Gene Information

Name : M6_Spy1506 (M6_Spy1506)
Accession : YP_060824.2
Strain : Streptococcus pyogenes MGAS10394
Genome accession: NC_006086
Putative virulence/resistance : Unknown
Product : aminotransferase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : 2.6.1.2
Position : 1497162 - 1498376 bp
Length : 1215 bp
Strand : -
Note : broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor

DNA sequence :
ATGAAAATTATTGAAAAATCATCAAAATTAGAACATGTTGCCTATGATATTCGAGGGCCTGTTTTGGATGAAGCTAATCG
CATGATTGCGAGTGGTGAAAAAATTCTGCGTTTAAATACTGGCAATCCTGCTGCCTTTGGTTTTGAAGCACCAGATGAAG
TGATTCGTGATTTAATTGTCAACGCGAGGCTAAGTGAGGGCTATTCTGACAGTAAAGGGATTTTTTCAGCACGTAAGGCT
ATCATGCAGTATTGCCAACTCAAGGGCTTCCCAGATGTTGACATTGAAGATATTTATTTGGGAAATGGCGTGTCAGAGTT
GATATCCATGTCCCTTCAAGCTTTGCTAGATAATGGCGATGAAGTTTTAGTACCAATGCCGGATTATCCTTTATGGACGG
CTTGTGTGAGTCTTGGTGGAGGAAAAGCAGTCCATTATCTTTGTGATGAAGAAGCTGGTTGGTATCCTGATATTGCTGAT
ATCAAATCAAAAATCACGAGTCGCACCAAAGCTATTGTGGTCATCAATCCTAATAACCCAACAGGAGCCCTTTATCCTAA
GGAGATTTTAGAAGACATCGTTGCTTTGGCAAGAGAACACCAGCTGATTATTTTTGCCGATGAAATCTATGATCGTTTGG
TGATGGATGGTAAAGAGCATATTGCTATTGCAAGTTTGGCACCTGATGTTTTTTGTGTATCTATGAATGGCCTTTCCAAA
TCTCATCGTATTGCTGGTTTTCGTGTTGGATGGATGGTCTTATCAGGTCCTAAAGACCATGTTAAAGGTTACATTGAAGG
GTTGAACATGCTTGCCAATATGCGGTTATGCTCCAATGTTTTAGCTCAACAAGTTGTTCAAACTTCCTTAGGAGGCCATC
AATCAGTTGATGCACTGTTACTGCCAGGAGGGCGTATTTTTGAGCAACGTAATTTTATTTATGAAGCTATTAATGCTATC
CCTGGCTTATCGGCAGTTAAACCTGAAGCAGGTCTTTATTTATTTCCGAAAATTGATCGTCAGATGTATCGTATTGATGA
TGATGAAGAATTTGTCTTACAGTTATTAAAGCAAGAAAAAGTGATGTTGGTACATGGACGTGGTTTTAACTGGAAAGATC
CAGATCACTTCCGTATTGTTTACCTACCAAGTGTAGAAGAATTAGAAGATGTTCAAGAAAAGATTACACGTGTCTTATAC
CAGTATAGACGTTAA

Protein sequence :
MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPAAFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKA
IMQYCQLKGFPDVDIEDIYLGNGVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGKEHIAIASLAPDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRLCSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAI
PGLSAVKPEAGLYLFPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQEKITRVLY
QYRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-117 57
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 2e-117 57
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-117 57
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-117 57