Gene Information

Name : pyk (pc1636)
Accession : YP_008635.1
Strain : Candidatus Protochlamydia amoebophila UWE25
Genome accession: NC_005861
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1956411 - 1958207 bp
Length : 1797 bp
Strand : -
Note : strongly similar to pyruvate kinase

DNA sequence :
ATGGCATTAATTAGAACAAAAATTGTTTGTACAATAGGACCTGCTTGCAATTCCTTAGAGAAAATTATTGAGTTAATAAA
CGTAGGAATGAACGTTGCAAGGTTGAATTTTAGTCATGGAACTCAAGAAGAACATTTAAGGACAATTAATCTTTTAAAAG
AAGCGAGATGTCAACTTAACTTACCTTTAGCCATCATGTTAGATACAAAAGGGCCAGAAATACGGCTAGGAAAAATTCGA
GATGGACAAATTTTTTTAACGGTAGGTCAAAAATGGCGGTTAGTGAAAAAGGAGGTTTTAGGAGATGAAAGTCAGGTTTC
TATTTTTCCTCTCAATATTTTAGATCAACTTCCTGTTGGGACAACAATTTTATTTGATGATGGGTATATTGCCTCACGCG
TGATTGAAAATTCATCCGAAGGTGTGCTTGTTGAAATTAATAACAGCGGGATGATTCGTTCAAGTAAAGGAGTTAATATT
CCCAATACAAGCCTAAATTTGCCTGCTGTCACCGAAAAAGACATTGACGATATTCGTTTTGGATGTAGCCAGGATATTGA
CTTGATTGCTGCTTCCTTTGTTCGTTCTGCAGAACATGTCTTGGAGATTAAGCGTTTATTAGCTGATGAAAAAAAAACTG
ATATTCTAGTTATTGCAAAAATTGAAAATAGTGAAGGGGTGCAAAATTTTGATAGCATTGTCCAAGCAGCAGACGGAATC
ATGATAGCAAGAGGAGATTTAGGGGTTGAAGTTCCTTTAAGCCATGTTCCTAGATTGCAGAAAATGATGATCCGTAAAAG
TTATTTGGCAGGCAAGCCAGTTGTGACAGCAACGCAGATGTTAGAATCAATGATCAATAATCCTAGACCAACTCGTGCAG
AAACATCTGATGTAGCAAATGCGATTTATGATAGTACATCTGCTATCATGCTTTCAGGAGAAACAGCAATTGGTCGTTAT
CCTGTTGAGACGGTTAATGTGATGCGAAGTATCGTAGAAGAGGCTGAAGCTGATTTCAACTACAGTACTTTTTTTGATCA
ACATGCCCCTTTAGTTTATCATGATGTTCCCTCTGCTGTGACTTTAGCTACTGTAAAAACAGCTTACAGTTCTAGCGCTA
AAGCTATTTTTGCTTTTACTAAAGCAGGAACAACGGCACGACTTTTATCAAGACTTAGGCCTAAAATGCCTATTATTGCG
ATGACAGCAAAAGAAAAAATTTTTCATCAGTTGGCATTTAATTGGGGAGTTATTCCTTTTTTAAGTGAACCTTGTAACTC
TTTAGATAAAAGTTTAAAAAAAATCAGTGATTTCGCCCTTGGAAGTCAACACGTCAGCTATGGAGATTTGGTTGTGATTA
CTGCAGGAACTCCTTTTGGATTTTCAGGAACGACCAATATGATGATCGTTGAAAATATTGGAGATGTTTTGGTAAGAGGG
CACTCTGGATATGGTATACGTGTGCATGGGAACGTAGTAATAGTTCTTGCTCCTCAGTCTAAAGCTCCTTATGCGGTCAA
AGATCAGGTACTTGTGATTGCCAAATGCGATGAGAGTTATTTATCTTTAATGAAGGAAGCTTCTGCTATTATTTTACAGA
ACCATATCAATGATTTTGCGTCTGAAAAATACGCGAAGAAGATTGCTCTGAGTTTAGGTAAGCCTATTCTTCTTCGAGCT
GATGCGGCATGTCAAATTTTAAAAGAAGGACAGCTTGTTACTCTCGATCCTGAAAAAGCCCTTGTTTACAAAGGAGTTGT
TTTGGACCAATTGTTGGCGAGTGGAGAATTTTCATGA

Protein sequence :
MALIRTKIVCTIGPACNSLEKIIELINVGMNVARLNFSHGTQEEHLRTINLLKEARCQLNLPLAIMLDTKGPEIRLGKIR
DGQIFLTVGQKWRLVKKEVLGDESQVSIFPLNILDQLPVGTTILFDDGYIASRVIENSSEGVLVEINNSGMIRSSKGVNI
PNTSLNLPAVTEKDIDDIRFGCSQDIDLIAASFVRSAEHVLEIKRLLADEKKTDILVIAKIENSEGVQNFDSIVQAADGI
MIARGDLGVEVPLSHVPRLQKMMIRKSYLAGKPVVTATQMLESMINNPRPTRAETSDVANAIYDSTSAIMLSGETAIGRY
PVETVNVMRSIVEEAEADFNYSTFFDQHAPLVYHDVPSAVTLATVKTAYSSSAKAIFAFTKAGTTARLLSRLRPKMPIIA
MTAKEKIFHQLAFNWGVIPFLSEPCNSLDKSLKKISDFALGSQHVSYGDLVVITAGTPFGFSGTTNMMIVENIGDVLVRG
HSGYGIRVHGNVVIVLAPQSKAPYAVKDQVLVIAKCDESYLSLMKEASAIILQNHINDFASEKYAKKIALSLGKPILLRA
DAACQILKEGQLVTLDPEKALVYKGVVLDQLLASGEFS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-70 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-70 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-70 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-69 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_008635.1 pyruvate kinase VFG0479 Protein 3e-70 43