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Name : leuS (PPA0893) Accession : YP_055606.1 Strain : Propionibacterium acnes KPA171202 Genome accession: NC_006085 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 969866 - 972346 bp Length : 2481 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : GTGAGCGACCAGGTGCGCGAGACAACGGGCTACGACGCAGTCGCAGCCCAGGAGAAGTGGTCCAAGTATTGGGAGGAGCA CCGCACCTTCGCCTCCCTTGATGACGGCTCCAGGGAGCGTCGCTACGTGCTTGACATGTTCGCCTACCCCTCCGGCGACC TTCACATGGGGCATGCTGAGGCGTTCGCCATTGGCGATGTGCTGGCCCGTTACTGGCGTCTGCGTGGATTCGACGTGTTG CACCCGGTGGGCTGGGACTCCTTCGGTCTGCCGGCTGAGAACGCCGCGATCAAGCACGGGACCCATCCCGCGGAATGGAC CTACCGCAATATCGACACTCAGGCGGCCTCTTTTAAGCGGTACGCGGTTTCCTTCGACTGGTCGATGAGGCTGCATACCT CAGACGAGGAGTACTACCGCTGGACCCAGTGGCTGTTTAACCGTTTCTTCGAAAAGGGACTGGCCTACCGTAAGGACTCC TGGGCTAACTGGTGCCCCATCGACCAGACGGTGCTCGCCAATGAGCAGGTCAAGGATGGGTGTTGCGAGCGTTGTGGTGC TGTCGTCACCAAGCGTCAGCTCAACCAGTGGTATTTCCGCATCACTGACTACGCTCAGCGCCTGCTCGACGACATGGACC AGATCGAGGGGAAATGGCCTGAGCGTGTGCTGTCGATGCAGCGCAACTGGATCGGTCGTTCCGAAGGTGCCTACGTTGAT TTCACGATTGATGGTCACAAGGAGCCAGTGAGGGTTTTCACCACCCGTCCGGACACCCTGTACGGAGCTACCTTCATGGT GGTGGCTCCTGACTCGGCCCTGGCCCAGGAGATCGTCTCCGATGAGGCCCGGCCAGCCTTTGAAACCTACCTCGATGAGG TCAAGAAGAAGTCCGAAATTGAGCGGCAAGCCACCGATCACGAGAAGACTGGAGTGCCCCTCGGGGTCGAGGCGACTAAT CCTGTCAATGGTGCCAAGGTTCCGGTGTGGGCTGGTGACTATGTGCTGGCGGACTACGGGACGGGTGCCGTCATGGCTGT GCCCGCCCATGACCAGCGCGACCTCGACTTCGCTCGCACATATGGCATTGACGTCATCCCGGTCATCGACACTGGCGAGG CTGATCCTCGCGAGTCTGGGGTCGCTACGACGGGTGATGGCGTTTACCAAAACTCCGGATTCCTCAATGGCATTGCCACT AAGGCTGAGGCCATCGCGAAAATGTGCGAATTCCTTGATGAAAAGGGGATCGGTGAGCCGACAATCACCTATCGGCTGCG CGACTGGCTGCTAAGCCGTCAGCGTTTCTGGGGATGCCCCATCCCGATCATCCATTGTGAGTCCTGCGGCGACGTCCCGG TCCCTGATGAACAGCTGCCAGTCAAGCTGCCTGATCTCCGCGGCGCCGAGCTTGCCCCTAAGGGAACGTCACCGCTGGCT GGCGAAGAGGCCAGCGAATGGCGTTCGGTGGCCTGCCCGTCGTGTGGGGGAGCTGCCCAGCGTGACACCGACACCATGGA