Gene Information

Name : mutS (pc1221)
Accession : YP_008220.1
Strain : Candidatus Protochlamydia amoebophila UWE25
Genome accession: NC_005861
Putative virulence/resistance : Virulence
Product : DNA mismatch repair protein MutS
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0249
EC number : -
Position : 1452876 - 1455452 bp
Length : 2577 bp
Strand : +
Note : This protein performs the mismatch recognition step during the DNA repair process

DNA sequence :
TTGTTTATTTTTCAATTAAAAATAAGTTTATTTATGTCTGATTTTGAACAACATTCCCTTGATGAAAGTAAAATTTCACC
CATGATGATGCAGTGGCACGCCTGTAAAAAAATGGCGGGCGATGCCATTTTATTTTTTCGGATGGGTGATTTTTATGAAG
CTTTTTATGAAGACGCTCATCTGCTATCTAAGGAGTTGGAGCTGACATTGACTAAACGGCAAGAAATTCCCATGAGTGGA
ATTCCTTTTCATACAAGTGAAGGATATATCGATAAACTTGTCGCTAAAGGATTTCGAGTTGCCATTGCAGAACAAATAGA
AGATCCTAAAAAAACTAAAGGCTTAGTCAAGCGCGAAGTTGTTCGTGTTGTGTCTCCTGGAACAGTTATTAACTCCTCTC
TTCTTTCCGACAAAAACAATAATTTTTTTGCTGCCTTAGTAAAAGTGGGGCAAATTTTTGGATTAGCTTTTTTAGATTTG
ACGACTGGTGAATATTGGGTGAGTGAATTTACGCAAGAAAGAGAACTTTTAAATGAACTTTATCGTTTGCACCCTGCTGA
ATTTTTAACTTCTGAAAAATTCAAAGAAAAACATGCTTCTTTGTTTGAAGAAATGCAACAAACATATTCTTTTTTAGTCA
ATACATTAGAAGACTGGCAATTTGAGCATCAACAAGCACATGATTTCCTTATTAATCATTTCAAGGTTCAACGCTTAGAT
GGTTTTGGACTAAGCGGAATGGTTGCAGCTATCAATGCCGCAGGAGCTTTATTAAATTATTTACAAGAAACACTGTGTCT
ACCAATCCAACATATTCAAAGCATTCGTTGCTATTCTTCTTCCCAGTTTATGATGTTAGATCGAATGACACAGCGTAATC
TGGAACTAACGCATTCTCTACAAGACGGAAGTAGACGTCATACATTGCTAGGTGTCATTGATCAAACGCAGACTCCTATG
GGCGCTCGGCTCATGCATCATTGGGTTAAGCAACCTCTTTTAAAAGTTTCTGAGATTCATCAAAGGCAAAATGGAATCCA
AGCTCTATTAAATCACGAACACATTGTAGATCAATTACAAAATCTATTCCTTCAAATTAAAGATATTGAACGCTTGATGA
TGAAAGTCAGTGCTTGCTACGCTACGCCTCGGGACCTTATAGCTCTTCATTTTTCTTTTAAGCCCATTGCATTTATTAAA
TCTCTTTTGTTAAACATTCCTTCAGAATGGATAAATGAGCACGCACAAAAACTTGATCCTCTATCTAAAATGAATGCATT
AATATCCAATGCAATCGTAGAAGAGCCGCCTCTAAGACTTGGTGAAGGGAAAACGTTCCGACAAGGTTTTCATCGTGAAT
TAGATGAATTGCGAGAAATCAGTCATGACAGTAAAGCTTGGATGGCTCGTTACCAAACTCAAATCAGAGAAGAAACCGGT
ATTAAAACCCTGAAAGTAGGTTTTAATAAAATGTTTGGTTATTTTATCGAAGTCAGTCGTGGTCAAATAGATAAAATGCC
TGATCACTTTATACGTCGACAAACCCTTGTTAATGCTGAACGGTATATCACACCTGAGTTAAAAGAATATGAAAGCAAAG
TCTTAACAGCGGAAGAACGCATCAACTCTATTGAAAGTGAACTTTTTCACCAACTTCGTTTAGAAGTTGCTTCATATACT
AAAAATGTATTAGAAGTCGCTCAAGCATTAGCTAAAATTGATTGTTTAATATCTTTAACCAATGTAGCAAAAAAGTATTG
CTACACATGTCCTGTCATTGATGACAGCTCCATTCTTGTGATCGAAGAAGGAAGGCATCCAGTAATCGAGACAGTGTGCC
GGCATGAAAAATTTATTCCCAATGACACGTATTTAGATGATCAAGCTAATCGATTGCTCTTAATCACAGGCCCTAACATG
GCAGGAAAATCGACATATCTGAGACAAGTAGCTTTAATTGTCATTTTAGCTCAAATAGGTTCTTTCGTTCCAGCAGCTAA
AGCTCACATAGGAATTATCGATAAAGTCTTTACACGAATAGGTGCTAGTGATGATTTATCTAGAGGACAGTCAACTTTTA
TGGTTGAAATGACTGAAACGGCAAATATTTTAAACAATGCCACTTCTCAATCTCTCGTTATTTTAGATGAAATCGGTCGG
GGAACAAGTACATATGACGGCATATCAATTGCTTGGTCTGTGGCAGAATATCTTCTAACAACAGAAAAAAGGATGGCTAA
AACATTATTTGCAACTCATTACTGGGAACTTACAAAATTAGAAGAGAAGGTTCCAGGTGCTGTTAATTACAACGTTGCTG
TTCATGAAGCGGACGATCACATTACATTTCTAAGAAAAATCATCAAAGGAGGAACTGACAAAAGCTATGGAATCCACGTT
GCTCGCCTAGCTGGGCTTCCACAAGCCGTTTTAAACCGTTCTAAAGAAATTTTAGAACATTTGGAAGAAAATGCGAATCG
TAAGAGCGCTTTTGAGCCTACCCGTTCAAAAAAGAGTATGGTTTCTAAAGTAAAAGTTCCTTCAACTGACTTTCAATTGA
ACTTATTTCAATCATAA

