Gene Information

Name : nadE (M6_Spy1403)
Accession : YP_060721.1
Strain : Streptococcus pyogenes MGAS10394
Genome accession: NC_006086
Putative virulence/resistance : Unknown
Product : NAD synthetase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0171
EC number : 6.3.1.5
Position : 1398438 - 1399304 bp
Length : 867 bp
Strand : -
Note : catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli

DNA sequence :
TTGATAACATTCGCAAAGATGCTTATGGAAAGAGTGAATGACATGACATTACAAGAAGAGATCATTCGACAATTAGGCGT
CAAGGCTAGCATTGATCCGAAAGAAGAAATTCGGAAAACCGTTGATTTTTTAAAAGCTTATCTGCGTAAGCACTCATTTT
TGAAAACTTATGTCTTAGGCATTTCTGGAGGTCAGGATTCTACCCTCGCAGGAAAGCTAGCCCAGATGGCCATTGCAGAG
TTACGGGAGGAAACAGGTGATCAAGCTTACCAATTTATAGCTGTTCGCTTGCCTTATGGGGTTCAGGCTGATGAAGCAGA
TGCGCAAAAGGCCTTGGCTTTTATTGCACCAGATCAGACCCTTACCATTAATATCAAGGCAGCTGTGGACGGTCAAGTAG
AGGCTCTACAAGCAGCAGGCGTTGAGATTTCTGATTTCAATAAAGGTAATATTAAAGCACGTCAGCGAATGATCAGTCAA
TATGCCATTGCTGGCCAAATGGCTGGTGCTGTTATTGGAACGGATCATGCGGCAGAAAACATCACTGGTTTCTTTACTAA
ATTTGGTGATGGTGGAGCAGATATTCTTCCCCTCTTTAGGCTTAACAAACGTCAAGGAAAGGCTCTTTTGAAAGTTTTAG
GAGCAGATGCTGCTTTGTATGAAAAAGTTCCAACTGCTGATTTAGAAGATCAAAAACCAGGCTTGGCTGATGAGGTTGCT
CTAGGGGTGACCTATCAAGACATCGACGACTATTTGGAAGGGAAGCTGATTTCCAAAGTAGCTCAAGCAACTATTGAAAA
ATGGTGGCATAAAGGACAACACAAGCGTCACCTGCCAATCACCATTTTTGATGATTTTTGGAAATAA

Protein sequence :
MITFAKMLMERVNDMTLQEEIIRQLGVKASIDPKEEIRKTVDFLKAYLRKHSFLKTYVLGISGGQDSTLAGKLAQMAIAE
LREETGDQAYQFIAVRLPYGVQADEADAQKALAFIAPDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQ
YAIAGQMAGAVIGTDHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQKPGLADEVA
LGVTYQDIDDYLEGKLISKVAQATIEKWWHKGQHKRHLPITIFDDFWK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadE YP_001800880.1 NAD synthetase Not tested Not named Protein 9e-62 54