Gene Information

Name : fliI (YPTB1700)
Accession : YP_070227.1
Strain : Yersinia pseudotuberculosis IP 32953
Genome accession: NC_006155
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 2053705 - 2055105 bp
Length : 1401 bp
Strand : -
Note : involved in type III protein export during flagellum assembly

DNA sequence :
ATGACCCCCCGCCTCAGCCGCTGGCTTACCTCTTTAGATAAATTCGAAGAGCGTATCAGCCAAACGACAACAATCCGCCG
TTATGGCCGCTTGACCCGCGCCACCGGTTTAGTGCTGGAAGCCACTGGTCTGCAATTGCCGTTAGGGGCGACCTGTCTGA
TTGAGCGCCATAATGGCGGTGAAGTGCAGGAAGTCGAAAGCGAAGTGGTTGGTTTTAACGGTCAGCATCTGTTTCTTATG
CCTTTGGAAGATGTGGAAGGTATCGTCCCCGGTGCCAGAGTGTATGCCCGAGTCACCACCAGCGGCACGTCTGCTAGTAA
ACAATCAATTCCCAGTAAACAATCATTCGCCAGTAAACAATTACCCCTTGGCCCCGAGTTATTGGGCCGGGTATTGGATG
GCAGTGCCAAACCGCTTGATGGCTTACCGGCACCTGAAACCGGTTATCGTGCACCACTGATTACACCACCGATAAACCCT
TTGCAACGCACCGCCATTGTCCAAGTCTTGGATGTGGGCGTGCGTACCATTAACGCCTTGTTGACGGTCGGGCGCGGCCA
GCGGATGGGGCTGTTTGCTGGCTCTGGGGTTGGCAAAAGCGTACTGCTCGGCATGATGGCCCGTTACACACAGGCTGACG
TGATCGTGGTTGGGCTGATTGGTGAGCGTGGCCGTGAAGTCAAAGATTTTATCGAAAATATTCTCGGGGCTGAAGGCCGC
GCCCGTTCGGTGGTTATCGCCGCGCCAGCCGATGTGTCACCGTTGCTGCGTATGCAAGGTGCCGCCTATGCCACCCGTAT
TGCCGAAGATTTCCGCGATCGTGGTCAGCATGTGTTGCTAATTATGGACTCCCTAACCCGCTATGCCATGGCGCAACGTG
AAATCGCGCTGGCTATCGGCGAGCCTCCCGCGACCAAAGGCTACCCGCCCTCCGTCTTCGCCAAATTACCGGCACTGGTT
GAACGGGCGGGTAACGGTGTTTCAGGCGGCGGCTCCATTACCGCATTTTATACCGTCCTCACCGAAGGTGATGATCAGCA
AGATCCTATTGCTGACTCTGCGCGCGCCATCCTCGATGGCCATGTGGTGCTATCTCGCCGTTTGGCTGAATCCGGTCACT
ATCCGGCTATCGATATCGAAGCCTCTATCAGCCGTGCCATGACCTCGTTAATCGATGATGACCATTACAGCCGGGTGCGC
CAGTTTAAACAACTGCTTGCCAGTTATCAGCGTAACCGCGATTTGGTCAGTGTCGGGGCTTATGCTGCGGGCAGTGATCC
CTTATTGGACAAAGCGATTGCCCTGTACCCGCAGATGGAGGCTTTCTTGCAGCAAGGCATGTTTGAGCGCAGCAGTTTTG
ACGATGCCTGCCAGCATTTGAAGGGTTTATTTCCCGGCTAA

Protein sequence :
MTPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLEATGLQLPLGATCLIERHNGGEVQEVESEVVGFNGQHLFLM
PLEDVEGIVPGARVYARVTTSGTSASKQSIPSKQSFASKQLPLGPELLGRVLDGSAKPLDGLPAPETGYRAPLITPPINP
LQRTAIVQVLDVGVRTINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADVIVVGLIGERGREVKDFIENILGAEGR
ARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPALV
ERAGNGVSGGGSITAFYTVLTEGDDQQDPIADSARAILDGHVVLSRRLAESGHYPAIDIEASISRAMTSLIDDDHYSRVR
QFKQLLASYQRNRDLVSVGAYAAGSDPLLDKAIALYPQMEAFLQQGMFERSSFDDACQHLKGLFPG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-79 53
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-68 49
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 4e-68 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 4e-68 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-68 49
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 5e-66 48
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-68 47
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-71 47
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-71 47
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-78 46
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-77 46
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-78 46
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 5e-78 46
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 5e-78 46
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-77 46
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-77 46
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-74 45
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-74 45
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-71 44
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 3e-69 44
escN AAK26715.1 EscN Virulence LEE Protein 3e-69 44
escN AAL57542.1 EscN Virulence LEE Protein 3e-69 44
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-69 44
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-68 44
escN AAC38383.1 EscN Virulence LEE Protein 1e-68 43
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-68 43
escN AAC31513.1 L0034 Virulence LEE Protein 8e-69 43
escN YP_003223475.1 translocator EscN Virulence LEE Protein 6e-69 43
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 8e-69 43
escN YP_003236088.1 translocator EscN Virulence LEE Protein 5e-69 43
escN CAI43874.1 EscN protein Virulence LEE Protein 4e-69 43
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-68 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-58 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 6e-58 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-58 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-58 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-58 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-73 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-56 42
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 5e-64 41
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-69 41
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-55 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_070227.1 flagellum-specific ATP synthase VFG2331 Protein 0.0 94
fliI YP_070227.1 flagellum-specific ATP synthase VFG2499 Protein 6e-145 69
fliI YP_070227.1 flagellum-specific ATP synthase VFG1254 Protein 7e-120 59
fliI YP_070227.1 flagellum-specific ATP synthase VFG0515 Protein 2e-68 49
fliI YP_070227.1 flagellum-specific ATP synthase VFG0048 Protein 3e-76 46
fliI YP_070227.1 flagellum-specific ATP synthase VFG2459 Protein 4e-58 45
fliI YP_070227.1 flagellum-specific ATP synthase VFG0192 Protein 5e-79 44
fliI YP_070227.1 flagellum-specific ATP synthase VFG1008 Protein 2e-59 44
fliI YP_070227.1 flagellum-specific ATP synthase VFG0390 Protein 4e-74 43
fliI YP_070227.1 flagellum-specific ATP synthase VFG2144 Protein 5e-81 43
fliI YP_070227.1 flagellum-specific ATP synthase VFG0730 Protein 8e-69 43
fliI YP_070227.1 flagellum-specific ATP synthase VFG0812 Protein 4e-69 43
fliI YP_070227.1 flagellum-specific ATP synthase VFG0555 Protein 2e-58 43
fliI YP_070227.1 flagellum-specific ATP synthase VFG1778 Protein 2e-56 41