Gene Information

Name : thyA (ACIAD0515)
Accession : YP_045263.1
Strain : Acinetobacter sp. ADP1
Genome accession: NC_005966
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 502907 - 503749 bp
Length : 843 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCGCACCTATTTAGACCTTTTACAACATATCCTCGACAACGGCGGCGACAAAGGTGACCGTACAGGCACAGGGACACG
TTCTGTATTTGGTCATCAAATGCGTTTTGACCTATCTCAAGGGTTTCCTTTACTTACCACCAAGAAAGTACATTTCCGCT
CAATTGTGATTGAGCTGCTGTGGTTTCTCAAAGGCGATACCAACGTTCAATATTTAAAAGACCATAAAGTCAGCATTTGG
GATGAGTGGGCAACGGCAGAGCAAACTGCACGTTTTGGCCGTCCAGAAGGCGAGCTTGGCCCAGTTTATGGACACCAATG
GCGTAATTTCGGTGCTACTCAAAATTCAGATGGGAGCTACAAAAACGACGGTTTTGATCAAATCAAATGGCTCATTAATG
AAATCAAGACCAATCCGAATTCACGTCGCTTGATTGTATCAGGCTGGAATCCAAATGAAGCCGGACAAGTGGCTTTACCA
CCTTGTCATACCCTGTTTCAGTTTTTTGTTCAGGATGGCAAACTCTCTTGTCAGCTCTATCAACGTAGTGCCGATGTGTT
TTTAGGTGTGCCATTTAACATTGCCAGTTATGCCCTTCTCACCCATATGATTGCGCAGGTGTGTGGCCTAGGTGTAGGCG
ATTTTGTCTGGACGGGCGGTGACACCCATTTATACGCCAATCATTTTGAGCAAGCACAACTTCAACTGACACGTGAACCG
TTACCACTTTGTCAGCTTAAATTAAACCCTGAAATTACCGATCTGTTTGATTTTAAATTTGAAGATATTGAAATTGTGGA
TTATCAATCCCACCCTGCAATCAAAGCCCCTGTTGCCGTATAA

Protein sequence :
MRTYLDLLQHILDNGGDKGDRTGTGTRSVFGHQMRFDLSQGFPLLTTKKVHFRSIVIELLWFLKGDTNVQYLKDHKVSIW
DEWATAEQTARFGRPEGELGPVYGHQWRNFGATQNSDGSYKNDGFDQIKWLINEIKTNPNSRRLIVSGWNPNEAGQVALP
PCHTLFQFFVQDGKLSCQLYQRSADVFLGVPFNIASYALLTHMIAQVCGLGVGDFVWTGGDTHLYANHFEQAQLQLTREP
LPLCQLKLNPEITDLFDFKFEDIEIVDYQSHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 1e-67 57
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 6e-66 50