Gene Information

Name : nrdF (M6_Spy0372)
Accession : YP_059690.1
Strain : Streptococcus pyogenes MGAS10394
Genome accession: NC_006086
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 383317 - 384330 bp
Length : 1014 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGACCCAACATTATTATGAACGTTCGCAATCCCCAATTGAATACGCCCTATCTGAAACACAAAAACAGTTGCGCTCCAT
CAATTGGAATTACCTTAATGATGACAAAGATTTGGAAGTGTGGAACCGTGTCACTCAAAATTTTTGGTTGCCTGAAAAGG
TTCCTGTTTCTAATGATTTAAATTCTTGGCGCTCCTTGGGTGAGGATTGGCAACAGCTCATCACAAGGACCTACACTGGG
TTGACCTTACTAGATACAGTACAAGCAACGGTTGGTGATGTGGCACAAATTCAGCATTCACAAACTGACCACGAACAAGT
CATCTATACGAACTTTGCCTTTATGGTGGGGATCCATGCCCGCTCTTACGGGACGATTTTTTCGACCCTTTGCAGTAGCG
AGCAAATCGAAGAAGCACATGAATGGGTGGTCTCAACACAGAGCTTGCAAGACCGTGCCCGTGTCTTGATTCCTTACTAT
ACGGGTGATGACCCTTTGAAATCAAAAGTAGCAGCAGCTATGATGCCAGGATTTTTGCTGTATGGCGGCTTTTACCTTCC
TTTTTACCTATCAGCACGTGGTAAAATGCCAAACACATCTGATATCATCCGCCTGATTTTACGCGACAAAGTTATTCACA
ACTATTACAGCGGTTACAAATACCAACAAAAAGTAGCACGTCTTAGCCCAGAAAAACAGGCTGAAATGAAGGCCTTTGTC
TTTGACCTGCTCTATGAACTCATCGACCTTGAAAAAGCTTACTTGAGAGAACTGTATGCAGGCTTTGATTTGGCAGAAGA
TGCTATCCGTTTTAGCCTTTATAACGCTGGAAAATTCCTTCAAAATTTAGGTTATGACTCGCCCTTCACAGATGAAGAAA
CGCGCGTTTCACCAGAAGTATTTGCTCAGCTATCAGCGCGTGCAGACGAAAACCATGACTTTTTCTCAGGCAATGGCTCA
TCTTATGTGATGGGGATCACCGAAGAAACAACAGATGACGATTGGGAGTTTTAA

Protein sequence :
MTQHYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRVTQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTG
LTLLDTVQATVGDVAQIQHSQTDHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYY
TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSGYKYQQKVARLSPEKQAEMKAFV
FDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNAGKFLQNLGYDSPFTDEETRVSPEVFAQLSARADENHDFFSGNGS
SYVMGITEETTDDDWEF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 1e-71 53