Protein sequence :
MFIFQLKISLFMSDFEQHSLDESKISPMMMQWHACKKMAGDAILFFRMGDFYEAFYEDAHLLSKELELTLTKRQEIPMSG
IPFHTSEGYIDKLVAKGFRVAIAEQIEDPKKTKGLVKREVVRVVSPGTVINSSLLSDKNNNFFAALVKVGQIFGLAFLDL
TTGEYWVSEFTQERELLNELYRLHPAEFLTSEKFKEKHASLFEEMQQTYSFLVNTLEDWQFEHQQAHDFLINHFKVQRLD
GFGLSGMVAAINAAGALLNYLQETLCLPIQHIQSIRCYSSSQFMMLDRMTQRNLELTHSLQDGSRRHTLLGVIDQTQTPM
GARLMHHWVKQPLLKVSEIHQRQNGIQALLNHEHIVDQLQNLFLQIKDIERLMMKVSACYATPRDLIALHFSFKPIAFIK
SLLLNIPSEWINEHAQKLDPLSKMNALISNAIVEEPPLRLGEGKTFRQGFHRELDELREISHDSKAWMARYQTQIREETG
IKTLKVGFNKMFGYFIEVSRGQIDKMPDHFIRRQTLVNAERYITPELKEYESKVLTAEERINSIESELFHQLRLEVASYT
KNVLEVAQALAKIDCLISLTNVAKKYCYTCPVIDDSSILVIEEGRHPVIETVCRHEKFIPNDTYLDDQANRLLLITGPNM
AGKSTYLRQVALIVILAQIGSFVPAAKAHIGIIDKVFTRIGASDDLSRGQSTFMVEMTETANILNNATSQSLVILDEIGR
GTSTYDGISIAWSVAEYLLTTEKRMAKTLFATHYWELTKLEEKVPGAVNYNVAVHEADDHITFLRKIIKGGTDKSYGIHV
ARLAGLPQAVLNRSKEILEHLEENANRKSAFEPTRSKKSMVSKVKVPSTDFQLNLFQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mutS AAA80578.1 DNA mismatch repair protein Virulence SPI-1 Protein 8e-132 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mutS YP_008220.1 DNA mismatch repair protein MutS VFG0562 Protein 5e-146 43