Gene Information

Name : PPA2219 (PPA2219)
Accession : YP_056881.1
Strain : Propionibacterium acnes KPA171202
Genome accession: NC_006085
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 2404111 - 2405385 bp
Length : 1275 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATCGATCCCAAGCTCCTGCGAACGGATCCGGACGCCGTTCGTCGCTCCCAGGCCGCCCGCGGCGAGGACTCCTCGGT
TGTGGACGACGTTGTCGCCGCAGATGAGGCTCGTCGTGAGGCTATTGCTGCCCATGAGAACCTGCGTGCAGAACAGAAGG
GACTCGGCAAGCGAATCGCTAAAGCATCCGGTGACGAGAAGGCGGAGTTGCTGTCCCGTACTAAGACGATTTCCGGTGAG
GTTGCTGACCTCAAGAAAGCCGCGGACGAGGCAGATGCCAAGTTTACCGAGCTTGCCAAGACTCTCGGCAATATCGTTAT
TGACGGGGTTCCTGCTGGTGGTGAGGATGAAGGTGTCATCAAGGAAACCGTCGGAACTCCCCGCGATTTTGCCGCTGAAG
GGTTCGAGCCTAAGGATCACCTCGAGATCGGTGAAGCCCTCGGCGCTATCGATATGGAGCGCGGCACAAAGATTTCTGGA
TCCCGGTTCTACGTCCTCACCGGCGTTGGCGCTCAGTTGGAATTCGCGCTGCTCAACCTAGCGATGTCTAAAGCGGCTCA
GTGGGGATTCACCCCCATGATCCCGCCGGCCCTCGTCAAGCCGTCGGCTATGGAGGGTACCGGATTCCTCGGTCAAGCTG
CCGATGACGTTTACTACTTACCCAAGGATGACCAGTACCTTGTCGGAACTTCCGAGGTGGCTCTAGCAGCTTTCCATTCT
GACGAGATTCTCGACGATGCCGAGTTGCCCAAACGCTACGTCGCCTTTTCTCCATGCTACCGACGCGAGGCTGGCTCGTA
TGGCAAGGACACCCGCGGTATCTTTCGCGTTCATTGGTTCGACAAAGTCGAGATGTTCGTTTATTGCCTACCGCAGGAGG
CTGAGGCCTGGCATGAGAAGTTGCTGAGTTTCGAGAAGGACTTCATTACCGCGCTACAAATCCCGTTCCAGGTGCTCGAC
GTTGCCTCCGGTGACTTGGGCCTGTCTGCTGCCCGCAAGTTCGATTGTTATGGCTGGCTGCCAACCCAGAACCGCTATCG
TGAGATCACCTCGACGTCGAACTGCACTACCTTCCAGGCCCGGCGCCTGTCTATTCGCCATCGCGGACCTGACGGCGTTG
AACCCCTGGCCACTCTCAATGGCACCTTATGCGCGATGACTCGCATCATCATCATGCTGTTGGAGAACCACCAGCAGGCT
GATGGCTCGGTGCGCATACCCGAGGCACTGCGTCCTTATCTGGGTGGGCGTGAGTTCATTGAGCCTGTGAAGTGA

Protein sequence :
MIDPKLLRTDPDAVRRSQAARGEDSSVVDDVVAADEARREAIAAHENLRAEQKGLGKRIAKASGDEKAELLSRTKTISGE
VADLKKAADEADAKFTELAKTLGNIVIDGVPAGGEDEGVIKETVGTPRDFAAEGFEPKDHLEIGEALGAIDMERGTKISG
SRFYVLTGVGAQLEFALLNLAMSKAAQWGFTPMIPPALVKPSAMEGTGFLGQAADDVYYLPKDDQYLVGTSEVALAAFHS
DEILDDAELPKRYVAFSPCYRREAGSYGKDTRGIFRVHWFDKVEMFVYCLPQEAEAWHEKLLSFEKDFITALQIPFQVLD
VASGDLGLSAARKFDCYGWLPTQNRYREITSTSNCTTFQARRLSIRHRGPDGVEPLATLNGTLCAMTRIIIMLLENHQQA
DGSVRIPEALRPYLGGREFIEPVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-58 42