Gene Information

Name : guaA (DP0903)
Accession : YP_064639.1
Strain : Desulfotalea psychrophila LSv54
Genome accession: NC_006138
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1017119 - 1018669 bp
Length : 1551 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGATATTCATAAGGAAAAAATCATTATTCTCGACTTTGGTTCACAGACCACTCAGCTGATTGCTAGACGGGTGCGTGA
AATGAAGGTTTACAGTGAAATTCACCCATTTTCTCTACCTCTGGAGAAGTTAAAGGAGCTGAACCCGACCGGAATAATTC
TTTCTGGTGGCCCATGTTCTGTTTACGATGATGATGCACCGCATTCCGATGCGGGTCTTTTTGAGTTGGGTGTGCCCGTA
TTCGGTATCTGTTACGGCGCTCAGTTGATGATTCAGCAGCTTGGCGGCAGTGTAGAAAAGGCAGAAAAACGAGAGTTTGG
TAAGGCCGAGATCCAGATTCTCAACGATAGTGACCTCTTTGCCGGTCTTGATGTAGCCAGGAGTCACCAAGTATGGATGA
GTCACGGTGATCGTGTTGAGGTTATCCCTGACCAGTTTGAGGTAAGTGCAGAATCTGCCCACTCTCCCTATGCAGCTCTG
CGTCACAGGTCAAAACCATTTGTTGCCGTACAGTTTCACCCGGAGGTTGTGCACAGCATTATCGGTACTGATCTGTTGAG
AAACTTTGTCTTTGGCCTTTGTAAATGTCAGGCAACCTGGACCATGCAGGGTTTTATCGAGTCCAATGTTGCGGCTATTA
AAGAGAAGGTGGGCGATGCCCATGTTATCTGTGCCCTTTCAGGTGGTGTTGATTCCTCCGTTGTGGCGGCGATGATTCAC
AAGGCCATTGGCTCTCAGTTGACCTGTGTTTATGTAAACAACGGTCTCATGCGTATTGGTGAGTCCGAGGGTATTATCAA
GTTCTTTAAAGAGAATACCGATCTTCACCTCATTGATGTTGATGCCAGCGATTATTTCCTGGGTAAACTTGAAGGTGTTA
CTGATCCTGAGGTTAAGCGTCAGCATATCGGTCTTGGCTTTATCAAGATCTTTGAGGAAGAGGCACATAAGATTGATGGC
GATGTGAAGTTTCTTGCTCAAGGAACTCTCTATCCCGACGTGGTAGAGTCTGTCTCTTTTCGTGGTGCAGCACCTATTAA
GTCTCACCATAATGTAGGCTGCCTGCCCGATATCATGAAGCTTAGTCTTATTGAGCCCCTTCGTGAGCTCTTCAAGGATG
AGGTGCGTGAGCTTGGTGTAGAGCTTGGTCTGCCCGATGAGGCGGTTCATCGTCAGCCTTTCCCTGGTCCTGGTCTTAGT
ATTCGTATCATGGGCGAGGTAACTCCCGAGCGTTTGGATATCGTCCGTCGTGCTGATGTTATCGTCCTGGATGAGATGAA
AAAGCATGGCTACTATAACAAGGTATGGCAGTCATTTGCCGTGCTTCTGCCTATCCAGACAGTCGGCGTAATGGGTGACT
TTCGTACCTATGAGCATGTTGTTGCCCTGCGGGTAGTTGATTCTCGTGATGCTATGACCGCGGATTGGAGCCGGGTACCC
TATGATATTCTTGGTGATATTTCCACCAGGATTATTAATGAGGTGCGGGGAGTTAATCGGGTTGTCTACGATATCTCTTC
CAAACCACCTGCAACGATAGAGTGGGAGTAG

Protein sequence :
MDIHKEKIIILDFGSQTTQLIARRVREMKVYSEIHPFSLPLEKLKELNPTGIILSGGPCSVYDDDAPHSDAGLFELGVPV
FGICYGAQLMIQQLGGSVEKAEKREFGKAEIQILNDSDLFAGLDVARSHQVWMSHGDRVEVIPDQFEVSAESAHSPYAAL
RHRSKPFVAVQFHPEVVHSIIGTDLLRNFVFGLCKCQATWTMQGFIESNVAAIKEKVGDAHVICALSGGVDSSVVAAMIH
KAIGSQLTCVYVNNGLMRIGESEGIIKFFKENTDLHLIDVDASDYFLGKLEGVTDPEVKRQHIGLGFIKIFEEEAHKIDG
DVKFLAQGTLYPDVVESVSFRGAAPIKSHHNVGCLPDIMKLSLIEPLRELFKDEVRELGVELGLPDEAVHRQPFPGPGLS
IRIMGEVTPERLDIVRRADVIVLDEMKKHGYYNKVWQSFAVLLPIQTVGVMGDFRTYEHVVALRVVDSRDAMTADWSRVP
YDILGDISTRIINEVRGVNRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-141 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-141 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-141 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-127 52