTAGGGTTGTTTTG
A

Protein sequence :
MRYAHPGTPEALVSFKATYGNYIGGEFVEPLGGQYFMNTSPVNGSDIAQFPRSDARDIDAALDAAHRAADAWGKTSVQHR
SNLLLQMADRIEANLEYLAVAESWDNGKPIRETLNADLPLAVDHFRYFAGCLRAQEGGVAEIDEKTVAYHFHEPLGVVGQ
IIPWNFPLLMAAWKLAPALAAGNCVVLKPAEQTPLGITLLLELVGDLFPAGVLNVVQGYGREAGEALASSKRIAKIAFTG
STPVGRHIMACAAENIIPCTVELGGKSPNIYFADVMEAEPEFIEKAVEGLVLGFFNQGEVCTCPSRALIHESIYAPFMAR
VMAKVANIRRGDPLDTETMIGAQASRQQFDKILSYIDIARKEGGEILTGGARATMTPALDAGFYIQPTLIKGDNLMRCFQ
EEIFGPVIGVTTFKDEAEALAIANQTQFGLGAGIWTRDTHLAYRMGRGIKAGRVWTNCYHVYPAHAAFGGYKQSGVGRET
HKMALNQYQQTKNLLVSYDTAPLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-146 64
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-153 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-153 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-153 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-152 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPTB2197 YP_070714.1 aldehyde dehydrogenase VFG0082 Protein 3e-146 64