Gene Information

Name : hpaE (YPTB1639)
Accession : YP_070166.1
Strain : Yersinia pseudotuberculosis IP 32953
Genome accession: NC_006155
Putative virulence/resistance : Unknown
Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.60
Position : 1990282 - 1991748 bp
Length : 1467 bp
Strand : +
Note : similar to Yersinia pestis YPO1763 hpaE; 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase (95% evalue=0); Salmonella typhimurium STM1102 hpaE; 4-hydroxyphenylacetate catabolism (84% evalue=0)

DNA sequence :
ATGAAGATCGTTAACCATTGGATTGATGGGAAAAATATTACCAGTAAGGACTATTTCACAACAATCAACCCGGCCACTGG
CGAGGTGCTGGCTGACGTGGCAAGCGGGGGGATAAAAGAGATCAACCAAGCCGTTGCTGCCGCGAAAAGTGCTTTCCCTC
ACTGGGCTAACCTGCCGATGAAAGTGCGTGCCCGTCTAATGCGCCGTCTGGGGGAGTTGATTGAGCAACAGATCCCAGAA
ATAGCGCAGATGGAAACGCAGGATACCGGCCTGCCCATTTATCAAACGCAAAATGCCTTGATCCCGCGGGCAGCACATAA
CTTCGAATTTTTTGCCGAAATTTGTCAGCAAATGAATGGCCAGACGTATCCGGTTGACGATCAAATGTTGAATTACACCT
TGGTGCAACCCGTGGGAGTGTGTGCGTTGGTCTCCCCTTGGAATGTCCCTTTTATGACGGCGACCTGGAAGGTCGCGCCT
TGTTTGGCGCTGGGTAACACCGCGATATTGAAAATGTCGGAGCTATCGCCACTGACCGCAGACAAACTGGGTGAACTGGC
CTTAGAGGCGGGTATACCGGCGGGGGTTCTCAACGTGGTACAAGGATATGGGGCCACTGTCGGTGATGCATTGGTATGTC
ATCAGGATGTCCGAGCTATCTCTTTTACCGGCGGCACCGCGACGGGAAACCGCATCATGCAACGTGCCGGGTTGAAAAAA
TACTCCATGGAACTCGGTGGTAAATCCCCGGTACTTATCTTCGACGATGCTGATATCGAACGGGCTATGGATGCGGCGCT
ATTTTCCATCTTCTCTCTCAATGGTGAACGTTGCACGGCGGGTTCGCGCATTTTTATTCAAGAGAGTCTCTATTCGGCAT
TTATTCAACGTTTTGCTGAGCGGGCCAGCCGTTTACGTGTGGGGGACCCACAAGATCTCGACACTCAAGTTGGCGCATTG
ATCAGTAAACCGCATTGGGACAAAGTTTCCGGCTATATCCAGTTGGGGATAGAGGAGGGGGCCACGTTGTTGGCAGGGGG
GCCGGATAAACCCATCGACCTACCTGCTCATCTGCGCGGAGGGCACTTCCTGCGTCCAACGGTGTTGGCCGATGTTGATA
ACCGAATGCGGGTTGCTCAGGAAGAGATTTTTGGACCGGTCGCTTGCCTGATCCCCTTTAAGAATGAAGACGCCGGACTG
CGTTTGGCAAACAGCGTGCCATACGGTCTGGCTGCTTATATCTGGACACAAGACGTCAGCAAAGTGCTGCGTTTGGCCCG
AAGTATTGAAGCCGGCATGGTGTTCGTGAATACCCAGAATGTGCGGGATCTCCGCCAGCCATTTGGCGGCATCAAGGCAT
CGGGAACCGGGCGTGAAGGGGGAAAGTACAGTTTTGATGTTTTTGCTGAAGTGAAAAACGTCTGTATTTCCATGGGGGAG
CATCCGATCCCCCGTTGGGGGATGTAA

Protein sequence :
MKIVNHWIDGKNITSKDYFTTINPATGEVLADVASGGIKEINQAVAAAKSAFPHWANLPMKVRARLMRRLGELIEQQIPE
IAQMETQDTGLPIYQTQNALIPRAAHNFEFFAEICQQMNGQTYPVDDQMLNYTLVQPVGVCALVSPWNVPFMTATWKVAP
CLALGNTAILKMSELSPLTADKLGELALEAGIPAGVLNVVQGYGATVGDALVCHQDVRAISFTGGTATGNRIMQRAGLKK
YSMELGGKSPVLIFDDADIERAMDAALFSIFSLNGERCTAGSRIFIQESLYSAFIQRFAERASRLRVGDPQDLDTQVGAL
ISKPHWDKVSGYIQLGIEEGATLLAGGPDKPIDLPAHLRGGHFLRPTVLADVDNRMRVAQEEIFGPVACLIPFKNEDAGL
RLANSVPYGLAAYIWTQDVSKVLRLARSIEAGMVFVNTQNVRDLRQPFGGIKASGTGREGGKYSFDVFAEVKNVCISMGE
HPIPRWGM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 0.0 85
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-74 42