Gene Information

Name : lpdA (pc0151)
Accession : YP_007150.1
Strain : Candidatus Protochlamydia amoebophila UWE25
Genome accession: NC_005861
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 227479 - 228888 bp
Length : 1410 bp
Strand : +
Note : E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGATGGAAATAAAAAAATTCGATGTGGCTGTTCTTGGAGGAGGCCCTGGCGGCTATCCAGCTGCGATTCGAGCAGCACA
ACGAGGTAAATCTGTTGCATTGATTGAAGCCAAAGAATTGGGTGGTACTTGTTTAAATAGGGGGTGTATTCCTTCAAAAG
CTCTAATTGCTGGAGCAGAAGTTGTTGATCGCATCCATGAAGCGAAAGAATTTGGAATTCATGTGGGTGAAGTTAATATC
GATTATGCTCAACTTGCTTTCCATAAAGACCGAGTGATTGAACGGATGCGTAAAGGCTTAGAAGGGCTTATGGCAACTAA
TAAAATTACTGTTTTTAAAGGATTTGGACAATTTATTTCCCCTCGAGAAATTAAAATCAAAGGTCAGGATAATACAAGTA
TTACCGCCGATCAAATTATCATCGCGACAGGATCAGAACCGCGTAATATTTCAGCTTTCCCATTTGACTATGAACGCATT
CATGACTCTACCTCACTGCTAGCCATGAAAACTCTTCCTGAAAAACTTATTATCGTTGGAGGGGGAGTCATTGGCTGTGA
ATTTGCCTCTCTTTATGCCACTCTTGGTGTCCATGTGACAATCTTAGAATTGTTGCCACGTTTAATTTCGTCTGAGGCTA
TTGAAGTATCACAAGCATTGACAAAAGCATTTATTAAGCGAGGTATTCAAGTAGAAACAGGGGTAAAAGTTCAAAAAATT
GAACAAGTTGAGATGGGAATACAAGTTCAAGTAGAAGAAGGAAAACATTACGTTGCTGACTGTTGTTTAGTCGCAGTAGG
TCGTTCTCTCAATACTAAAAACATTGGACTTGACAAAGCAGGTATTTTAGTTCAAGAAAATGGGATGATTGCTGTCAATG
ATAAAATGCAAACAAACGTTGATGGTATTTACGCGGTAGGGGACATTGCATCGAAGTGGTGGTTAGCTCACGTTGCTTCT
CACCAAGGCCTTATAGCAGCAGACCAAATTTGTGGAAAAAGTAGTCGTATGTATTATCACGCGATTCCTTCCGTAATCTT
TACTCATCCTGAAATCGCAACAGTCGGATTATCACTTGAAGAAGCGACGAAAAGAGGATATAAAGCTAAGTTGGCGAGCT
TTCCTTTTCAGGCGCTTGGAAAATCTCAAGCTGCTTTACAGGCAGAAGGATTTGCCCAAATTGTTGTCGAAGAAAAATCA
GGACAGATTCTTGGCGCTCAAGTTGTTGGTTATGAAGCCTCTGTAATGATTGCAGAAATGACTCTCGCTATTGCGAACGA
ATTGACCGTGGAATGTGTGGCAGAAACCATCCATGCCCATCCTACTCTACCGGAAGCTTGGCTAGAATCAGCACTACTAG
GGGAAGGTTTACCCTTGCATTTACCCCCTAAAACGCAAAAAAAGGGATAA

Protein sequence :
MMEIKKFDVAVLGGGPGGYPAAIRAAQRGKSVALIEAKELGGTCLNRGCIPSKALIAGAEVVDRIHEAKEFGIHVGEVNI
DYAQLAFHKDRVIERMRKGLEGLMATNKITVFKGFGQFISPREIKIKGQDNTSITADQIIIATGSEPRNISAFPFDYERI
HDSTSLLAMKTLPEKLIIVGGGVIGCEFASLYATLGVHVTILELLPRLISSEAIEVSQALTKAFIKRGIQVETGVKVQKI
EQVEMGIQVQVEEGKHYVADCCLVAVGRSLNTKNIGLDKAGILVQENGMIAVNDKMQTNVDGIYAVGDIASKWWLAHVAS
HQGLIAADQICGKSSRMYYHAIPSVIFTHPEIATVGLSLEEATKRGYKAKLASFPFQALGKSQAALQAEGFAQIVVEEKS
GQILGAQVVGYEASVMIAEMTLAIANELTVECVAETIHAHPTLPEAWLESALLGEGLPLHLPPKTQKKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 1e-72 42