Gene Information

Name : M6_Spy1155 (M6_Spy1155)
Accession : YP_060473.1
Strain : Streptococcus pyogenes MGAS10394
Genome accession: NC_006086
Putative virulence/resistance : Unknown
Product : phage-related DNA polymerase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 1154346 - 1156301 bp
Length : 1956 bp
Strand : +
Note : -

DNA sequence :
ATGCCGATTAAAGAACTTAGCATCGACATTGAAACCTATTGCGAAATTGACCTACGAAAATCTGGTGTCTATCGCTATGC
GGAAGATGACAGTTTTGAACTCCTTTTAATTGCAGTTTCTGTCGATAATGGACCAGTGACTGTTTACGACTTTAATAAAG
AGAAGTTACCACAAGATATTCTTGAAGCTTTAGTAGAAGATAGAGTCATCAAATGGGCATTCAACGCTTCATTTGAGCGA
ATTTGCCTATCCAACTGGCTCAAGAAACATCATCCTGAATTCTTATCAGATGGATTTCTCTCCCCAGTTTCGTGGCGATG
TAGCATGATTTGGTCCGCCTATTTAGGACTTCCACTCTCCCTTGAAGGAGTTGGAACAGTTCTCAAACTCAAAGACCAAA
AGATGAGAGAGGGGGCTGACCTTATTCGCTACTTCTGCTTGCCTTGTAAGCCAACCAAAGTCAATGGGGGACGAATTCGT
AACTTTCCTCATCACGCACCTAACAAGTGGTCTACATTTATCGACTACAACAGACGTGATGTTGAGGTCGAATTGGCCAT
CAAGGAACGGGTGAAAAACTTCCCAGTACCTAGCTTTGTTTGGAATGAGTACCACCAGGATCAGATTATCAACGACCGCG
GTATTGGCATAGATGTTGACTTTGTAAAAGCTGCTTTAAAAATAGACGGAGAGAGCAAAGCCAAAATTCAAGCAGAGTTA
AAAACATTAACGGGTCTTGAAAAACCCAACTCTGTTCTGCAGATGATTAGTTGGTTGCGAGAACACGGAGTAGCAACAGA
TTCTCTAGACAAAAAAGCTGTGAAAGAATTACTCAAAACGGTTGATGAAACAACTGCTCAAGTTCTCAAACTTCGTCAGC
AAGCTGCCAAATCAAGTGTCTCCAAATACCAGGCTATGATGAACTGTGTTTGTAAAGACGGTCGAGCAAGAGGAATGTTT
CAATTTTTCGGGGCTAATCGTACAGGTCGTTGGGCTGGTCGCTTGGTACAACTTCAGAATTTACCACAGAACCATCTTCC
TGACCTAAAGGAAGCTAGAGAACTTTTCAGAACAGGTGACTTAGAATCTACTGAGCTACTCTACGACACACAAGATACCT
TATCTCAACTTATCCGAACAGCCTTTGTCCCTAGTAAAGGAAAGAAATTCATTGTTTGCGACTTTTCAGCTATCGAAGCT
CGTGTACTCTCCCACCTGGCAGGAGAGAGATGGCGCAGTAAAGTATTTGAACAAGGGAAAGACATCTACTGTATGTCCGC
TTCTCAGATGTTTGGAGTACCAGTTGAAAAACATGGACAAAATTCTGAACTCAGGCAAAAAGGAAAAATTGCAGAGCTTG
CTTGCGGCTATGGTGGTTCAGTCGGTGCATTGAAAGCCATGGGAGCACTTGATATGGGACTATCAGAGGAAGAACTCCAA
CCACTTGTTAACTCATGGCGACAAGCAAATCCGAATATCGTTCTCTATTGGTGGGATGTCGATAATGCTGTAAAGACTGC
TGTAAAGGAACTACTTCCAACATCTACTCAAAATATTCAATTTGAAGTCAAAAGTGGTATATTGTTCATCACCCTTCCTT
CTGGTCGCAAACTAGCGTATATCAAACCAAGAATTGGCGAGAACCAGTTCGGTGGAGAGTCCGTCACTTACGAAGGAACT
GGAACTGCCAAACGTTGGGAGAGGTTAGAAAGCTACGGTCCAAAATTTGTAGAGAACATTGTTCAAGCTATCAGTAGAGA
CATACTTGCGTTCTCTATGAAGCAACTAAATGATTTCAAGATTGTAGGCCATGTCCACGATGAAGTAATAATCGAATGTC
CAATTGAACAAAAACTTGATGAAGTTGCATCATTAATGGGGATAGCACCTTACTGGTTGTCTGATATTAATCTTAGGGCT
GATGGATATGAATGCTTTTTCTATCAAAAAGACTAG

Protein sequence :
MPIKELSIDIETYCEIDLRKSGVYRYAEDDSFELLLIAVSVDNGPVTVYDFNKEKLPQDILEALVEDRVIKWAFNASFER
ICLSNWLKKHHPEFLSDGFLSPVSWRCSMIWSAYLGLPLSLEGVGTVLKLKDQKMREGADLIRYFCLPCKPTKVNGGRIR
NFPHHAPNKWSTFIDYNRRDVEVELAIKERVKNFPVPSFVWNEYHQDQIINDRGIGIDVDFVKAALKIDGESKAKIQAEL
KTLTGLEKPNSVLQMISWLREHGVATDSLDKKAVKELLKTVDETTAQVLKLRQQAAKSSVSKYQAMMNCVCKDGRARGMF
QFFGANRTGRWAGRLVQLQNLPQNHLPDLKEARELFRTGDLESTELLYDTQDTLSQLIRTAFVPSKGKKFIVCDFSAIEA
RVLSHLAGERWRSKVFEQGKDIYCMSASQMFGVPVEKHGQNSELRQKGKIAELACGYGGSVGALKAMGALDMGLSEEELQ
PLVNSWRQANPNIVLYWWDVDNAVKTAVKELLPTSTQNIQFEVKSGILFITLPSGRKLAYIKPRIGENQFGGESVTYEGT
GTAKRWERLESYGPKFVENIVQAISRDILAFSMKQLNDFKIVGHVHDEVIIECPIEQKLDEVASLMGIAPYWLSDINLRA
DGYECFFYQKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SEQ_2073 YP_002747288.1 phage DNA polymerase Not tested ¥ÕSeq4 Protein 3e-142 49
polA YP_494120.1 phage related DNA polymerase family A Not tested ¥ÕSa2 Protein 2e-138 47
MW1425 NP_646242.1 DNA polymerase Not tested ¥ÕSa2 Protein 2e-138 47