Gene Information

Name : thyA (BT9727_2020)
Accession : YP_036349.1
Strain : Bacillus thuringiensis 97-27
Genome accession: NC_005957
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2106204 - 2107160 bp
Length : 957 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACATGCTGAAAATGAATACTTAAATTTATGCCGCCATGTAATGGAGCATGGTACGAAGAAAGAAGATCGTACAGG
GACAGGCACTGTATCTGTATTTGGATATCAAATGCGTTTTGATTTAAGTAAAGGTTTTCCTTTATTAACGACAAAGAGAG
TGCCGTTTCGCCTTGTAGCAAGTGAATTGCTTTGGTTTATGAAAGGTGATACAAATATTCGTTATTTATTGCAGCATAAT
AATAATATTTGGAATGAATGGGCATTTAAGAGCTGGGTAGAAAGTGACGAGTATACTGGTCCTGACATGATTGATTTCGG
TCTTCGCTCACAACAAGATGAAGAATTTAAAGTACAGTACGATGAGCAAATGGAATTGTTTAAAAAGAACGTTTTAGAAG
ATGATGAGTTCTCAAATAAATATGGTTATTTAGGAGACGTATACGGTAAGCAGTGGCGTGCTTGGAAAACGACAGCTGGT
GAGACACTTGATCAATTAAAAGATGTAATTGAAATGATTAAGAAAACGCCAGATTCGCGTCGTCTAATTGTTTCTGCTTG
GAATCCTGAAGATGTACCAAGTATGGCATTACCACCTTGTCATACGTTATTCCAATTTTATGTAGCAGATGGCAAACTTT
CTTGTCAGCTATATCAAAGAAGTGGTGACATATTCCTTGGAATTCCATTTAACATTGCAAGTTACTCACTACTGACACAT
TTAATTGCACATGAATGCGGACTTGAAGTGGGAGAATTTGTTCATACAATTGGAGATGCACACATTTATACGAATCATTT
TGAGCAAGTAGAAAAGCAATTGGCACGTGAACCACGTCCATTCCCGAAACTTACACTAAATCCAGATGTGAAATCTGTGT
TTGATTTTGAAATGGAAGATTTAACAATTGAAGGATATGATCCACATCCAGCAATTAAAGCACCAGTTGCAGTGTAA

Protein sequence :
MKHAENEYLNLCRHVMEHGTKKEDRTGTGTVSVFGYQMRFDLSKGFPLLTTKRVPFRLVASELLWFMKGDTNIRYLLQHN
NNIWNEWAFKSWVESDEYTGPDMIDFGLRSQQDEEFKVQYDEQMELFKKNVLEDDEFSNKYGYLGDVYGKQWRAWKTTAG
ETLDQLKDVIEMIKKTPDSRRLIVSAWNPEDVPSMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYSLLTH
LIAHECGLEVGEFVHTIGDAHIYTNHFEQVEKQLAREPRPFPKLTLNPDVKSVFDFEMEDLTIEGYDPHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 1e-105 65