Gene Information

Name : topB (YPTB2091)
Accession : YP_070608.1
Strain : Yersinia pseudotuberculosis IP 32953
Genome accession: NC_006155
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 2462367 - 2464295 bp
Length : 1929 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGATGCGACTGTTTATTGCCGAAAAACCCAGTTTAGCGCGAGCGATTGCAGATATTTTGCCAAAACCGCATCGTCGAGG
TGGTGGATTCATCGCCTGTGGTAATGATCAAATGGTGACCTGGTGTGTTGGTCATTTACTCGAACAAGCCCAGCCGGATG
CTTATGACAGCCGTTATGCACGTTGGTCATTAGCGGACTTACCGATCATTCCTGAAAAATGGCAGCTACAACCTCGTCCT
TCCGTCAGCAAACAACTCAATGTGATTAAGCAACTGTTACAGCAAGCCGATGAAGTGGTCCATGCTGGCGACCCGGATAG
AGAAGGGCAACTGTTAGTTGATGAGGTGCTGGATTATTTGGGATTGGCCGCAGAGAAACGGCAAAATGTTCGTCGTTGCT
TGATTAACGATTTAAACCCACAGGCGGTTGAGCGTGCAGTGGAGCGCTTGCGTTATAACCGCGAGTTTATCCCGCTGTGT
GTTTCTGCGTTGGCTCGAGCCAGAGCCGATTGGCTCTATGGCATCAATATGACTCGCGCCTATACCATTCTTGGGCGCAA
TGCGGGCTATGACGGTGTTTTATCCGTCGGGCGGGTACAAACGCCCGTATTGGGGCTGGTTGTTCGCCGTGATGAAGAGA
TTGAAAGCTTCATTCCCAAAGATTTTTTTGAAGTTAAAGCCCACATAGTGACGCCTGCAGACGAACGTTTTATTGCTCTC
TGGCAGCCGAGTGACTCCTGCGAATCTTATCAGGACGAAGAAGGGCGCTTGTTGCATCGGCCGCTTGCAGAACATGTTGT
CAATCGCATAACCGGCCAGCCCGCGCTGGTGACATCCTATAATGATAAACGGGAATCGGAAACGGCACCGTTGCCATTCT
CCTTGTCTACATTACAAATCGAAGCTGCAAAACGTTTCGGCCTCAGTGCTCAGCAAGTATTGGATATTTGCCAACGGTTG
TATGAAACGCACAAATTGATTACGTATCCGCGCTCGGATTGCCGATATCTACCTGAAGAGCATTTTGCCGGGCGTCATTC
GGTGCTTAATGCCATTAGTCTTCATCAGTCAGACCTTTTGCCGCTTGAGGTCATGGATAGTGATCGGCGCAACCGCTGCT
GGGATGATAAAAAAGTCGATGCGCACCACGCTATTATCCCAACCGCACGTGCCAGCAAAGTGAATTTGACGACGGATGAA
GGCAAAGTATACCGGTTGGTGGCACAGCAATATCTGATGCAATTCTGTCCAGATGCACAGTTCCGTAAGTGTGTGATTGA
ATTGGATATCGCTGGCGGGAAATTTATTGCCAAGGCACGCTTTTTGGCCGAGGCGGGATGGCGGACCTTACTGGGCAGTA
AAGAGCGTGATGAAGAGAACGAAGGTGCGCCATTGCCGGTGGTAGCCAAAGGGGCTGAATTATTATGTGAACGCGGTGAG
GTTGTTGAACGACAAACTCAGCCACCCCGGCCTTTCACCGACGCCAGTTTATTATCGGCGATGACAGGAATTGCGCGTTT
CGTACAGGATAAAGAACTGAAAAAAGTTTTGCGAGCCACCGATGGCTTGGGTACGGAAGCCACTCGAGCAGGTATTATCG
AACTGCTCTTCAAGCGCACTTTTCTCTTTAAGAAAGGGCGTTATATACATGCCAGCCCTGCGGGACGCGCGTTGATTCAT
GCATTACCGGATATTGCGGCACGGCCAGATATGACAGCACATTGGGAATCAACGTTGACACAAATCAGTGAAAAAAACTG
CCGCTATCAAGATTTTATGCAACCACTGGTGATGACATTGCAGGATTTAATTAGTCAGGCGAAACAAAATCGTTCTCCAC
AGGTTTTCCGTGGGTTACCCGCCGGCCCTTCAGGGGCACCCAAGAAACGTAAAAAAATATCGTCTAAGGCCAAGGAGAGT
AAATCATGA

Protein sequence :
MMRLFIAEKPSLARAIADILPKPHRRGGGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYARWSLADLPIIPEKWQLQPRP
SVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLGLAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLC
VSALARARADWLYGINMTRAYTILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIAL
WQPSDSCESYQDEEGRLLHRPLAEHVVNRITGQPALVTSYNDKRESETAPLPFSLSTLQIEAAKRFGLSAQQVLDICQRL
YETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLLPLEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDE
GKVYRLVAQQYLMQFCPDAQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDEENEGAPLPVVAKGAELLCERGE
VVERQTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAGIIELLFKRTFLFKKGRYIHASPAGRALIH
ALPDIAARPDMTAHWESTLTQISEKNCRYQDFMQPLVMTLQDLISQAKQNRSPQVFRGLPAGPSGAPKKRKKISSKAKES
KS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 3e-107 41
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 2e-107 41
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 4e-103 41