Gene Information

Name : copR (YPTB1993)
Accession : YP_070510.1
Strain : Yersinia pseudotuberculosis IP 32953
Genome accession: NC_006155
Putative virulence/resistance : Virulence
Product : transcriptional activator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2349245 - 2349937 bp
Length : 693 bp
Strand : -
Note : similar to Yersinia pestis YPO2001 copR; transcriptional activator (99.5% evalue=1.E-124); Pseudomonas aeruginosa PA1437 probable two-component response regulator (66% evalue=3.E-76)

DNA sequence : 
ATGCGGCTATTGTTGGTAGAAGATGAGGAGAAGACATCTTCGTATATCAATCGCGCCCTCAGCGAGTTGGGCTTTACCGT
CGATGTGGCGGCCACCGGGAACGACGGATTATATCTGGCTCTTGAGTATGATTACGATACGATTGTGCTCGATGTCATGT
TGCCCGGCATGGATGGTTACAGCGTTCTCGAAGGCCTACGCGCCAGCAAACAAACTCCGGTTCTGATGTTATCCGCCCGT
GGCTCGGTTGATGAACGAGTTAAGGGCCTGCGTCACGGTGCCGACGATTATTTGCCTAAGCCTTTTTCGCTGATTGAACT
GGTTGCGCGTATCCAGGCGTTGTTGAGGCGGCGTCCCAGTGATGGTGTAGATGTCAGCCAATTGCACATTAATGATCTAC
ATCTCGACCTGCTGGCAAGGCGTGTCACGCGAGCCGGTGAACGTCTTGAACTCACCGCCAAAGAGTTCGCCCTGTTAAGC
CTGTTAGCCAGACATCAGGGAGAAATTCTGTCAAAAATGATGATTGCAGAGCAGGTCTGGGACATGAATTTTGACAGCGA
TGCTAATGTCGTTGAGGTGGCGATAAAACGCCTGCGGGCGAAAATAGATACGCCCTACCCGGTCAAACTGCTGCATACAG
TGCGAGGCATGGGGTATGTCCTTGAAACTCGCCCCGATCGCCAGACTAAATAG

Protein sequence : 
MRLLLVEDEEKTSSYINRALSELGFTVDVAATGNDGLYLALEYDYDTIVLDVMLPGMDGYSVLEGLRASKQTPVLMLSAR
GSVDERVKGLRHGADDYLPKPFSLIELVARIQALLRRRPSDGVDVSQLHINDLHLDLLARRVTRAGERLELTAKEFALLS
LLARHQGEILSKMMIAEQVWDMNFDSDANVVEVAIKRLRAKIDTPYPVKLLHTVRGMGYVLETRPDRQTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 4e-54 50
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 7e-53 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
copR YP_070510.1 transcriptional activator BAC0083 Protein 1e-62 61
copR YP_070510.1 transcriptional activator BAC0197 Protein 2e-59 58
copR YP_070510.1 transcriptional activator BAC0638 Protein 3e-53 57
copR YP_070510.1 transcriptional activator BAC0125 Protein 3e-61 56
copR YP_070510.1 transcriptional activator BAC0111 Protein 4e-59 54
copR YP_070510.1 transcriptional activator BAC0347 Protein 3e-52 51
copR YP_070510.1 transcriptional activator BAC0308 Protein 1e-52 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
copR YP_070510.1 transcriptional activator VFG0596 Protein 2e-54 50
copR YP_070510.1 transcriptional activator VFG1389 Protein 2e-38 48
copR YP_070510.1 transcriptional activator VFG1390 Protein 1e-39 44
copR YP_070510.1 transcriptional activator VFG1386 Protein 4e-35 43