Gene Information

Name : sctN (pc1397)
Accession : YP_008396.1
Strain : Candidatus Protochlamydia amoebophila UWE25
Genome accession: NC_005861
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 1673399 - 1674763 bp
Length : 1365 bp
Strand : +
Note : strongly similar to type III secretion pathway protein sctN

DNA sequence : 
TTGTCCTTATTTTCTATCTACTATTGTTTCCAACTAAGGGTAAATTTCATGTTTTTTAATGATCAAATTGACAAACTTCT
GGATGATCTAGATGAACTTCAACTTACGACGGTGAATGGCCGCATTACCGAAATTGTTGGAATGTTAATCAAAGCTGTGG
TGCCTCAAGTAAAAATTGGGGAAGTTTGTTTAATCAAAAGAGCAGGTGACCCTTTACGCGCAGAAGTGGTGGGTTTTACA
AAAGACGAAGTCCTTCTTTCTCCTTTAGGAGAAATGACTGGTATCGGCCCCTCTTCTGAAGTCATTCCCACTCATCTTCC
TTTACACATCAAAGTCGGCCCTCAATTGCTTGGGAGAATTTTAAATGGTTTAGGAGAACCCTTAGACGAAGAAACCAAAG
GTCCTTTAATCTTAGAAGAGACCTATCCTGTTATTCAAGCTCCTCCTGACCCTGTCAAAAGAATGCCTATTCATAACCCT
ATTTCCGTTGGAATAAGGGCTATTGACGGCGTATTAACTACAGGCCTCGGACAAAGAGTAGGGATTTTTGCTGCTGCAGG
TGGTGGTAAATCAACATTACTTGGAATGATTGCTCGCAATGCAGTCGCAGATGTCAATGTAATCAGTTTAATTGGGGAGC
GAGGGCGAGAACTCAGAGAATTTATTGAAAAGGATTTAGGTCCCGAAGGACTAAAAAGATCTGTCCTTGTGGTCTCGACC
TCTGACCAAGCCTCCCAGCTTCGTCTCAATGCAGCTTACGTTGGTACTGCGATTGCTGAATATTTTAGAGATCAAGGTAA
ATCTGTCATCTTAATGATGGATTCGGTGACGAGATTTGCAAGAGCTCTGCGTGAAGTAGGCTTAGCAGCAGGCGAACCTC
CGGCAAGAGCTGGTTATACTCCTTCAGTCTTTTCAACGCTTCCTAAACTATTGGAAAGAGCGGGAAATTCTGATAAAGGG
AGTATTACAGCTTTTTATACTATCTTAGTGGCTGGAGATGATATGAATGAACCCGTTGCTGATGAAGTACGCTCTATTCT
GGATGGTCACATTATTTTATCTAGTGAACTTGCACGTCAATATCATTATCCCGCCATTGATGTTCTCTCCTCTGCAAGTC
GTGTCATGAATGCCATTGTTCCCAAAGAACACTTGCAATTAGTTGGTAAACTTAAAGAAGTTTTAGCTAATTATAAAAAA
AACGAGCTATTAATTAAAATTGGCGAATACAAAAGAGGGGCGGATAAAGCAGGAGATTTTGCCATAGACTATATCGAAAA
AGTTTTAAAATTTCTCAAACAAGGTGTCGACGAAAAATGCTCATTTCAAGAGACTGTCCAACTCCTGAAATCTCTCTTCA
GATAA

Protein sequence : 
MSLFSIYYCFQLRVNFMFFNDQIDKLLDDLDELQLTTVNGRITEIVGMLIKAVVPQVKIGEVCLIKRAGDPLRAEVVGFT
KDEVLLSPLGEMTGIGPSSEVIPTHLPLHIKVGPQLLGRILNGLGEPLDEETKGPLILEETYPVIQAPPDPVKRMPIHNP
ISVGIRAIDGVLTTGLGQRVGIFAAAGGGKSTLLGMIARNAVADVNVISLIGERGRELREFIEKDLGPEGLKRSVLVVST
SDQASQLRLNAAYVGTAIAEYFRDQGKSVILMMDSVTRFARALREVGLAAGEPPARAGYTPSVFSTLPKLLERAGNSDKG
SITAFYTILVAGDDMNEPVADEVRSILDGHIILSSELARQYHYPAIDVLSSASRVMNAIVPKEHLQLVGKLKEVLANYKK
NELLIKIGEYKRGADKAGDFAIDYIEKVLKFLKQGVDEKCSFQETVQLLKSLFR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-114 58
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-106 55
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-106 55
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-105 54
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-105 54
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 5e-105 54
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 5e-105 54
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-105 54
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-103 53
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-103 53
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-90 52
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 9e-90 52
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 9e-90 52
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-90 52
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-90 52
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-88 52
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-91 51
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-91 51
escN AAC38383.1 EscN Virulence LEE Protein 3e-89 50
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-89 50
escN AAC31513.1 L0034 Virulence LEE Protein 2e-89 50
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-89 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 5e-90 50
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 8e-90 50
escN YP_003223475.1 translocator EscN Virulence LEE Protein 5e-90 50
escN AAK26715.1 EscN Virulence LEE Protein 4e-90 50
escN AAL57542.1 EscN Virulence LEE Protein 4e-90 50
escN YP_003236088.1 translocator EscN Virulence LEE Protein 5e-89 50
escN CAI43874.1 EscN protein Virulence LEE Protein 4e-90 50
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-89 50
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-88 50
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 8e-79 49
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-90 49
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-79 48
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-81 48
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-93 48
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 4e-88 48
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-88 48
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-88 48
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-81 47
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-81 47
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 5e-75 46
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 4e-76 46
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 4e-76 46
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 5e-75 45
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-74 45
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-72 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-72 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-72 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-72 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sctN YP_008396.1 type III secretion system ATPase VFG2144 Protein 1e-148 72
sctN YP_008396.1 type III secretion system ATPase VFG0048 Protein 9e-121 61
sctN YP_008396.1 type III secretion system ATPase VFG0390 Protein 4e-116 60
sctN YP_008396.1 type III secretion system ATPase VFG0192 Protein 2e-115 57
sctN YP_008396.1 type III secretion system ATPase VFG0515 Protein 2e-90 52
sctN YP_008396.1 type III secretion system ATPase VFG0730 Protein 2e-89 50
sctN YP_008396.1 type III secretion system ATPase VFG0812 Protein 1e-89 50
sctN YP_008396.1 type III secretion system ATPase VFG1254 Protein 3e-87 49
sctN YP_008396.1 type III secretion system ATPase VFG1778 Protein 2e-76 47
sctN YP_008396.1 type III secretion system ATPase VFG2331 Protein 1e-80 46
sctN YP_008396.1 type III secretion system ATPase VFG2499 Protein 1e-82 46
sctN YP_008396.1 type III secretion system ATPase VFG1008 Protein 2e-70 45
sctN YP_008396.1 type III secretion system ATPase VFG2459 Protein 2e-78 45
sctN YP_008396.1 type III secretion system ATPase VFG0555 Protein 9e-73 43