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Name : lysS (PPA1621) Accession : YP_056316.1 Strain : Propionibacterium acnes KPA171202 Genome accession: NC_006085 Putative virulence/resistance : Unknown Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 1756085 - 1759447 bp Length : 3363 bp Strand : - Note : catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : GTGACATCGTCCGACCCCGTACCTGAGACACGAGCGGCATCCGCTGCTCGGCCACGCACCGGTTCTCGATCGACCTCGAA TCCAAGGTCCACTCCGGTTGTCGTCATCCCGCGGCTTATGAACATCGCCGCCCTACTCATCGTGTTACGCCTGGTGTTTA GCCGCACCACGTGGGTGGCTATCGCCAACAACGTGTTCTCGTTGTTCATTTTCCCGGTTGACGGTTTCGGTTGGGCCGGT GTCGTGGTCCTGTTGGTGCTGTCGGACGCGCTGTCGCGACGTAAAAGGTTCGCCTGGTGGGTGAGCCTCGTCGTGTTTGG GTTGATGTGGCTGGTGGCGGCCGCGTTCTTTATCATCGTGGTCACCGAGGTTTTCATAGGTTGGCCGACAGACACCCTTA ACGACGTTGATCTGGCGGGGTATCTGTTCAACGTGTTTTCGGTTGGCTGGATCTTGGTGGCATTGTTGACTCATCGTCGC GACTTTGCTGCGCACACGGTTCGCGCCAATCTCGGACGAGCGGTCGTCGTACTCGTTGGCGGTCTGTTGGCTACCGGATT TATTGGGTGGCTATTGGTGTCCCTGACCGGTGGTGTTGGACGGCCACGGAACCGCCTGGTGCACATCATTACTCGCATCC TTCAAGGTAGTGGAGCAGGTATCGCCCAGGAGCCGACGTCGCCGCACTGGGTGCAAGGTGTGGTCTCATTCCTGCTGGCC GTCGTGCTGGTGGCTGCGCTCGTCGTCATTTTGCGTTCCCAACGCAATATCGCGATGATGAGCCTGTCTGACGAGCTGAG ATTACGCCGCCTTCTTGACGAAAATCCGGCTGATTCGCTGGGATATTTTGCCCTGCGCCGTGACAAGGCTGTCGTCTTTT CTCGCAACGGTCATGCCGCCGTCTGTTATCGCACGGAGGCTGGGGTGGCGTTGGCGTCGGGTGACCCAGTTGGCCCGGTT GACCAGTGGCCCGGAGCCATTGACGCATTTCTTGAGGTCGCCCACACCTATGGATGGGTTCCTGCCGTCGTTGGCACCTC AGAGGAAGGTGCGACGACATGGAACCAGGCCGGTTTGAGGGCGATGCGCATCGGCGACGAAGCCATCATCTCCCCGGCTA CGTTTAATCTCGATGATCCTGATCTCAAGCCGGTGCGCCATACGGTCACGAAACTGCGCGCGATGGGATACACGACTCGG GTTCGACGCCATGAGGACATCAATCCGCAGGAGTTGCACAGCCTGATTGACCTGACTGATAAATGGCGTCAAAACGGCGA CGAGCGCGGCTTCTCAATGGCGTTGTCTCGGTTGGGGGACCCTCTAGATGGTCGATGTGTCATGGTGGAGGCGATCTACC CCGACGACGGCCCTCGCGCTGGTCAGACGGCCGGTATTCTGTCCTTTACACCATGGGGTAATGACGGCTTGTCCCTCGAC GTCATGAGGCGAGATCTCGACGGAGCAGATAACGGTGTGACTGAACTTATGGTCGCCGGACTCATGGCGGCCGGGCCAGA AATTGGCATTCGGCGGGTGTCCATGAATTTCGCGGTGTTCCGCGAGGCTATTGAGGAAGGCGCTCGAGTGGGTGCTTCCC CGGTGCGTCGGCTTAACCGCTGGTTGGTACTGGTGGCATCGAAGTGGTTTCAGATTGAGCAGTTGTACCGTTCCAACGTC AAGTACAAGCCGAGCTGGCAGACCCGCTACCTTAATTTCACTGACACCTCTGATCTGGCTCAGGTTGGTCTAGCAATGGG TATTGCTGAGGGTCAGCTCGATATTCCTAATTGGCTTTACCCGGTGGAACCGCCGCCCCAGCCGATATATTCAATTAGCG GGCATCCAGAGATTGCCGAATTCCTGGCTGAAGAACGCGCGCCAATTCTTCCGCAGCGTCGTCTTCCCGAACAGGTTCGT ACTCGAATGGCGACCCGTGAGCGTCTTATTGAGTCGGGGGTGGAGGCCTATCCGCCTGACTGTAAGCCTGACCACCGGCT GGGTGACGTCGCCGTCGAGCTGACTGGCCAGGAGATGACCGTTTCCGGACGGGTGGATGCCTGCCGTGACCACGGCGGGG TCATCTTCGTTGACCTCTTCGACTGGACAGGTGCCTGCCAGCTAGTCATGGAACGTGACACCATGGGCGTCGACAGTCTG CGCGACTTCCGTCATGCGGTGTCTTTGGGAGATCACCTCGTTGCGACTGGAACAGTTGGGGCATCCCGTAACGGGACGCT