Gene Information

Name : nrdF (BQ01830)
Accession : YP_031892.1
Strain : Bartonella quintana Toulouse
Genome accession: NC_005955
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 237545 - 238519 bp
Length : 975 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGACAAAGATTACAACTAAAAATCCTGTTGTTTGTGCTGTCAATTGGAATAGATTGCATGATGAAAAAGATCTTGAAGT
TTGGAACCGCTTAACTGGAAATTTTTGGTTACCTGAGAAGGTGCCACTTTCCAATGATATTCCTTCATGGGCAAGTCTAA
CAGAGGAAGAACGCAAGCTAACAGTTCGTGTTTTTACGGGGTTAACTCTCTTGGATACGATTCAAAACACCGTAGGAGCC
ATTTCGCTTATGGCTGATGCAATAACAGAGCATGAGGAGGCGGTGTTGACGAATATTGCGTTCATGGAAGCCGTTCATGC
ACGTTCTTATTCCTCTATTTTTTCAACTTTGTGTTCAACGGTAGAAGTCGATGATGCTTTTAGGTGGTCAGAAGAAAATA
TTCATTTGCAGAAAAAGGCTAGGTTAGTGCTTGAGCGTTATGAAGCGAGCGATCCACTAAAGAAGAAAATTGCTTCAACT
TTACTTGAAAGCTTTTTATTTTATTCTGGTTTTTATTTACCCATGTATTGGGCTAGTCGTGCTAAATTGACCAATACAGC
TGATCTCATTCGGCTTATTATTCGTGATGAAGCTGTACATGGTTATTATATAGGCTATAAATTTCAATTAGGGTTTGCAA
AACTTAATGAAAGTAAAAAGCAGGAAATTAAAGATTTTTCTTTTAACTTACTCTTCGACCTTTATAATATTGAATGTAAA
TATACTGAAGATCTTTATGATGCACTTGGGTTGACAGAAGATGTTAAAGTTTTTCTTCATTATAATGCGAATAAGGCCTT
AATGAATCTAGGTTTTGAACCTCTTTTCCCTCCTGAGGTTTGTCGTGTTAATCCCGCTATTTTGGCAGCTTTGTCACCGA
GCTCTGATGAAAATCATGACTTCTTTTCAGGAGCTGGCTCTTCTTATGTTATTGGCAAGGCGGTTGCTACCACGGATGAC
GATTGGGAATTTTAA

Protein sequence :
MTKITTKNPVVCAVNWNRLHDEKDLEVWNRLTGNFWLPEKVPLSNDIPSWASLTEEERKLTVRVFTGLTLLDTIQNTVGA
ISLMADAITEHEEAVLTNIAFMEAVHARSYSSIFSTLCSTVEVDDAFRWSEENIHLQKKARLVLERYEASDPLKKKIAST
LLESFLFYSGFYLPMYWASRAKLTNTADLIRLIIRDEAVHGYYIGYKFQLGFAKLNESKKQEIKDFSFNLLFDLYNIECK
YTEDLYDALGLTEDVKVFLHYNANKALMNLGFEPLFPPEVCRVNPAILAALSPSSDENHDFFSGAGSSYVIGKAVATTDD
DWEF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 4e-105 67