Gene Information

Name : clpB (pc0728)
Accession : YP_007727.1
Strain : Candidatus Protochlamydia amoebophila UWE25
Genome accession: NC_005861
Putative virulence/resistance : Virulence
Product : endopeptidase Clp ATP-binding chain
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 883222 - 885828 bp
Length : 2607 bp
Strand : -
Note : strongly similar to endopeptidase Clp ATP-binding chain

DNA sequence :
ATGAATCAAAATTTCACAGATCATGTTGCGGAAGCTATTCAAGCCGCTTTTGCAGAAGCACAACGTTTAAATCACACAGA
AGTTACTGAAAATCACCTGCTATGGGCTTTTCTCAAAGATAAAGAAGGATATTTTTACTCGCTTTTAAATGGGCTGGGGA
CAAATCCGCAAAAATTATTTCAAGAGACTGAAAACAATATTCACCATTTACCAACTTACTCGGGTGGAGGGCAAGCCCCA
AATCCTTCCAGAAGCCTACAAAGTCGCATTGTCGATGCTCAAAATATCGCTCAAAGCTGGAAAGATACTTATACGAGCAG
CGATCATTTTTTAATCTCTTATTGGAAAAATGGTGGAGATCCTTTTGCTTCTTGGAAAAAGAAAACTACTATCTCTTTAG
AAAAGCTGGAAGAACAAATAAAAAAAATTCGAGGTGATCGTCATATGGACTCTCCTAGCTCCGAATCAAATTTACAAGCT
CTAGAAAAATATTGCAAAAATCTCACAGATCTGGCTCGTCAAGGTAAGCTCGACCCTGTGATTGGAAGAGATGAAGAAAT
TAGACGAACCATGCAAGTTTTGTGTAGACGAACCAAAAATAATCCTATGCTTATTGGAGATCCGGGAGTTGGTAAAACAG
CGATTGCTGAAGGATTAGCTCAACGCATAGTCCAGCAAGATATTCCCGATTCTTTAAAAAATAAACAGCTACTTGCGTTG
GATATGGGAAGTTTAATTGCCGGTACAAAGTACCGAGGAGAATTTGAAGAAAGGCTGAAAGGTATTTTACAAGACATTGA
GAAAAGCGAAGGGCAGATCATCCTTTTTATTGATGAAGTGCATACTTTAATTGGAGCTGGCGCGACAGATGGAGCGATGG
ATGCCGCCAATTTATTGAAACCCGCACTTGCGAGAGGTATTTTACATTGCATCGGAGCGACTACCCTTAACGAATATCAA
AAATACATTGAAAAGGATGCTGCTCTTGAAAGACGCTTTCAACTTGTCTTAGTTAATGAACCAACTATAGAAGACTCGAT
TGCAATTTTGAGAGGTTTAAGAGAAAGATATGAAATTTACCATGGGGTGCATATCACAGAGTCTGCGATCCACGCTGCCG
TGTTATTGTCTTCTCGCTACATTACAGATCGTCGTCTGCCCGACAAAGCAATCGATTTGATCGACGAATCAGCTAGCTTA
ATTCGTATGCAACTCGGAAGCCGCCCTCTTCCCATCGACAATAAAGAACGAGAGCTGGCGGGCCTAATTGTGGAACAAGA
AGCGATGAAACGAGAAAGCACTCCCCTAGCTAAAAATGAAGTAGAAAAATTAGAAGGGCGCATTGCTCAAATCAAGGAAG
AACTGAAAATTTTACGTGAGCAATGGGATCAAGAGAAAAAAATTATCGAATCTTTAAAAGAGAAAAAAGACAAACTTGAG
AAATTGCGTTTTGAAGAAGAAGCTGCAGAACGTAAAGCCGACTATAACCGTGTAGCAGAGCTGCGCTACAATTTGATCCC
TCAACTACAAAAAGAGATTGAAGAGGCACAGACTCAGCTTAATAACAAACCTAATAGACTTTTGCAGGAAGAAGTAGACG
AGTCCCTCATTGCTCAAATCGTTTCTAAATGGACGGGTATCCCCGTTCATAAAATGTTAGAGGGTGAAGCTGAGCGTCTC
TTACATCTTGAAAACGAACTTGAAAAAAGAGTTGTTGGTCAAGAAATAGCTGTTTCAGCTGTGAGTGAAGCAATTCGTCG
TTCAAGGTCTGGACTAAGTGATCCTAATCGGCCAATGGGTGTTTTTCTTTTCCTGGGTCCGACAGGCGTTGGCAAAACAG
AGCTTGCTAAAGCGTTAGCTTTTCAATTGTTTAACCAAGATGAAGCATTGATTCGGCTAGACATGTCTGAATACATGGAA
AAACACACGGTTTCTAAATTGATTGGCTCCCCTCCCGGGTATATTGGGTATGAGGAAGGAGGGCAATTAACAGAGGCGCT
GCGAAGAAGGCCTTATGCCGTTGTTCTGTTTGATGAGATTGAAAAAGCTCACCCTGATGTATTTAATATTTTACTTCAGG
TGTTCGATGATGGACGCTTAACAGATAGTAAAGGGCGTGTAGTCAATTGTAAAAATGCCCTCTTCATCATGACATCAAAT
ATTGGATCTGACCTCTTATTAGAAAAGATGGAGCAAAACAAACAAGGCCTTGCTAAAGACGAAATTATGTTGGTCTTAGA
TCCTGTAATCAAAAAACATTTCCGCCCAGAATTTATTAACCGCTTAGACGATATTCTTCCTTTTGTTCCTCTACGTGAAC
ATGATATGGAAAAAATTGTCGTCATTCAACTGAATTTACTTGCTAAGCGTTTAAAAGATCGAGATGTCGAATTAATGTGG
ACACCTCAAGCATTGGCACACTTAGCCAAAGAAGGATATGATCCTCATTTTGGAGCACGTCCATTAAAAAGGTATATTCA
GCAAGAAGTTATTAATCAGTTATCGACTGCAATCTTGGAAGGTAAAATTCCTCCTCATAGCCATATCAAACTTGAATTGG
AAGGAAACACAATTCGATTTAAATCGTTTGCTGGAGGAAAAAATTAA

