Gene Information

Name : metC (BT9727_3997)
Accession : YP_038316.1
Strain : Bacillus thuringiensis 97-27
Genome accession: NC_005957
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 4062444 - 4063556 bp
Length : 1113 bp
Strand : +
Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity

DNA sequence :
ATGTCAACTATCGAAACAAAACTAGCGCAAATCGGAAACCGGAGTGAAACTACAACAGGAACTGTTAATACGCCTGTTTA
CTTTTCAACTGCTTATCGTCACGAAGGGATTGGTAAATCTACTGGATTTGACTATTCACGAACTGGAAACCCAACTCGCG
GCCTATTAGAACAGGCAATCGCAGACTTAGAATACGGCGAACAAGGTTATGCCTGTAGTTCCGGTATGGCAGCTGTGCTC
CTTGTCCTTTCCCTATTCCGCTCCGGAGACGAACTTATTGTATCCGAAGATTTATACGGGGGCACTTATCGATTATTTTC
TGAGCACGAAAAAAAGTGGAATGTTCGATGTAGATACGTAAATACACAATCTATTAAACAAATTGAGCAAGCTATCACAA
CTGAAACGAAAGCTATTTTCATAGAAACCCCGACAAATCCATTAATGCAAGTTACTGATATTGCCGCTGTCGCAACTGTA
GCAAAAAGACACGGACTACTTCTTATTGTAGACAATACATTCTACACGCCTTATATACAGCAGCCATTAACAGAAGGTGC
TGACATTGTACTTCATAGCGCAACAAAATATTTAGGAGGACATAACGATGTACTAAGCGGACTTGTCGTTGCAAAAGGAA
AGGAACTTTGTGAGGAAATCGCCCATTATCATAATGCATCAGGTGCGGTCTTAAGTCCATTTGACTCATGGCTATTAATC
CGTGGTATGAAAACGTTAGCGCTTCGCATGAGACAACATGAAGAAAATGCAAAAGCAGTTGTTGCTTATTTAAATGATGA
GGACGGGGTGACAGATGTATTTTATCCTGGAAGAGGCGGCATGATTTCATTTCGTCTTAAAGATGAAACATGGATTAATC
CATTCTTACAATCTTTATCCTTAATTACATTCGCCGAAAGTCTTGGTGGTGTTGAAAGTTTAATGACATATCCAGCAACA
CAAACACACGCTGATATTCCTGAAGAAATCAGAACAGCAAACGGTGTATGTAATCGTCTTCTTCGATTTTCTGTTGGCAT
TGAAAATAGTAACGATTTAATTCAAGACTTACAGCAAGCCATTAAACTTGTAAAAGAAGGTGTAAGAATATGA

Protein sequence :
MSTIETKLAQIGNRSETTTGTVNTPVYFSTAYRHEGIGKSTGFDYSRTGNPTRGLLEQAIADLEYGEQGYACSSGMAAVL
LVLSLFRSGDELIVSEDLYGGTYRLFSEHEKKWNVRCRYVNTQSIKQIEQAITTETKAIFIETPTNPLMQVTDIAAVATV
AKRHGLLLIVDNTFYTPYIQQPLTEGADIVLHSATKYLGGHNDVLSGLVVAKGKELCEEIAHYHNASGAVLSPFDSWLLI
RGMKTLALRMRQHEENAKAVVAYLNDEDGVTDVFYPGRGGMISFRLKDETWINPFLQSLSLITFAESLGGVESLMTYPAT
QTHADIPEEIRTANGVCNRLLRFSVGIENSNDLIQDLQQAIKLVKEGVRI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-72 46
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-73 45