Gene Information

Name : tkt (pc1514)
Accession : YP_008513.1
Strain : Candidatus Protochlamydia amoebophila UWE25
Genome accession: NC_005861
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1810308 - 1812341 bp
Length : 2034 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
TTGGTGAAAAATATGAGCAGCCATCTTCAAGTTTCAGTGCCTCAACCTCTCGATTCTGAGCAAAAGCAAATCATGAAACA
AATAGCAAATACCATTCGAGGTCTTTCGATGGATGCTGTTCAAAAAGCAGATTCAGGTCATCCAGGGCTTCCAATGGGAT
GTGCTGAACTTGGTGCATACTTATATGGTTATTATCTTAAGCAAAATCCCAAAAATTCTAAATGGCTCAATCGTGATCGT
TTTATTTTATCTGCTGGACACGGATCTATGTGGTTATATTCTTGTCTACACTTAGCTGGTTACAAAATCACGTTGGAAGA
CATCAAAAATTTCAGGCAGCTTCATTCCCCAACTCCAGGCCATCCAGAATCATTTATGACGGATGGTGTGGAAACAACGA
CGGGGCCTTTAGGGCAAGGTGTAGGTAATGCTGTCGGTCAAGCACTTGGATTTAAAATTCTTGGAGAAAAATTTAACACA
GAAAAGCATCCCATTTTTAATAATAAAGTTTATGTGTTAATGGGTGATGGTTGTGTAATGGAAGGGATTTCTTCAGAAGT
ATCTTCATTAGCTGGTCATTTAAAATTGAATAATTTGGTTGCTATTTATGATGCGAATCACGTTTCTTTAGATGGACCGT
TAGCAGAAAGTTCTTCAGAAGATACTAAAACTCGTTATAAGGCTTATGGTTGGGATGTATTTGAAATAGATGGAAACGAT
ATTGAAGCTATTGATACTGTATTTTCTCAAATTCGACACTATCAAGAAAAGCCTTGTTTAGTTATAGCTCATACTATTAT
TGGGAAAGGAGCCCCGAATAAAGGGGGGACTTATAAAGCCCATGGATCACCTCTTGGAGTAGAAGAAATTAAAGCAGCTA
AAGATGAACTGGGCATTCCTCAAGAAGATTTCTATGTTCCTCAAGCTGTCATCAACTACTTTCAAAATAAGCTTGTTTCC
GATGCAAAAGAACAAAATGAGTGGAAGCAAATATTTGAAGAATGGGCAAAAGAAAATCCTTCTAAATTCCAAGAATTAGA
AGTCATGCTACATCACAAACTTCCCGACGATTTCGAGCAAAAGCTTCAGCATCTGATGATTAAAGCTCCAATTTCCGGAC
GTAAAGCTTCTCAAGAAGTTCTCAATAGTTTAGCAGATATGATTCCTCAATTATACGGAGGGTCAGCTGATTTATCTTCA
TCCGATATGACAATGTTAAAGAAGTTTTCTTTAATTGCTCCTAACGAATTTCATGGACGCAATATTAAGTTCGGTGTACG
AGAATTTGGGATGGCGACAATAGCGACTGGTCTTTATCAAACTGGAATGATTCTTCCATTTGTAGGAACTTTTTTAACTT
TTTCTGATTATATGCGTAATGCAATTCGCTTGGCGGCTTTACAACATGCACAAGTTTTTTATCAATTTACCCATGATTCT
ATTTTCTTAGGGGAAGATGGGCCTACTCACCAACCTGTTGAACATTATGCAGCTTTAAGAGCTATTCCTCAACTACAAGT
AATCCGCCCAGCAGATAGTTATGAAGTAAAAATGTCTTGGATTGCAGCTTTGCAATATAAAGGCCCTACGGCTTTGATTT
TGTCTCGACAGAATTTACCTGATTTAGCTGGGACAAACATTCCTTATGTTGAAGGAATGGGAAGAGGGGCTTATATCGTA
AAAAAAGAAAAAGGAAAGGCTGACTTTACTTTAGTTGCAACTGGCTCGGAATTGAGTTTAGCGATGAACGTAGCAAATGA
ATTAGAAAAACTTGGTAAAAATGTCCGGGTTATTTCTATGCCTTGCTGGGCTTTATTTGAAAAGCAACCTATAGATTATA
AAGAAAGTCTGTTTGGTGGAGATATTGGTAAAAGGGTCAGTATTGAAGCTGGTGTTGACCTTGGATGGCATAAATACATT
GGCCGTGATGGTATTGCAATTTGTATGGAACATTTTGGAGCCTCAGCTCCTGCGGGTGTATTAGCAAAAGAATTTGGTTT
TACCGTTGAGGCTATACTTGAACGTATTTTATAG

Protein sequence :
MVKNMSSHLQVSVPQPLDSEQKQIMKQIANTIRGLSMDAVQKADSGHPGLPMGCAELGAYLYGYYLKQNPKNSKWLNRDR
FILSAGHGSMWLYSCLHLAGYKITLEDIKNFRQLHSPTPGHPESFMTDGVETTTGPLGQGVGNAVGQALGFKILGEKFNT
EKHPIFNNKVYVLMGDGCVMEGISSEVSSLAGHLKLNNLVAIYDANHVSLDGPLAESSSEDTKTRYKAYGWDVFEIDGND
IEAIDTVFSQIRHYQEKPCLVIAHTIIGKGAPNKGGTYKAHGSPLGVEEIKAAKDELGIPQEDFYVPQAVINYFQNKLVS
DAKEQNEWKQIFEEWAKENPSKFQELEVMLHHKLPDDFEQKLQHLMIKAPISGRKASQEVLNSLADMIPQLYGGSADLSS
SDMTMLKKFSLIAPNEFHGRNIKFGVREFGMATIATGLYQTGMILPFVGTFLTFSDYMRNAIRLAALQHAQVFYQFTHDS
IFLGEDGPTHQPVEHYAALRAIPQLQVIRPADSYEVKMSWIAALQYKGPTALILSRQNLPDLAGTNIPYVEGMGRGAYIV
KKEKGKADFTLVATGSELSLAMNVANELEKLGKNVRVISMPCWALFEKQPIDYKESLFGGDIGKRVSIEAGVDLGWHKYI
GRDGIAICMEHFGASAPAGVLAKEFGFTVEAILERIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-128 46
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 5e-127 45