Gene Information

Name : guaA (BH01820)
Accession : YP_033036.1
Strain : Bartonella henselae Houston-1
Genome accession: NC_005956
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 250364 - 251920 bp
Length : 1557 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCATATCACATTCAGACACTGTTCTTATTATTGATTTTGGTTCACAAGTTACACAGCTTATCGCACGGCGAGTAAG
AGCGATGGGTGTCTATTGTGAAGTTGTTCCTTTTCAATTAGCTTTAGAGGGCATGCAAAGGATAAAACCAAAAGCTGTTA
TTTTATCAGGCAGTCCTTATTCCGTTATTGATGAAGGTTCACCGCGTGCTCCGATGGAAATTTTTGAAATGGATATTCCA
GTTCTTGGTATTTGTTATGGTCAACAAATCATGTGCGTTCAGCTTGGTGGAAAAGTTGCATCAGGACATGAGCGTGAATT
TGGGCGGGCTTTTTTAGAGGTACAAGAAAACAGTGCACTTTTTGAGGGTGTTTGGGAAAAAGGCTCTTGTTATCAAGTAT
GGATGAGTCATGGTGATCGCGTGACGGCTTTACCAGAGGGGTTTCGTGTTATAGGGACCTCAAAAGGCGCTCCCTATGCT
GCTATTGCTGATGAGAAAAGGCGCCTTTACGCAGTGCAGTTTCATCCTGAAGTTGTCCATACGTTAGATGGTACAAAACT
TTTGCAAAATTTTGTTCTTAAAATCTCTAATCTTAAAGGCAATTGGTCAATGGCTTCTTATCGTGAGCAGACAATTGCTA
AGATACGGCAAAAAGTAGGAAAAAGTCGTGTCATCTGTGGTCTTTCAGGTGGTGTGGATTCATCAGTTGTGGCAGTGCTC
CTTCATGAAGCAATAGGAGATCAACTGACATGTATTTTGGTAGACCATGGGTTGATGCGCAAAAATGAGGCTCAAGAAGT
TCTTACATTATTCCGAGATCATTATAATATAAAGCTTATTCATGTTAATGCCGCCAATATGTTTCTCAATGCTCTAGAAG
GTGAGATAGATCCAGAAAAAAAGCGCAAAACGATAGGCCGCCTTTTCATTGAAGTTTTTGAAGAAGAAACCAAAAAGATT
GGCGGTGCAGAATTTTTAGCGCAGGGCACGCTTTATCCAGATGTCATTGAGAGTATATCAGCTATTGGTAAATCGGTAAC
AATTAAAAGCCATCATAATGTAGGGGGATTACCGGAGCGGATGAACATGAAACTTGTAGAGCCATTGCGTGAGCTATTTA
AGGATGAAGTTCGTTCTCTAGGGAAAGAGTTAGGATTGCCAGAGCAGTTTATCGGCCGTCATCCTTTTCCAGGTCCTGGT
CTTGCAATTCGGTGCCCAGGTGCAGTGACACGTGAAAAGTTAGAAATTCTACGTGAAGCGGATGCTATTTACCTTGATGA
AATCCGTAAAGCCGGTCTTTATGACGAAATTTGGCAGGCATTTGCTATTCTTCTGCCTGTTCAAACTGTCGGGGTTATGG
GTGATGGACGTACTTATGAATTTGTTTGTGCTCTTCGTGCAGTAACATCTGTAGACGGAATGAGCGCTGATTTTTATCCC
TATGATATGGAGTTTTTAAGCAAAACAGCAGCACGTATTATTAACGAAGTGAGAGGTATTAATCGTGTTGTTTATGATGT
AACGTCAAAACCTCCTGGCACTATTGAGTGGGAATGA

Protein sequence :
MSISHSDTVLIIDFGSQVTQLIARRVRAMGVYCEVVPFQLALEGMQRIKPKAVILSGSPYSVIDEGSPRAPMEIFEMDIP
VLGICYGQQIMCVQLGGKVASGHEREFGRAFLEVQENSALFEGVWEKGSCYQVWMSHGDRVTALPEGFRVIGTSKGAPYA
AIADEKRRLYAVQFHPEVVHTLDGTKLLQNFVLKISNLKGNWSMASYREQTIAKIRQKVGKSRVICGLSGGVDSSVVAVL
LHEAIGDQLTCILVDHGLMRKNEAQEVLTLFRDHYNIKLIHVNAANMFLNALEGEIDPEKKRKTIGRLFIEVFEEETKKI
GGAEFLAQGTLYPDVIESISAIGKSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRSLGKELGLPEQFIGRHPFPGPG
LAIRCPGAVTREKLEILREADAIYLDEIRKAGLYDEIWQAFAILLPVQTVGVMGDGRTYEFVCALRAVTSVDGMSADFYP
YDMEFLSKTAARIINEVRGINRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-138 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-138 56
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-138 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-116 50