CACCTTCGTGGACTCGTCGTGGTATTTCATGCGCTATTGCTGTCCGCACTATGACAAGGGCCCGTTTGATGTGGAGGCAG TTCGTCGTTGGATGCCGGTAGCCCAGTACATCGGTGGCGTCGAGCATGCCACTATGCACTTGCTGTACTCCCGGTTCTTC ACCAAAGTGCTGTATGACCTCGGCATGGTCGACTTCACCGAACCGTTCCAGCGGCTCATGAACCAGGGTCAGGTCATCAA TGAAGGCCGGGCAATGTCGAAGTCGCTGGGCAATGGCGTGGACCTCGGCAAGCAGATCGACGAGTTCGGTGTCGACGCAG TACGTACCACCGTTATCTTCGCCGGTCCACCAGATGAAGACATTGATTGGGCCGACGTCTCACCGGCCTCGACTCTAAAG TTTTTGCAGCGTGCCTGGCGCGTGGCTGCTGAGGTCACGAGCGATCCTGACGCTGACCTGACACAAGGCGACTCCACCCT GCGTCGGGTTACCCATCGCAGCATCGCCGACATCACCGAGTTGCTGGAGGGCGGGCGTTACAACGTCGTTGTGGCGCGGA TCATGGAACTGGTCAATGCCACCCGTAAGGCCATTGATTCGGGGTGCGGCCCAGCTGATCCTGCAGTGCGCGAGGCCGTC ACCTTTACTGCCCAGGCGCTATCTTTAGTGGCCCCGTACTTGGCTGAGGAGATGTGGGAGATGCTCGGCTTGGAGCCCTC GGTTGCCAACTCTCATTGGCCCACTGCTGACGAGAAACTGCTGGTAGCCGACAAGGTGACCATGGTCGTCCAGGTGACGG GCAAGGTACGCGCTAAGCTCACAGTGAGCCCCGATATCACCGAGGCCGAGGCCCGCGAGGTGGCTTTAGCCGACGTTAAT GTGCAGCGGTTTACTGAAGGTAAGGAGATCGTCAAGATCATTGCCAAGCTGCCGAAGATGATATCGATCGTCGCGAAATA A Protein sequence : MSDQVRETTGYDAVAAQEKWSKYWEEHRTFASLDDGSRERRYVLDMFAYPSGDLHMGHAEAFAIGDVLARYWRLRGFDVL HPVGWDSFGLPAENAAIKHGTHPAEWTYRNIDTQAASFKRYAVSFDWSMRLHTSDEEYYRWTQWLFNRFFEKGLAYRKDS WANWCPIDQTVLANEQVKDGCCERCGAVVTKRQLNQWYFRITDYAQRLLDDMDQIEGKWPERVLSMQRNWIGRSEGAYVD FTIDGHKEPVRVFTTRPDTLYGATFMVVAPDSALAQEIVSDEARPAFETYLDEVKKKSEIERQATDHEKTGVPLGVEATN PVNGAKVPVWAGDYVLADYGTGAVMAVPAHDQRDLDFARTYGIDVIPVIDTGEADPRESGVATTGDGVYQNSGFLNGIAT KAEAIAKMCEFLDEKGIGEPTITYRLRDWLLSRQRFWGCPIPIIHCESCGDVPVPDEQLPVKLPDLRGAELAPKGTSPLA GEEASEWRSVACPSCGGAAQRDTDTMDTFVDSSWYFMRYCCPHYDKGPFDVEAVRRWMPVAQYIGGVEHATMHLLYSRFF TKVLYDLGMVDFTEPFQRLMNQGQVINEGRAMSKSLGNGVDLGKQIDEFGVDAVRTTVIFAGPPDEDIDWADVSPASTLK FLQRAWRVAAEVTSDPDADLTQGDSTLRRVTHRSIADITELLEGGRYNVVVARIMELVNATRKAIDSGCGPADPAVREAV TFTAQALSLVAPYLAEEMWEMLGLEPSVANSHWPTADEKLLVADKVTMVVQVTGKVRAKLTVSPDITEAEAREVALADVN VQRFTEGKEIVKIIAKLPKMISIVAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 5e-159 | 42 |
