Gene Information

Name : hemC (YPTB0184)
Accession : YP_068731.1
Strain : Yersinia pseudotuberculosis IP 32953
Genome accession: NC_006155
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 221351 - 222292 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTTAGACAAAATTATTCGAATTGCCACACGACAAAGCCCGCTCGCCTTATGGCAAGCACATTATGTTCAACATTTATT
GCAAGCCAATCACCCTGGTCTGCAAATCGAACTGGTCCCAATGGTCACCCGTGGGGATATCATTTTGGATACACCATTGG
CCAAAGTCGGTGGTAAGGGTTTATTTGTCAAAGAATTAGAGCTGGCGCTGCTGGACGGCAGAGCTGATATTGCCGTGCAT
TCGATGAAAGATGTGCCCATCGCTTTCCCCGAAGGGCTGGGTTTAGTCGCGATTTGTGAACGTGAAGACCCGCGTGATGC
TTTCGTCTCGTCACATTATGCCCATCTGGATGATCTCCCTGCAGGCAGTGTTGTCGGTACCTCCAGCCTGCGCCGCCAGT
GTCAGCTACGCGAACGGCGACCAGACCTGATTATCCGCGATCTACGGGGTAACGTCGGTACCCGCCTTGCCAAACTGGAT
AATGGTGACTATCAGGCCATTATTCTGGCTGTCGCGGGTCTCAAGCGCCTCGGTCTGGAAACCCGAATTCGCTATGCCAT
GTCAGCGGAGGAGTCCCTGCCTGCTGTCGGCCAAGGTGCCGTAGGTATCGAATGCCGTCTGGATGATGACCATACCCGCC
AGTTGCTGGCTCCGTTGAACCATCGGCACACCGAATTACGGGTCTGTGCGGAGCGGGCAATGAATATTCGCCTTGAAGGG
GGTTGCCAAGTCCCGATCGGTAGCTACGCTGAACTGGAAGGTGATACTTTATGGCTACGGGCGCTGGTGGGAGCACCTGA
TGGCAGCCAAATGATCCGGGGTGAACGCCGTGGTCCGGCGGCAGAGGCTGAGCAGATGGGCATTGAACTTGCCGATGAGT
TGCTATCACGCGGCGCACGAGAAATCCTGGCGGCGGTTTATCTGGATAATCCTGCGCGATGA

Protein sequence :
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKGLFVKELELALLDGRADIAVH
SMKDVPIAFPEGLGLVAICEREDPRDAFVSSHYAHLDDLPAGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLD
NGDYQAIILAVAGLKRLGLETRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAREILAAVYLDNPAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 7e-83 62
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 7e-83 62