Gene Information

Name : hemC (BAS4361)
Accession : YP_030608.1
Strain : Bacillus anthracis Sterne
Genome accession: NC_005945
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 4272282 - 4273211 bp
Length : 930 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCGCAAAATTATTGTAGGGTCACGAAAGAGTAAATTAGCATTAACGCAAACAAACTGGTTTATTGATCAGTTAAAAGC
GCTAGGTTTACCATATGAATTTGAAGTGAAAGAAATCGTCACAAAAGGTGATGTTATTTTAGATGTTACTCTTTCAAAAG
TAGGCGGAAAAGGTTTGTTTGTGAAAGAGATTGAACATGCGTTACTTACGAAAGAAATTGATATGGCTGTACATAGTATG
AAAGATATGCCGGCCGTACTTCCAGAAGGATTAATGATCGGTTGTACACCAAAGCGTGTTGACCCTCGTGATGCTTTTAT
CTCAAAAAGTGGAGCGTCGTATAAAGAGTTAGCAGAAGGCGCTATTTTAGGTACGAGTAGTTTAAGACGTAGTGCACAGC
TGCTCGCTGCAAGACCAGATTTACAAGTGAAGTGGATTCGCGGAAATATCGATACACGTTTACGCAAATTAAAAGAAGAA
GATTACGATGCAATTATTTTAGCGACGGCGGGATTACAAAGAATGGGCTGGGATAATGAAGTTATTACAGAACATTTAGA
TGAGACGTTATGTGTACCTGCTGTAGGACAAGGCGCATTAGCGATTGAGTGTCGTGAGGATGATAAGGATTTACTACAGT
TGTTAGCGCATATAAATGATGCAGTAACAGAGAAAACAGTGGCAGCAGAACGAGTATTTCTTCATAAACTTGAAGGTGGA
TGCCAAGTTCCGATCGCTGGATATGCAACTATTACAGAAAACGATGCAATCGAATTAACAGCTCTTGTCGGGTCTATGGA
TGGTTCTGTTTTATTGAAAGAGACAGTAGTAGGAACTGATCCAGAGAAAGTAGGATTAGAGGCTGCGGACCGTTTAATTA
AGCAAGGCGCAAAAGAACTCATTCTTGCTGCAAATAAGGGGCAACAATAA

Protein sequence :
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLFVKEIEHALLTKEIDMAVHSM
KDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASYKELAEGAILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEE
DYDAIILATAGLQRMGWDNEVITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATITENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKELILAANKGQQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-57 47
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-57 47