Gene Information

Name : hemC (PPA0304)
Accession : YP_055019.1
Strain : Propionibacterium acnes KPA171202
Genome accession: NC_006085
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 354200 - 355300 bp
Length : 1101 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGCCGCTCTGGTGCCGCAGGCCCGCCGAACTGTCCGTCAACTTGTCTGATTGCAGGCTGGAATCGGCGTCGGTACTGAG
TGCCACAATAGGCAATATGTCTGCGATCCGTCTGGGAACCCGTGCCAGCACTCTGGCCACTACTCAATCAGAGATGGTTG
CGGGGCTGCTCAGGTCGGAGGGGCTGGACGTCAATCTGACGACGATCACTACTCACGGGGACACCTCGACGGCCTCGTTA
GCGGCCATGGGAGGAATCGGGGTGTTCGCCTCGGCGATCCGTGCGGCCCTCCTCGAGGGAGAAGCCGACATTGCCGTCCA
CTCCTTCAAAGATCTACCGACAGGACGTCCGTTAGGACTGGCGATCGGTGCCGTTCCAGCTCGAGCAGACCCGCGTGACG
CTTTGGTGGCCCGCGATGGGCTCACCCTTCACGACCTCCCGCAAGAAGCTAGCGTCGGGACGGGCTCGCCACGTCGGGCC
GCACAGTTGTTGGCGGTCAGACCGGACCTGACGATCGTCGATATCCGTGGAAATGTCGACACTCGGCTGGGTCGCGTCAA
AGGACTCGGCCGCTACGCCAAAAACGGTGGCAAGGAGGACCTCGACGCCGTCGTGCTCGCAGCCTCCGGACTAGCTCGAC
TAGGTCATAGCGGCGCCGTCACTGAGTTCCTCGACCCGTCGGTAGTACTGCCTGCCCCTGCTCAGGGAGCGCTAGCCGTC
GAATGCCGGACCGCTGATTCACGTCATGGCAAGCTCGCCAAAGCGCTGGCACGGATTGACGACCGCAGAACCAGGCTGGC
CGCCACCGCCGAACGTGCGGTGCTCTCCCATCTAGAGGCGGGGTGCGCTGCCCCCATCGGAGCATTAGCTCAACTCAAGC
CTGTTTCGGGAAAATCCCTACAAGTGTTAACCCTGGATGTTGTAGTGGCTGCTGTCGACGGTTCCCGCACCGTTCGGGAA
CAGGTCAGCGTCGAATTACCCGCGGAGGTCGAACCAGCGCTGGCGGCGGCGCATACGCTGGGGGTGACGGCTGCCGAAGA
GTTACTGGACGATGGTGCCGCCGACGTTGCAGATCTCAAAGCTTCAGGAAGCACTCGATGA

Protein sequence :
MPLWCRRPAELSVNLSDCRLESASVLSATIGNMSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASL
AAMGGIGVFASAIRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASVGTGSPRRA
AQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLARLGHSGAVTEFLDPSVVLPAPAQGALAV
ECRTADSRHGKLAKALARIDDRRTRLAATAERAVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVRE
QVSVELPAEVEPALAAAHTLGVTAAEELLDDGAADVADLKASGSTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-33 41
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-33 41