Gene Information

Name : guaA (Lxx19780)
Accession : YP_062798.1
Strain : Leifsonia xyli CTCB07
Genome accession: NC_006087
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2040368 - 2041879 bp
Length : 1512 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGCGCGAGGCGAACGTCTACTCCGAGATCGTGCCGCACACCGTCACTGCTGCCGACATCGCGGCCAAACGCCCTGCGGG
CATCATCCTCTCCGGCGGGCCGTCCAGCGTCTACGAGGAGGGCGCGCCTCGTCTGGACGAGGGCATTTTCGAGCTCGGCG
TTCCGGTGCTCGGCATCTGCTATGGCTTTCAGGTCATGGCGGTCGCGCTCGGCGGCGAGGTCGCGAAGACCGGCCACCGA
GAGTACGGTTCCACGGCGGTGCGTGTCTCCGCGGGCGCCCGGGGCGGAGCGGGCTTTTTGCTGGACGGCCAGCCCGGCGA
TCAGACTGTGTGGATGTCGCACGGCGACTCGGTCGCCAAAGCGCCCGAGGGCTTCGACGTCCTCGCCTCCACGGACGACA
CCCCGATCGCCGCGTTCGCGAACGACGGGCGGAAGCTCTACGGCGTCCAGTGGCATCCCGAGGTCAAGCACTCGGAGCAC
GGCCAGGCGGTGCTCGAGAACTTCCTGCACCGTGCTGCGGGCATCCCGGCCGACTGGAACTCCGGCAATGTCATCGCCGA
TCAGGTCGCCGCGATCCGCGCCCAGGTCGGCTCCGGCCGCGTGCTGTGCGCCCTGTCCGGCGGAGTGGACTCCGCGGTCG
CCGCCGCGCTCGTCCACAAAGCCATCGGCGACCAGCTCGTGTGCGTTTTCGTGGATCACGGCCTCCTCCGCCGGGACGAG
GCGCGGCAGGTCCAGGAGGACTACGTTTCGGCGACCGGGGTCCGGCTCATCACGGTGGACGCGGAGGAGCAGTTCCTCGC
CGCACTGGAGAGCGTGAGCGACCCCGAGGCCAAGCGCAAGATCATCGGCCGCGAGTTTATCCGCGTTTTCGAGCGGGCTC
AGGCCGACCTCGTCGCCGAAGCCGCGAGCGAAGGCGACCCGATCCGCTTCCTCGTGCAGGGCACGCTCTATCCGGATGTC
GTGGAGTCGGGCGGCGGCGCGGGAACCGCGAACATCAAGAGCCACCACAACGTGAGCGGCCTGCCGGAGGACTTGCAGTT
CGAGCTCGTGGAGCCGCTGTGTACGCTCTTCAAAGACGAGGTCCGCGCCATCGGCCGCGAGCTCGGCCTGCCCGAGGTCA
TTGTCGGCCGCCAGCCCTTCCCCGGGCCGGGGCTGGGCATTCGCATCGTGGGCGATGTGACACGCGAGCGTCTCGACCTG
CTGCGCGACGCAGACGCCATCGTTCGCGCCGAGCTGACCGCTGCCGGTCTCGACAGTGAGATCTGGCAGTGCCCCGTCGT
GCTGCTGGCGGACGTGCGCTCGGTGGGCGTGCAGGGCGACGGCCGCACTTACGGCCACCCGATCGTGCTGCGCCCCGTTT
CCAGCGAGGACGCGATGACCGCTGACTGGACCCGCCTGCCCTACCATCTGCTCGCGAAGATCTCCAACCGCATCACCAAC
GAGGTGGAAGGGGTCAACCGCGTGGTCCTCGACGTCACATCGAAGCCGCCGGGAACGATCGAGTGGGAGTGA

Protein sequence :
MREANVYSEIVPHTVTAADIAAKRPAGIILSGGPSSVYEEGAPRLDEGIFELGVPVLGICYGFQVMAVALGGEVAKTGHR
EYGSTAVRVSAGARGGAGFLLDGQPGDQTVWMSHGDSVAKAPEGFDVLASTDDTPIAAFANDGRKLYGVQWHPEVKHSEH
GQAVLENFLHRAAGIPADWNSGNVIADQVAAIRAQVGSGRVLCALSGGVDSAVAAALVHKAIGDQLVCVFVDHGLLRRDE
ARQVQEDYVSATGVRLITVDAEEQFLAALESVSDPEAKRKIIGREFIRVFERAQADLVAEAASEGDPIRFLVQGTLYPDV
VESGGGAGTANIKSHHNVSGLPEDLQFELVEPLCTLFKDEVRAIGRELGLPEVIVGRQPFPGPGLGIRIVGDVTRERLDL
LRDADAIVRAELTAAGLDSEIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWTRLPYHLLAKISNRITN
EVEGVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-165 68
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-129 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-128 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-129 52