Gene Information

Name : guaA (ACIAD0151)
Accession : YP_044947.1
Strain : Acinetobacter sp. ADP1
Genome accession: NC_005966
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 150400 - 152052 bp
Length : 1653 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGCTGATTGAAAGAACGTGCGCGATACTTGGAAAAATGCTAGAATATTGCGCTTCTCTCGTTGCCTTGCATAGTTGCGT
AATCATGACAACCAATACTCACATTACTGATGATCGTATCTTAATTCTGGATTTCGGATCTCAATACAGCCAGCTCATTG
CACGTCGTGTACGTGAAGCGGGTGTATATTCTGAAATGTATGCTTTTGATATGTCTGAAGAAGACATTCGTGCATTTAAT
CCAAATGGCATTATTTTGTCAGGTGGGCCTGAAAGCGTGCATGAAGAAGGCAGCCCGCGTGCGCCACAAGTGGTGTTTGA
GCTTGGTGTACCTGTCTTAGGGATTTGTTATGGTTTTCAAACCATGTCTGAGCAGTTGGGCGGAAAAGTTGAGCCTGGTA
CTGTACATGAGTTTGGCTATGCCGAAGTGGATATTCAGCAGCGCGACCAACTTGTTGGAAACTTGCAAGATCGTGAGAAT
CAACTGCATGTCTGGATGAGCCATGGCGACAAAGTTAGTCGTTTACCAGAAGGTTTTAGTACCACTGCAAGTACCCCAAG
CTGTCCATTCGCAGCAGCATCGGATGAAGCTCGCCGTTTTTACGGTGTGCAGTTCCATCCTGAAGTCACGCATACAGCGA
AAGGTGCCGAGTTACTGGCAAACTTTGTGCATAAAATCTGTGGTTGTGGCGGTCTTTGGACACCAGAACACATTATCGAT
TTGCGTGTAGAACAGTTACGCGCCCAAATTGGTGACGAAAAAGTTTTACTTGGCCTATCGGGTGGTGTGGATTCATCTGT
CGTTGCTGCATTGTTGCATAAAGCCATTGGTGATCAGTTGACTTGCGTATTTGTGGACAATGGTTTGCTTCGTTTAAACG
AAGGTGACCAAGTGATGCAAATGTTTGCTGATAACATGGGGATTCGTGTGATCCGTGCAGATGCAGAAGAACGTTTCTTG
ACTGCGCTTGCAGGTGAAGTTGATCCTGAGAAAAAACGTAAGATCATTGGTCGTGAATTTATTGAAGTATTTGCAGAAGA
AGCACGCAAACTGGATGGCGTGAAATTCTTGGCACAAGGTACGATTTATCCTGACGTGATTGAATCTGCTGCAAGCAAAC
AGGGTAAAGCACACGTGATTAAATCACACCATAATGTGGGTGGTTTACCTGATGATTTAGAATTTGAATTGGTTGAGCCA
TTACGTGATTTATTCAAAGATGAAGTGCGTAAATTGGGTACCACACTCGGCTTGCCGCACAGCATGATTTACCGTCATCC
GTTCCCAGGTCCAGGTTTGGGCGTGCGTATTTTGGGTGAAGTGAAAAAAGAATATGCAGATATTCTTCGCCTTGCCGATG
ACATCTTTATGCAAGAGCTTCGCGCAAGTGGTTGGTATGACAAAACTGCGCAAGCCTTTGCAGTATTCCAACCTGTAAAA
TCTGTGGGTGTGGTCGGTGATGGTCGTCGTTATGCATGGGTGATCGCACTTCGTGCAGTTGAGACTGTTGACTTTATGAC
AGCGCGTTTCGCTCACTTGCCATACGAGTTGGTGGATAAAATCTCAACCCGTATCATGAATGAAATCAAAGATGTTTCAC
GTGTTGTGTATGACGTGTCATCTAAGCCACCAGCAACGATTGAGTGGGAGTAA

Protein sequence :
MLIERTCAILGKMLEYCASLVALHSCVIMTTNTHITDDRILILDFGSQYSQLIARRVREAGVYSEMYAFDMSEEDIRAFN
PNGIILSGGPESVHEEGSPRAPQVVFELGVPVLGICYGFQTMSEQLGGKVEPGTVHEFGYAEVDIQQRDQLVGNLQDREN
QLHVWMSHGDKVSRLPEGFSTTASTPSCPFAAASDEARRFYGVQFHPEVTHTAKGAELLANFVHKICGCGGLWTPEHIID
LRVEQLRAQIGDEKVLLGLSGGVDSSVVAALLHKAIGDQLTCVFVDNGLLRLNEGDQVMQMFADNMGIRVIRADAEERFL
TALAGEVDPEKKRKIIGREFIEVFAEEARKLDGVKFLAQGTIYPDVIESAASKQGKAHVIKSHHNVGGLPDDLEFELVEP
LRDLFKDEVRKLGTTLGLPHSMIYRHPFPGPGLGVRILGEVKKEYADILRLADDIFMQELRASGWYDKTAQAFAVFQPVK
SVGVVGDGRRYAWVIALRAVETVDFMTARFAHLPYELVDKISTRIMNEIKDVSRVVYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-139 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-139 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-139 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-116 50