Gene Information

Name : serS (pc1488)
Accession : YP_008487.2
Strain : Candidatus Protochlamydia amoebophila UWE25
Genome accession: NC_005861
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1770921 - 1772201 bp
Length : 1281 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATATTCGCTTAATCCGTAAAGATCGTTTTGCAGTTGAGAAACAGTTAAAAACGAAAGATCCGCAAATTGATCT
TACTAATATTTGTCACCTCGATCATTCTATTCGCGAAGCTAAAACAAAAGTTGAAACTCTCAAGGCAAAACGTAATGAGA
TTTCTCAGAAAATCGGAGAAATGAAACGGGCTAACCAAGATACTTTTTCTTTAATGAATGAAGTAGCAGGATTTGGAACA
GAAATTCATTTTTTGGATAACCAAATTAAAGAATGGGAAGAACAATTTAATTATGAGTTATCTAGCTTACCTAATCTTCC
CATGGAAGATATTAAAATCTCTCAAGATCCTAAAGAAAATGTTGTTATCAAAGAGTTTGGACAAAAACCTATTTTTTCTT
TTCCATTCAAAAATCACGTAGAACTTAATGAAAAATTAAATTTATTTGATTTTAAGCGTGGAGCTAAAATTTCTGGAACA
GGCTGGCCCGTTTATCGAGCCATGGGAGCACGTCTAGAATGGGCCCTCATCCAATATATGATCGAAATTCACGTCAAAAA
TGGATTTACACAATGGATCCCTCCCCTTCTTGTTAGAAAAAATACTGTGTTTGGATCTGGACAATTACCTAAATTTGAAA
GTCAACAATTTAAAATTCAAGATGAGGATTATCATCTTTATTTAATTCCTACAGCCGAAGTTCCTCTTAATGGATTGCAT
ATGGATGAGATTATTCCTCAAGAAGAGCTCAGTCTAAAATATGTAGCCTACACCCCTTGTTTTAGGCGTGAAGCAGGAGC
AGCAGGATCGCAAGAACGTGGTCTAATTAGAATGCATCAATTTAATAAAGTCGAAATGTTTTGCTTTACAAAACCGGAGG
AAAGCGCACAAGTATTCAATCAAATGATGGATAGCGCAGAGGAAATTTTGCAAGGCTTAGAACTCCATTATCGTAATGCT
TTACTAGTAACTGGGGACATGTCTTTCGCTGCAGCGCGCACAATAGACATTGAAGTTTGGTTACCCGGACAAAACAGATA
TTATGAAGTCTCTTCTGTATCTAATTGTACAGATTATCAATCCCGTCGTTCTAATACACGTTTTAGACGCGAAGACGGAA
AGTTAGATTTTGTTCATACCCTTAATGGTTCTGGATTAGCGACTTCTCGATTAATGGTTGCTTTATTAGAAAATAATCAG
CGGGAAGATGGCTCTGTTTGTATTCCTAATGTCTTACAACGCTATTTAAACGGACAAAGCACATTGAATCCCACAATTTG
A

Protein sequence :
MIDIRLIRKDRFAVEKQLKTKDPQIDLTNICHLDHSIREAKTKVETLKAKRNEISQKIGEMKRANQDTFSLMNEVAGFGT
EIHFLDNQIKEWEEQFNYELSSLPNLPMEDIKISQDPKENVVIKEFGQKPIFSFPFKNHVELNEKLNLFDFKRGAKISGT
GWPVYRAMGARLEWALIQYMIEIHVKNGFTQWIPPLLVRKNTVFGSGQLPKFESQQFKIQDEDYHLYLIPTAEVPLNGLH
MDEIIPQEELSLKYVAYTPCFRREAGAAGSQERGLIRMHQFNKVEMFCFTKPEESAQVFNQMMDSAEEILQGLELHYRNA
LLVTGDMSFAAARTIDIEVWLPGQNRYYEVSSVSNCTDYQSRRSNTRFRREDGKLDFVHTLNGSGLATSRLMVALLENNQ
REDGSVCIPNVLQRYLNGQSTLNPTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 8e-81 43