Gene Information

Name : thyA (BQ08630)
Accession : YP_032478.1
Strain : Bartonella quintana Toulouse
Genome accession: NC_005955
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1015538 - 1016332 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAAACTTACCTCGATCTTTTATCTCATGTTTTAAATAAGGGCATTGATCGTACAGACCGAACTGGTGTTGGGACGCG
ATCGGTTTTTGGCTATCAGATGCGGTTTGATTTACAGATCGGATTTCCATTGTTAACAACGAAGAAATTGCATTTACGCT
CGATCATTTATGAACTTTTGTGGTTTCTTAGAGGTGATACAAATGTCGCATGGTTAAAAGAACATGGTGTATCAATTTGG
GATGAGTGGGCTGATGAAAAAGGCAATCTTGGTCCTATTTATGGTTATCAATGGCGTTCTTGGCCAGCTTCTGATGGACG
CTATATTGATCAAATCAGTCGTCTTTTAACGATGATTAAAAAAACACCTGATTCTCGTCGCTTGATTGTCTCTGCGTGGA
ATCCTGCATTGATAGAAGAAATGGCTTTGCCACCTTGTCATTGCTTTTTTCAATTTTATGTTGCCGACGATAAGTTGTCT
TGCCAGCTTTATCAGCGTTCGGCGGATATTTTTTTAGGTGTTCCGTTCAATATTGCTTCTTATGCGTTGTTAACGATGAT
GATTGCGCAAGTGAGTGGCCTTAAAGCCGGTGATTTCATTCATACTCTCGGCGATGCCCATCTTTATTCTAATCATTTTG
AACAGGCTCGATACCAATTATCTCGTATACCAAATGCTTTGCCATCGATGCTTATAAATCCATCGGTAACAGATCTTTTT
TCGTTTAAATTCGAGGATTTTGAATTGCTTAATTATGAAGCGCAACCACATATAAAGGCACCGGTAGCAGTATGA

Protein sequence :
MKTYLDLLSHVLNKGIDRTDRTGVGTRSVFGYQMRFDLQIGFPLLTTKKLHLRSIIYELLWFLRGDTNVAWLKEHGVSIW
DEWADEKGNLGPIYGYQWRSWPASDGRYIDQISRLLTMIKKTPDSRRLIVSAWNPALIEEMALPPCHCFFQFYVADDKLS
CQLYQRSADIFLGVPFNIASYALLTMMIAQVSGLKAGDFIHTLGDAHLYSNHFEQARYQLSRIPNALPSMLINPSVTDLF
SFKFEDFELLNYEAQPHIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 4e-77 61