Gene Information

Name : lysS (PPA0181)
Accession : YP_054897.1
Strain : Propionibacterium acnes KPA171202
Genome accession: NC_006085
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 220963 - 222495 bp
Length : 1533 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGAGTTCTGACACTGCATCCAGCCAGTCCCCTGACGTCTCCGAGCAGATGCAGGTCCGCCTCGACAAGCGGGCCCGGAT
CATCGCTGACGGAGGCCAGGCTTATCCGGTCGATTTGCTACGCGACCACACCCTGGTCCAGGTTCGTCAGAAATACACCG
ACGACACCGGGGAGCTGACCTTGGCGCCTGGCGAGGAGACCACCGATGAGGTCACCGTCGGCGGACGTGTCGTCTTTGTC
CGCAATACCGGCAAACTGTGTTTCGCCAGCTTGCAGGACGGGTTTACCGAGACTTCCAACGGTGAGCGGTTGCAGATCAT
GCTTTCCAAAGCCGAGGTGGGCGATGAGTCCTTGGCTGCGTGGAAGTCCGACGTTGACCTGGGTGACCACGTCTGGGTGC
GTGGCCGAGTCGTCGTCTCTCGTCGTGGTGAGTTATCCATCATGGCTGCTGAGTGGCGGATGGCCTCCAAGGCTCTGCGT
CCGCTGCCGACCCTCCATAAGGAGCTCTCGGAGGAGAGCCGGGTGCGTCGTCGCTACGCGGATCTCGTCGTTCGTGAAGA
GTCTCGCCAGATGGTGCGCACCCGCGCCGTTATCACCCGCGCGGTGCGTCGCGCCCTCGACGAGCGCGGTTTCCTTGAGA
TCGAGACTCCGATCCTGCAGTTGGTCCACGGTGGTGCCGCAGCCCGCCCGTTTAATACCCACCTCAATGCCTTCGACATT
GACATGAGTTTGCGTATCGCTCTTGAGCTCTATCTCAAGCGGACGATGGTCGGCGGCACCGATCGGGTCTACGAGATGGG
TCGGGTCTTCCGCAACGAGGGTATTGATTCCAGCCACTCGGCCGAGTTCTCTATGCTCGAGGCCTACATGAGCTGGGGCA
ACCAATTCACTATTGCTGAGGTGATCAAGGACATCATCATGGCGGTGGCCGACGCCCTCGACGTCCATCAGATTGAGACC
CCCAAGGGCACTATCGACCTCGACGGGCAGTGGCGTTGGGTCAGCGTCTACCCAGGCCTGTCGGAAAAACTAGGGCGTGA
AGTCACCCTTGACACCCCGTTGGAGGAGTTGCAGTCCATCGCCGCTGAGCACGAGATTGAGATCGACCAGTCTTGGGAGG
CCGGCAAGGTCGTTATGGAGCTTTTCGGTGAACTCGTCGAGCCGGGCCTTATCAACCCCACCTTCGTCTGTGATTACCCG
GCTATCGCCCAGCCGCTGGCCCGTCCGCACCGCGACGATCCTCGCATGGTTGAGGCCTGGGACCTCATCATTGGCGGGAT
GGAGCGCGGTACTGGCTTCTCCGAGCTCGTCGACCCAGTCATCCAGCGCGAAGTGCTTACCAAGCAATCCCTCGCTGCTG
CCGCGGGTGACCCTGAGGCGATGCAGCTTGACGAGGACTTCCTCGAGGCCCTGGAATTCGGCTGCCCGCCCATGGGTGGT
CTGGGGCTGGGTGTCGACCGGCTGGTGATGCTCTTTACCAACGCTGGGATCCGCGAGACGATCCTCTTCCCGCTGCTCAA
GCCGGAACACTGA

Protein sequence :
MSSDTASSQSPDVSEQMQVRLDKRARIIADGGQAYPVDLLRDHTLVQVRQKYTDDTGELTLAPGEETTDEVTVGGRVVFV
RNTGKLCFASLQDGFTETSNGERLQIMLSKAEVGDESLAAWKSDVDLGDHVWVRGRVVVSRRGELSIMAAEWRMASKALR
PLPTLHKELSEESRVRRRYADLVVREESRQMVRTRAVITRAVRRALDERGFLEIETPILQLVHGGAAARPFNTHLNAFDI
DMSLRIALELYLKRTMVGGTDRVYEMGRVFRNEGIDSSHSAEFSMLEAYMSWGNQFTIAEVIKDIIMAVADALDVHQIET
PKGTIDLDGQWRWVSVYPGLSEKLGREVTLDTPLEELQSIAAEHEIEIDQSWEAGKVVMELFGELVEPGLINPTFVCDYP
AIAQPLARPHRDDPRMVEAWDLIIGGMERGTGFSELVDPVIQREVLTKQSLAAAAGDPEAMQLDEDFLEALEFGCPPMGG
LGLGVDRLVMLFTNAGIRETILFPLLKPEH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 1e-112 50