Gene Information

Name : tolC (ACIAD0278)
Accession : YP_045064.1
Strain : Acinetobacter sp. ADP1
Genome accession: NC_005966
Putative virulence/resistance : Resistance
Product : channel-tunnel spanning the outer membrane and periplasm segregation of daughter chromosomes
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1538
EC number : -
Position : 278147 - 279514 bp
Length : 1368 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type m : membrane component

DNA sequence :
ATGACCATCAAAAAAATTATACTTGTGACAGGTTTATGGGGATGCTCTGTTCCTGTTTTTGCACTGGATCTTGTGGGTGT
ATATCAGCTTGCCAAAAATAATGACCCTGCCTTACAGGCCGATCAATATCAATTTCAGGCCGATCAGCTCAATTTAGGCC
TGGCAACAGGGAATTTATTACCCACAGTGACTTTAGCTGGAAATGTTACCCGTGATCGTCAGACGGTTAAAAATGATCAA
TCTTTTGAATTACCTGCTTTTGGTGATGCATCCAATGCATTGGTGAGTAATACTTCTACCAAAAAACAAGTGTCTTTAAC
CGCCAGACAGCCTATCTTTCGTATGGATGCATGGCAAGGCTACAAACAGGTTAAAACATCGGTATTGTTAAGTGAAGTCA
CCTTAAAAATACAAAAACAGCAACATATTCTTGATGTCGCTGAGGCGTATTTTAATGTGCTGCGACAGCAGGCTTTAAGC
GCTGCATATCTGCAGGAAGAGCAAGCCTTGTTGCAGCAGCTTGACATGATGAATGCCAAACTCAAACAAGGATTCGTTGC
AAAAAGTGATGTGAGTGAGGCCAATGCACAATATCAAAATGCACGTGCCAATCGTATTGCTGGAGAAGTACAAATGATGC
TGGCTCAGGAACAATTGAACCAGTATATTGGCGCAAATAGCACACAAAATTTGGCTACACTCAGACCAGATTTTCAATTC
CAGTCTCCGTATCCAGCTCAGTTGCAAGATTGGTTAATGTTAGCTCAGACACATAACTTGGCGATTCAGCAAGCTACATT
GCAACGACAGTATGCCGAGGATGGACGGCGTGTGGAAAAGGCAGCACTTTATCCACAGCTCAACGCAGTTGCCACTTATG
GTTATACCGATCAAAGCCCCGAAACATTGATTTCAACCAATGGTCAGTTTGACCAGATAGGTCTTGAGTTAAGCTGGAAT
GTCTTTAATGGTGGACAAACCCGAACTTCAATTAAAAAAGCCAGTATTTTAATCGATAAGGCCCAATCACAGCTTGATAC
GGCCAAACGCAATGCTTCAGTCGACGTTAAAAAAGCATTTTTACAACTGGAAACAGATCAATCCAAGTTGCAGGCTCGAA
AAGCGGCTATGAGTTCGGCCGAGTTAGTCTCACAGTCGTCTCGTGCCAGTTACAACGAAGGCCTCAAAACTATGGTGGAT
GTTCTTTTGGCACAAAGAAATGCTTTTTCTGCAAAGCAGGATTACTTAAATGCGCAATATGATTATCTGGTCAACGTTTT
AAAACTAAAAGCCGCGGTAGGGCAGCTTTCAGAGCAAGATCTGGCTGAGCTGAATGCATGGTTGATGCCTGAAAAAATAC
AGGACTAA

Protein sequence :
MTIKKIILVTGLWGCSVPVFALDLVGVYQLAKNNDPALQADQYQFQADQLNLGLATGNLLPTVTLAGNVTRDRQTVKNDQ
SFELPAFGDASNALVSNTSTKKQVSLTARQPIFRMDAWQGYKQVKTSVLLSEVTLKIQKQQHILDVAEAYFNVLRQQALS
AAYLQEEQALLQQLDMMNAKLKQGFVAKSDVSEANAQYQNARANRIAGEVQMMLAQEQLNQYIGANSTQNLATLRPDFQF
QSPYPAQLQDWLMLAQTHNLAIQQATLQRQYAEDGRRVEKAALYPQLNAVATYGYTDQSPETLISTNGQFDQIGLELSWN
VFNGGQTRTSIKKASILIDKAQSQLDTAKRNASVDVKKAFLQLETDQSKLQARKAAMSSAELVSQSSRASYNEGLKTMVD
VLLAQRNAFSAKQDYLNAQYDYLVNVLKLKAAVGQLSEQDLAELNAWLMPEKIQD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00321 YP_008207786.1 Outer membrane protein Not tested AbaR25 Protein 1e-135 72
BJAB0868_00325 YP_008211651.1 Outer membrane protein Not tested AbaR26 Protein 1e-135 72

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tolC YP_045064.1 channel-tunnel spanning the outer membrane and periplasm segregation of daughter chromosomes NC_011595.7058144.p0 Protein 5e-136 73
tolC YP_045064.1 channel-tunnel spanning the outer membrane and periplasm segregation of daughter chromosomes NC_010410.6003655.p0 Protein 1e-136 72
tolC YP_045064.1 channel-tunnel spanning the outer membrane and periplasm segregation of daughter chromosomes NC_010400.5987140.p0 Protein 8e-137 72