AAGTCTGGAGATGACGTCGTGGCGGCTAGCAGCGAAGTCGTTGCGACCGCTGCCATCGAGAAGATCGGGATTCAATGACC CAGAGGCCAAGGTTCGTCAGCGTTATCTCGACCTCATCGTCAACCCCAGTGCGCGCGATCAGCTGCGTGCTCGCTCGAAT GCCATCCGCGCGGTGCGAGAAACCCTGCTAAGTCACGACTACATCGAGGTTGAGACGCCGATTCTGCAGACGATCCACGG CGGGGCGAATGCGCGTCCATTCCACACCCACATCAACGCCTACGACCTGGACCTTTATCTGCGCATTGCCCCAGAGCTGT ACCTCAAGAGGCTTATGGTCGGCGGGGCGGGACGAGTTTTCGAGATTGGTAGGAACTTCCGCAACGAGGGTGCCGACGCT ACCCATAATCCCGAATTCACGATGCTCGAGGCCTACCAGGCCTATGGCGATTACGTCCAGATGCGTCACCTCACGAGGGA GATGATCCTGTCCGCAGCCCGCAACGCCACCGGTGGGACGGTCGTGCGCGGACGTGACCGCAAGGGTGTTGAGCATGAGA TCGATTTGGCTAACGAATGGCATGTCATCACTGTCAACGAGGGAATCTCGCGCGGTTTGGGGGAGGAAGTTACTGCCGAT ACCCCCAAAGAGACGCTCATCGGGTACGCCAATAAGCTCGGGATTGCGACTTTGCCGAAGTGGAGTCGAGGCGATGTCGT CCTGGAGTTGCACGAGCACTTGAGTGAGCATGTCACCGTCGAACCGACCTTCTTCTGCGACTTCCCGACCGACGTCTCCC CGCTGACACGACAGCACCGCGATGACCCGCGACTGGCCGAGAAATGGGATCTCATCATCTTCGGCTCCGAGGTGGGTACT GCCTATACGGAACTCGTCGATCCGGTGATCCAACGGGAGCGGTTTACAGCCCAGTCCTTGCTCGCTGCGGGTGGCGATCC GGAGGCGATGGAGCTTGATGAGGACTTCCTGGAGGCTCTCGAGTACGCGATGCCGCCTTCTGGCGGTATGGGCATGGGGC TGGATCGTCTGGTCATGATGCTGACGAATGCGTCAATTCGCGAGACGATTAGCTTCCCGCTGGTGCGTCCGCGCACCTTG TGA Protein sequence : MTSSDPVPETRAASAARPRTGSRSTSNPRSTPVVVIPRLMNIAALLIVLRLVFSRTTWVAIANNVFSLFIFPVDGFGWAG VVVLLVLSDALSRRKRFAWWVSLVVFGLMWLVAAAFFIIVVTEVFIGWPTDTLNDVDLAGYLFNVFSVGWILVALLTHRR DFAAHTVRANLGRAVVVLVGGLLATGFIGWLLVSLTGGVGRPRNRLVHIITRILQGSGAGIAQEPTSPHWVQGVVSFLLA VVLVAALVVILRSQRNIAMMSLSDELRLRRLLDENPADSLGYFALRRDKAVVFSRNGHAAVCYRTEAGVALASGDPVGPV DQWPGAIDAFLEVAHTYGWVPAVVGTSEEGATTWNQAGLRAMRIGDEAIISPATFNLDDPDLKPVRHTVTKLRAMGYTTR VRRHEDINPQELHSLIDLTDKWRQNGDERGFSMALSRLGDPLDGRCVMVEAIYPDDGPRAGQTAGILSFTPWGNDGLSLD VMRRDLDGADNGVTELMVAGLMAAGPEIGIRRVSMNFAVFREAIEEGARVGASPVRRLNRWLVLVASKWFQIEQLYRSNV KYKPSWQTRYLNFTDTSDLAQVGLAMGIAEGQLDIPNWLYPVEPPPQPIYSISGHPEIAEFLAEERAPILPQRRLPEQVR TRMATRERLIESGVEAYPPDCKPDHRLGDVAVELTGQEMTVSGRVDACRDHGGVIFVDLFDWTGACQLVMERDTMGVDSL RDFRHAVSLGDHLVATGTVGASRNGTLSLEMTSWRLAAKSLRPLPSRRSGFNDPEAKVRQRYLDLIVNPSARDQLRARSN AIRAVRETLLSHDYIEVETPILQTIHGGANARPFHTHINAYDLDLYLRIAPELYLKRLMVGGAGRVFEIGRNFRNEGADA THNPEFTMLEAYQAYGDYVQMRHLTREMILSAARNATGGTVVRGRDRKGVEHEIDLANEWHVITVNEGISRGLGEEVTAD TPKETLIGYANKLGIATLPKWSRGDVVLELHEHLSEHVTVEPTFFCDFPTDVSPLTRQHRDDPRLAEKWDLIIFGSEVGT AYTELVDPVIQRERFTAQSLLAAGGDPEAMELDEDFLEALEYAMPPSGGMGMGLDRLVMMLTNASIRETISFPLVRPRTL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lysS1 | YP_005684273.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-157 | 46 |
| lysX | YP_003784331.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-157 | 46 |
| lysS1 | YP_005686365.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-157 | 46 |
| lysS1 | YP_005682181.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 3e-157 | 46 |
