Gene Information

Name : metB (Lxx03230)
Accession : YP_061447.1
Strain : Leifsonia xyli CTCB07
Genome accession: NC_006087
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 320962 - 322116 bp
Length : 1155 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGACACACGGTTTCTCCACCCGCGCCATCCACATCGGCCAGGAGCCCGACCCGACGACGGGCGCGATCATCCCGCCGAT
CCACCAGACCTCGACCTTCGTCCAGGACGGCATCGGCGGTCTGCGCAGCGGCTACGAGTACGGCCGCGCTGCCAACCCCA
CCCGGGATTCGCTGCAGTCGCTGCTCGCCTCGCTGGAAGGCGGCGTCTCCGCGCTGTCCTTCGCTTCCGGCCTCGCCGCC
GAAGACGCTCTGCTGCGCGCCGTGCTCAGACCCGGCGACCATATCGTCCTCGGCAACGATGTCTATGGTGGCACGCACCG
TCTGATCGACCGCATCCACGGCGCCTGGGACGTCCGCAACACCACGGTCGACCTGACCGACCTGGACGCGGTGGGCGTCG
CCCTCGCGACCGGCCGCACCCGTCTGCTCTGGATCGAGACCCCGAGCAACCCGCTGATGAAGATCAGCGACCTGGCCGCC
TTGACCTCCCTCGGCCACGGCGCCGGTGCGCTCGTCGTCGTGGACAACACCTTCGCCTCGCCCGCGCTTCAGCAGCCGCT
GTCGTTCGGCGCGGATGTCGTCGTCCACTCGACCACCAAATACCTCGGCGGTCACTCCGACGTGATCGGCGGCGCGCTCG
TCTTCGGCGGCGAGGAGCTCGCCGAGAAGGTGCGGTTCATCCAGTTCGCCGCCGGGGCCGTCTCCGTGCCGATGGATGCC
TGGCTCACCGTCCGTGGCATCAAGACCCTCGCCGTCCGCATGCAGCGCCACACCGAGAACGCGCAGGCGATCGCAGACGC
CCTCCTCGGACGCCCCGGCGTCCAGGCGGTCTATTACCCCGGACTGCCGACGCATCCGGGCCGCGCCCTCGCCGTCCGCC
AGATGAGCGGCTTCGGCGGGATGCTCTCTGTCGCCCTCGCCGGCGGAGCCGCGGTGGCGCGCCGGTTCGCCGAGTCCACC
GAAGTCTTCCAGCTCGCGGAGTCGCTCGGCGGCGTCGAGTCCCTCATCGGCTATCCGGCCGAGATGACCCACGCCTCCGT
GCGCGGCACGGAACTCGACGTGCCCGGTAACGTGATCCGCCTGTCGGTCGGAATCGAGGACATCGCCGACCTGCTGGCGG
ATGTCGAGCAGGCGCTGGGGCGGGCGTCGCTCTAG

Protein sequence :
MTHGFSTRAIHIGQEPDPTTGAIIPPIHQTSTFVQDGIGGLRSGYEYGRAANPTRDSLQSLLASLEGGVSALSFASGLAA
EDALLRAVLRPGDHIVLGNDVYGGTHRLIDRIHGAWDVRNTTVDLTDLDAVGVALATGRTRLLWIETPSNPLMKISDLAA
LTSLGHGAGALVVVDNTFASPALQQPLSFGADVVVHSTTKYLGGHSDVIGGALVFGGEELAEKVRFIQFAAGAVSVPMDA
WLTVRGIKTLAVRMQRHTENAQAIADALLGRPGVQAVYYPGLPTHPGRALAVRQMSGFGGMLSVALAGGAAVARRFAEST
EVFQLAESLGGVESLIGYPAEMTHASVRGTELDVPGNVIRLSVGIEDIADLLADVEQALGRASL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-66 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-66 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_061447.1 cystathionine gamma-synthase BAC0207 Protein 2e-63 45