Gene Information

Name : hemC (RT0453)
Accession : YP_067411.1
Strain : Rickettsia typhi Wilmington
Genome accession: NC_006142
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 582670 - 583569 bp
Length : 900 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGATAAATTCTATCAGAATAGGCACAAGAAATAGTACACTTGCTTTAATACAGACTAATTTAGTTATTGCGCAAATAAA
ACAATTTTTTCCTGATATTAATTGTGAAATAGTACCTATTATTACTAGCGGTGACTTAATTCAAAATAAACCATTATACG
ATATAGGTGGTAAAGCTTTATTCTTAAAGGAAATAGAGCAAGCATTGCTTGATAAAAAAATTGACTTAGCTGTTCATTCT
TTGAAAGATATACCTGGTAGAATACCTGTAGATCTAGTAATAGCTGCAGTTTTAGAGCGCGAAGATCCAAGAGATGTTTT
GGTATGTTTAAATTATAAATCTATAGAAACACTTCCGCAAAATGCGGTAATAGGTAGCTCAGCAGTACGAAGAAAAGCAT
TTATAAAAAAAATAAGACCTGATTTAAATATAAAAGTTTTTAGAGGCAATGTTGATTCAAGAATAAAAAAGCTAATGACA
GGTGAAGTTGATGCAACAATTCTATCATATGCAGGTCTAAAAAGGCTTAATGCATTTAATAAGAAATATTGTCATCTTAT
AGAGTATTCGCAGATATTGCCATGTGTAGGGCAGGGAGTCATTGCAGTCGAGATCAGAAAAGACGATAATGCTATGTTTA
ATATATGTAATCAAATTAATCATATTCCAACCTTTGAATTAATAAAACCTGAAAGAGCATTTTTAGAACATCTAGATGCT
AATTGCAGTACACCGATTGGTGCGTACTCACAATACCTAGATGCGTATAATATACAAACAGATTTTATGCTTGGTAAGCT
TGATTGTAATAAAATAATATTCCAAACTGAAATTACCAATATTAATACCTCAAGAGAATGTGGCATCAAAGCTGCTAAAA
TGATGTTGGCACAACAATAA

Protein sequence :
MINSIRIGTRNSTLALIQTNLVIAQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKALFLKEIEQALLDKKIDLAVHS
LKDIPGRIPVDLVIAAVLEREDPRDVLVCLNYKSIETLPQNAVIGSSAVRRKAFIKKIRPDLNIKVFRGNVDSRIKKLMT
GEVDATILSYAGLKRLNAFNKKYCHLIEYSQILPCVGQGVIAVEIRKDDNAMFNICNQINHIPTFELIKPERAFLEHLDA
NCSTPIGAYSQYLDAYNIQTDFMLGKLDCNKIIFQTEITNINTSRECGIKAAKMMLAQQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-45 41
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-45 41