Gene Information

Name : serS (RT0770)
Accession : YP_067708.1
Strain : Rickettsia typhi Wilmington
Genome accession: NC_006142
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 980639 - 981916 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAAATATCAAATGGATTAGAGAAAATCAAGAATTATTCGATGAAAAATTGAGCCAAAGATTTATTGAACCTATGTC
TAGTAAAATTGCTATGCTAGACCGAGAAAAAAGAAAAATTACGAGTTTAATTCAGGAATTTCAGCATGCACGTAAGGTAA
AATCAAAGATTTTAGGTAATATGGTCTCTAAAAGTGGCGAAGAGTTTGAAGAATTACAAAGAGATGTTAACCATATAAAT
GAGAAGTTAGAAGAACTTGAACAAACTCTAGATAATAATAACGAATTAAATGAACTATTAAATATGCTTCCTAATATTCC
GGACGAGGAAGTACCTTACGGGATCGATGAAAGTATGAATAAATTAGTGCGTTCTTACGGCAACACAAATAAAAATGCTT
TGAATAAACAGCATTTTGAATTAGGTACAAAATTAAATTTAATGGATTTTGAACAAACAGCTAAAATTTCTGGATCTAGA
TTTGTAACGTTAAAAGGTGATTTAGCAAAGTTAGAACGTGCTTTAATTAATTTTATGGTTGACATTCATACTAAAGAGTT
TGACTTCTTTGAGATATCACCTCCATTATTAGTTCGAGATAGTGCTATGTATAATGCAGGACAACTACCTAAGTTTTCTG
AAGAATCTTTTATAACAACAAATGGTTATAGACTAATTCCAACCGCAGAAGTATCTTTAGTAAATATAGTAGCCGATACT
ATTATACAAAGAGAAAAATTACCTATGCGTTACGTTGCTTACACCACGTGTTTTAGATCAGAAGCAGGTAGTAGTGGTAG
AGATACAAGAGGCATGATTAGATTACATCAGTTTGGTAAAGTTGAACTCGTATCTATTACTACCCCTGAAGAATCAAAAA
ATGAGCATGAATATATCACTAATGCATCAGAGACGATTTTAAAAAAACTCGATCTCCCGTATCGTGTTATGCTACTTTGT
ACTGGCGATATGGGATTTGCAGCGAAAAAAACTTATGATATAGAAGTATGGCTTCCTGGACAAAATCAATATCGTGAAAT
TGCAAGCTGTTCTAATTGTGGTGATTTTCAAGCACGTAGAATGAAAGCAAGATATAAGGAATTCGGTAGTAATGAAACTA
CATTAGTACATACTTTAAATGCTTCAGGATTACCTATTGGTAGAACTATAGTTGCAATACTTGAGAATTATCAGAATAAC
GATGGATCAATAACTATACCTGATGTCTTAATAAATTACATGGGAGGATTAAAAAAAATCACTACATATAGTGAATAA

Protein sequence :
MLNIKWIRENQELFDEKLSQRFIEPMSSKIAMLDREKRKITSLIQEFQHARKVKSKILGNMVSKSGEEFEELQRDVNHIN
EKLEELEQTLDNNNELNELLNMLPNIPDEEVPYGIDESMNKLVRSYGNTNKNALNKQHFELGTKLNLMDFEQTAKISGSR
FVTLKGDLAKLERALINFMVDIHTKEFDFFEISPPLLVRDSAMYNAGQLPKFSEESFITTNGYRLIPTAEVSLVNIVADT
IIQREKLPMRYVAYTTCFRSEAGSSGRDTRGMIRLHQFGKVELVSITTPEESKNEHEYITNASETILKKLDLPYRVMLLC
TGDMGFAAKKTYDIEVWLPGQNQYREIASCSNCGDFQARRMKARYKEFGSNETTLVHTLNASGLPIGRTIVAILENYQNN
DGSITIPDVLINYMGGLKKITTYSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-78 45