Protein sequence :
MNQNFTDHVAEAIQAAFAEAQRLNHTEVTENHLLWAFLKDKEGYFYSLLNGLGTNPQKLFQETENNIHHLPTYSGGGQAP
NPSRSLQSRIVDAQNIAQSWKDTYTSSDHFLISYWKNGGDPFASWKKKTTISLEKLEEQIKKIRGDRHMDSPSSESNLQA
LEKYCKNLTDLARQGKLDPVIGRDEEIRRTMQVLCRRTKNNPMLIGDPGVGKTAIAEGLAQRIVQQDIPDSLKNKQLLAL
DMGSLIAGTKYRGEFEERLKGILQDIEKSEGQIILFIDEVHTLIGAGATDGAMDAANLLKPALARGILHCIGATTLNEYQ
KYIEKDAALERRFQLVLVNEPTIEDSIAILRGLRERYEIYHGVHITESAIHAAVLLSSRYITDRRLPDKAIDLIDESASL
IRMQLGSRPLPIDNKERELAGLIVEQEAMKRESTPLAKNEVEKLEGRIAQIKEELKILREQWDQEKKIIESLKEKKDKLE
KLRFEEEAAERKADYNRVAELRYNLIPQLQKEIEEAQTQLNNKPNRLLQEEVDESLIAQIVSKWTGIPVHKMLEGEAERL
LHLENELEKRVVGQEIAVSAVSEAIRRSRSGLSDPNRPMGVFLFLGPTGVGKTELAKALAFQLFNQDEALIRLDMSEYME
KHTVSKLIGSPPGYIGYEEGGQLTEALRRRPYAVVLFDEIEKAHPDVFNILLQVFDDGRLTDSKGRVVNCKNALFIMTSN
IGSDLLLEKMEQNKQGLAKDEIMLVLDPVIKKHFRPEFINRLDDILPFVPLREHDMEKIVVIQLNLLAKRLKDRDVELMW
TPQALAHLAKEGYDPHFGARPLKRYIQQEVINQLSTAILEGKIPPHSHIKLELEGNTIRFKSFAGGKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 9e-133 45
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-105 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_007727.1 endopeptidase Clp ATP-binding chain VFG2076 Protein 5e-112 44