Gene Information

Name : thyA (PPA1672)
Accession : YP_056362.1
Strain : Propionibacterium acnes KPA171202
Genome accession: NC_006085
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1826088 - 1826897 bp
Length : 810 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCAGATCTACCTCGACTTGTTGCGGCGGATCCTTGACGAGGGCGTGCGCCGCGAGGACCGTACCGGAACGGGGACGGT
CAGCGTCTTCGGTCACCAGATGGTCTTTGATCTGCGCGAGGGATTCCCGCTGGTAACGACGAAGAAGATTTACACCCGCA
GCGTGTTCGGGGAGTTGCTGTGGTTTCTGCGCGGGGATACGAATGTCGGCTGGCTGCATGATAATAACATCCACATTTGG
GACGAGTGGGCCGACGAGAACGGTGATTTAGGGCCGGTCTACGGGCATCAGTGGCGTTCTTGGCCCGACGACGATGGCAC
AATTGATCAGATCGCCAACGTGGTTGAGCAGATTCGCACCAATCCGTGGTCGCGTCGTCACATCGTCTCGGCATGGAATG
TGGCCGAGATCAAGGAGATGGCCCTGCCGCCGTGCCACACTTTGTTCCAGTTTTACGTCACGCCGGATGATCGGGGAACC
CCGACGTGGTTGAGCTGCCAGCTGTACCAGCGCTCCGGTGACACCTTCCTCGGAGTGCCGTTCAATATCGCGTCATATGC
CCTGCTCACCCATCTGGTGGCCTCGGTGACCGGGCTCAAGCCGTTGCGGTTCGTCCACACCTTGGGTGATGCCCATGTGT
ACCTCAATCACCTCGACCAGGTTCATGAGCAGTTGAAACGTAAGCCGCGGCACCGGCCAACGCTCACCGTCAACCCGGGT
ATCCGTGACATTGACGGGTTTGAGCTGTCCGATATCACCCTGACTGGTTATGACCCGTATCCGGCGCTGCCTGCTCCGAT
TGCGGTCTGA

Protein sequence :
MQIYLDLLRRILDEGVRREDRTGTGTVSVFGHQMVFDLREGFPLVTTKKIYTRSVFGELLWFLRGDTNVGWLHDNNIHIW
DEWADENGDLGPVYGHQWRSWPDDDGTIDQIANVVEQIRTNPWSRRHIVSAWNVAEIKEMALPPCHTLFQFYVTPDDRGT
PTWLSCQLYQRSGDTFLGVPFNIASYALLTHLVASVTGLKPLRFVHTLGDAHVYLNHLDQVHEQLKRKPRHRPTLTVNPG
IRDIDGFELSDITLTGYDPYPALPAPIAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 5e-71 59