Gene Information

Name : DP2214 (DP2214)
Accession : YP_065950.1
Strain : Desulfotalea psychrophila LSv54
Genome accession: NC_006138
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2548939 - 2549517 bp
Length : 579 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
GTGTCCTCCTTTGGCGCAGAGTATGTAATGACTCGTTCAGATCATGTTTCCGGCTCAGATCGGCTGGCAGAGGCCGCTGA
GAAGATCGGTATTTCTGAACATGATGTGGTGGTGAATATTCAGGGTGATCAACCTCTTTTTGACCAGGCCGTTATAGAGC
AGGTGACAGCCCCTCTTATAGAGGATCCCTCTCTTCCCATGTCGACACTTATCTATAAGATTATTCGTCCAGAAGAGATC
AATGATCCCAATCATGTAAAGACAGTTTTTGATAAAAATGGCAATGCCCTCTATTTCTCTCGTTCGCCCATTCCCTTTCA
GAGAAATCCCGAGGAGGATGGTATTCCAACCTATTATAAGCATCTTGGCTTTTATGCCTATCGTAAAGGTTTTTTATTGT
CCTATGTGGCTTTACCGGAGGGAGAGTGGGAAAAATTTGAAAAACTGGAACAACTTCGAGCCCTTGAATATGGATACAGG
ATTCGAGTGACGGTGACAGAGCACGACTCTATTGAAGTTGACACCCCAGAAGATCTAAAACGGGTTGAGGCGCATTTGCT
GGAGCTGGAGCAGGCATAG

Protein sequence :
MSSFGAEYVMTRSDHVSGSDRLAEAAEKIGISEHDVVVNIQGDQPLFDQAVIEQVTAPLIEDPSLPMSTLIYKIIRPEEI
NDPNHVKTVFDKNGNALYFSRSPIPFQRNPEEDGIPTYYKHLGFYAYRKGFLLSYVALPEGEWEKFEKLEQLRALEYGYR
IRVTVTEHDSIEVDTPEDLKRVEAHLLELEQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 8e-30 42
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 4e-30 42
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-29 42