Gene Information

Name : PPA2318 (PPA2318)
Accession : YP_056980.1
Strain : Propionibacterium acnes KPA171202
Genome accession: NC_006085
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 2516637 - 2518700 bp
Length : 2064 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
GTGGCAACCGAACTGACGTGGACCGACACCGATAGGCTCGCTGTCGACACCGCTCGAGTGCTGGCGGCCGATGCCGTCGA
GAAGACTGGTAACGGTCACCCCGGCACCGCTATTTCCCTAGCGCCGCTGGGCTACCTGCTTTACCACAAGGTCATGTCTA
TCGATCCGTCGGACCCGAATTGGCTCGGACGCGATCGCTTCATCATGTCGGCAGGACATTCCTCGCTGACCCAGTACACC
CAGTTATACCTAGCAGGGCTGGGACTCGAGCTGTCCGACCTGGAGTCCCTGCGTACCTGGGGATCCCTGACCCCCGGCCA
CCCCGAATATGGCTTGACGAAGTTCGTCGAGACCACCACCGGCCCGCTCGGCGCCGGTGTTGCCAACGCCGTCGGCATGG
CCATGGCAGCTCGTCGTGAACGCGGCCTGCTCGACCCGGACGCCGCTCCCGGTACGAGCCTCTTCGACCACTACATTTAC
GCCATTGCCGGTGACGGCTGTATGCAGGAAGGCATTGCATCTGAGGCTTCGTCTCTGGCGGGGACCCAGGAGCTGGGCAA
CCTCATCATGTTCTACGACGACAACCGGATCACCATCGAAGGTGATACCGCCATCGCCTTCTCTGAGAACGTCGAGGCCC
GCTATGAGGCCTACGGTTGGCATGTCCAGCACGTCGATTTCACCAACGGCGGAACGACCTACGAGGAGAATGTCGAAGCC
CTCATGGAGGCCATCGACAACGCCAAGACTGTTACCGACAAGCCGTCTTTCATCCGTCTCACCACCGTCATTGGTTGGCC
GATTCCGAAGCTCGCCGGTCTGGCCCAGGTACACGGTGCGAAGATTGGCGCTGAGGGGGTCAGTGCCCTCAAGGAGAAGC
TTGGCTTTGAAGACAAGCCGTTTGCCATCGACCTTGAGATGGTGCAACAGGTCCGCGCTGCTTTCGCTGAGCGCGGCAAG
GGTCTGCGCGAGGTCTGGGACGAGAAGTTCGCCGCCTGGCATGACGCCAACCCAGACGGCGCTGCCCTGCTCGAGCGGAT
GCTCGCCCACAAGCTGCCCGACGACCTCGACATTCCCACTTTTGAGCCGGGCAAGATGAGCACCCGTAAGGCTTCGGGAG
CGGTCCTGAGCGCTCTGGGTCCGCAGCTTCCCGAGCTGTGGGGCGGATCGGCCGACCTCGCCGGGTCGAACAACACGACC
ATGAAGGGGGCCGACTCCTTCCTGCCTGAAGATCGCTGCTCCGAGAAAGATCCAGGTGGTCCTTACGGGCGTACTATCCA
CTTCGGTGTTCGCGAGCACGCCATGGGTGGCATCCTCAACGGCATCACCTTGGCGGGCCTGACCCGCTGCTACGGCGGAA
CCTTCTTTGTCTTCTCCGATTACATGCGTCCGTCGGTGCGTCTTGCGGCCCTCATGAAGATCCCGTCGATCTTCGTGTGG
ACCCACGATTCTATCGGCGTTGGTGAAGATGGACCCACCCACCAGCCAGTCGAGCACCTAGCCTCCTACCGAGCCATCCC
GGGACTCGACATCGTCCGTCCCGCCGACGCCAACGAGACCGCCGTGGCATGGCGCACCATCGTGGAGCACACCGACCGTC
CCGCCGGCCTAGTGCTGTCGCGTCAGGACCTGCCGACGATTGACCGCAGCAAATACGCCTCTGCCGAAGGCGTCGCCAGG
GGTGCCTACGTGGTTTGCGAGGCTAGCGCCGAGCCCAAAGTCATCCTCATCGGTACTGGGTCCGAGCTGTCGGTGGCCCT
CGAAGCACGCGAGAAGCTTGAGGCCGACGGGATCGCGACCCGCGTCGTCTCGATGCCGTGCCAAGAGTGGTTCGACGAGC
AGGACGAGGAGTACCGCGAGTCGGTGCTACCCAGCTCAGTGACTGCCCGAGTGAGCGTCGAGGCCGGCATCGCCATGGGC
TGGGCAAAGTATGTCGGCTGCAAGGGCGCCTCGGTGTCCCTCGAGCACTTCGGCGCCTCGGCCTCTGGGGCGCTGCTGTT
CGAGAAGTTCGGATTCACCGCTGACCACGTCGCGGAGGTCGCTCACACCGTGTTCATGGAGTGA

Protein sequence :
MATELTWTDTDRLAVDTARVLAADAVEKTGNGHPGTAISLAPLGYLLYHKVMSIDPSDPNWLGRDRFIMSAGHSSLTQYT
QLYLAGLGLELSDLESLRTWGSLTPGHPEYGLTKFVETTTGPLGAGVANAVGMAMAARRERGLLDPDAAPGTSLFDHYIY
AIAGDGCMQEGIASEASSLAGTQELGNLIMFYDDNRITIEGDTAIAFSENVEARYEAYGWHVQHVDFTNGGTTYEENVEA
LMEAIDNAKTVTDKPSFIRLTTVIGWPIPKLAGLAQVHGAKIGAEGVSALKEKLGFEDKPFAIDLEMVQQVRAAFAERGK
GLREVWDEKFAAWHDANPDGAALLERMLAHKLPDDLDIPTFEPGKMSTRKASGAVLSALGPQLPELWGGSADLAGSNNTT
MKGADSFLPEDRCSEKDPGGPYGRTIHFGVREHAMGGILNGITLAGLTRCYGGTFFVFSDYMRPSVRLAALMKIPSIFVW
THDSIGVGEDGPTHQPVEHLASYRAIPGLDIVRPADANETAVAWRTIVEHTDRPAGLVLSRQDLPTIDRSKYASAEGVAR
GAYVVCEASAEPKVILIGTGSELSVALEAREKLEADGIATRVVSMPCQEWFDEQDEEYRESVLPSSVTARVSVEAGIAMG
WAKYVGCKGASVSLEHFGASASGALLFEKFGFTADHVAEVAHTVFME

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 5e-111 45
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 8e-104 42