Gene Information

Name : guaA (BAS0254)
Accession : YP_026538.1
Strain : Bacillus anthracis Sterne
Genome accession: NC_005945
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 260912 - 262459 bp
Length : 1548 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGATTATTTTGAAGAAGCAACACGATACAATTATCGTTTTAGATTTTGGAAGTCAATACAATCAGTTAATAGCACGTCG
AATTCGTGAGTTCGGTGTATACAGTGAGCTTCATCCACATACAATTACTGCGGAAGAAATTAAAGCAATGAATCCAAAAG
GGATTATCTTCTCTGGTGGACCAAATAGTGTATACGGTGAAGGCGCATTACATTGTGATGAAAAAATCTTTGACCTAGGA
TTACCGATCTTCGGTATTTGTTACGGTATGCAACTTATGACGCAACAATTCGGTGGTACAGTAGAGCGTGCAAACCACCG
TGAGTACGGAAAAGCTGTTCTGAAAGTAGAGAACGAGTCAAAATTATATGCGAACCTTCCAGAAGAGCAAGTTGTATGGA
TGAGTCATGGCGACTTAGTAACTGGTTTACCTGAAGGATTCGTAGTAGACGCGACAAGTGAGTCTTGCCCAATTGCTGGT
ATGAGCAATGAAGCGAAAAACTTATACGGTGTACAATTCCACCCAGAAGTACGTCACTCTGAGCACGGTAACGATTTAAT
TAAAAACTTCGTATTCGGCGTATGTGGCTGTTCTGAAGGATGGAACATGGAGAACTTTATTGAAGTAGAACTAGAGAAAA
TCCGTGAAACTGTTGGAGACAAAAAAGTACTATGTGCGCTTAGCGGCGGTGTAGATTCTTCTGTTGTAGCAGTATTAATT
CATAAAGCAATCGGCGATCAGTTAACATGTATTTTCGTTGACCATGGTTTACTTCGTAAAGGCGAAGCAGAAGGTGTTAT
GAAAACATTTAGCGAAGGCTTCCACATGAACGTTATTAAAGTGGATGCAAAAGAACGCTTCATGAACAAGTTAAAAGGTG
TAGAAGATCCAGAACAAAAACGTAAAATTATCGGTAACGAATTCATTTACGTATTTGATGATGAAGCTTCTAAATTAGAA
GGAATGGACTTCTTAGCACAAGGTACACTGTACACAGATATCGTTGAAAGTGGTACAGCAACTGCACAAACAATTAAATC
TCACCATAACGTTGGTGGACTTCCAGAAGACATGCAGTTCAAATTAATTGAGCCTTTAAACACGTTATTTAAAGATGAAG
TACGTGTATTAGGATCTGAACTAGGAATTCCTGATGAGATCGTATGGCGTCAACCATTCCCAGGTCCTGGTCTTGGTATT
CGTGTACTAGGTGAAATCACGGAAGAGAAATTAGAAATCGTTCGTGAATCTGATGCGATTTTACGTGAAGAAATTATTAA
AGCAGGCTTAGACCGCGAAATCTGGCAATACTTCACTGCGCTTCCTGGTATGCGTAGCGTAGGTGTTATGGGTGACGAGC
GTACTTACGATTACACAGTGGGTATCCGTGCAGTAACATCTATCGACGGTATGACAGCTGACTGGGCACGTATCCCTTGG
GACGTATTAGAGAAAATCTCTGTACGTATCGTAAACGAAGTGAAACACGTTAACCGTATCGTGTATGATGTAACGAGTAA
GCCACCAGCAACTATTGAGTGGGAATAG

Protein sequence :
MIILKKQHDTIIVLDFGSQYNQLIARRIREFGVYSELHPHTITAEEIKAMNPKGIIFSGGPNSVYGEGALHCDEKIFDLG
LPIFGICYGMQLMTQQFGGTVERANHREYGKAVLKVENESKLYANLPEEQVVWMSHGDLVTGLPEGFVVDATSESCPIAG
MSNEAKNLYGVQFHPEVRHSEHGNDLIKNFVFGVCGCSEGWNMENFIEVELEKIRETVGDKKVLCALSGGVDSSVVAVLI
HKAIGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFHMNVIKVDAKERFMNKLKGVEDPEQKRKIIGNEFIYVFDDEASKLE
GMDFLAQGTLYTDIVESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRVLGSELGIPDEIVWRQPFPGPGLGI
RVLGEITEEKLEIVRESDAILREEIIKAGLDREIWQYFTALPGMRSVGVMGDERTYDYTVGIRAVTSIDGMTADWARIPW
DVLEKISVRIVNEVKHVNRIVYDVTSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 74
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 74
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 74
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-139 55