Gene Information

Name : ACIAD0087 (ACIAD0087)
Accession : YP_044888.1
Strain : Acinetobacter sp. ADP1
Genome accession: NC_005966
Putative virulence/resistance : Virulence
Product : UDP-glucose/GDP-mannose dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : 1.1.1.132
Position : 82926 - 84218 bp
Length : 1293 bp
Strand : +
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; Product type pe : enzyme

DNA sequence :
ATGTCTTGTCGCATGCCTCTGGATCTACAAAATCTTCGTATTGCTATCATTGGTTTAGGTTATGTGGGCTTACCGCTGGC
CGTAGAGTTTGGCAAGCATGTATCTGTTGTGGGTTTTGATATCCATCAAAAGCGTGTGGCAGAGCTACAGCAGGGGCAAG
ATCATACCCTTGAAGTGACTCCCGAAGAACTCAAGCAGGCACAGTTGTTAAGTTATTCTTGTGATCTATCGGACTTGAAA
GACTGTAATTTCTTTATTGTGACCGTACCTACCCCAATCGATCAGTTTAAACAGCCTGACTTGACCCCACTAATCAAGGC
TTCACAAAGCATTGGCAAGGTGCTCAAAAAAGACGATATCGTGGTGTATGAGTCGACGGTATATCCGGGTGCCACCGAAG
AAGTCTGTGTCCCTGTACTGGAACAGGTGTCAGGTCTAACTTTCAATCAGGATTTTTTTACAGGCTATAGTCCAGAGCGT
ATTAATCCAGGCGATAAAGCCCACCGCGTGACCAATATTTTAAAAATCACGGCAGGTTCTACACCAGAAGTTGCAGATTA
TGTCGATGCAGTGTACCAATTGATTATTGAAGTGGGTACGCATAAGGCGCCAAGTATTAAAGTCGCAGAAGCAGCAAAGG
TGATTGAAAACACCCAGCGTGATGTCAATATTGCCTTAATCAATGAGCTTGCCATTATTTTTAATAAGATGGGTATCGAT
ACGCAGGATGTGCTTGAAGCCGCAGGAACCAAATGGAATTTCTTGCCGTTTCGCCCAGGTTTGGTGGGTGGACACTGCAT
TGGGGTTGACCCGTATTACCTGACGCATAAGGCTCAGGCGATTGGCTATCATCCAGAGATTATACTGGCAGGGCGTCGTC
TAAACGACAACATGAGTATGTACGTGGCCAATCAGCTCATCAAGAGCATGAACAAAAAGCGCATCCAGATTGAAGATGCC
AAAGTGCTGATTTTAGGCTTAACTTTTAAAGAAAACTGCCCCGATATTCGTAATACCAAAATTGTCGATATTATTAGCGA
GCTTAAAGATTTTAACATGCAGGTCGATGTTTATGACCCATGGGCAGATGCAGAAGAAACGCGTCATGAATATGCGATTG
ATCTGATTGCCGAGCCAGCGCAGGGCAGTTACGATGCCATCATTTTAGCGGTGGCACATCAGCAGTTTAAAGCAATGGGT
GCAGCCGCCATACATGCGCTGGGACGCAGTAACCATGTGATTTATGATCTGAAATATGTGCTGGATCGTCAGCAGTCAGA
TATTCGTCTGTAA

Protein sequence :
MSCRMPLDLQNLRIAIIGLGYVGLPLAVEFGKHVSVVGFDIHQKRVAELQQGQDHTLEVTPEELKQAQLLSYSCDLSDLK
DCNFFIVTVPTPIDQFKQPDLTPLIKASQSIGKVLKKDDIVVYESTVYPGATEEVCVPVLEQVSGLTFNQDFFTGYSPER
INPGDKAHRVTNILKITAGSTPEVADYVDAVYQLIIEVGTHKAPSIKVAEAAKVIENTQRDVNIALINELAIIFNKMGID
TQDVLEAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQAIGYHPEIILAGRRLNDNMSMYVANQLIKSMNKKRIQIEDA
KVLILGLTFKENCPDIRNTKIVDIISELKDFNMQVDVYDPWADAEETRHEYAIDLIAEPAQGSYDAIILAVAHQQFKAMG
AAAIHALGRSNHVIYDLKYVLDRQQSDIRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-144 67
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-144 67
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 1e-112 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ACIAD0087 YP_044888.1 UDP-glucose/GDP-mannose dehydrogenase VFG0431 Protein 5e-145 67