Gene Information

Name : leuS (pc1047)
Accession : YP_008046.1
Strain : Candidatus Protochlamydia amoebophila UWE25
Genome accession: NC_005861
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1244786 - 1247323 bp
Length : 2538 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAAATACGATCATCAACAAATTGAAGCAAAATGGCAAAAGTTTTGGCAAGATAATCAAACCTATCGTTCAGACGATAA
TTTTCAGAAACCCAAATACTATGTTTTAGATATGTTCCCTTATCCTTCGGGAGCTGGATTACACGTAGGTCATGTTGTAG
GGTATACCGCAACCGATATTATTGCCCGTTATATGCGAACTAAAGGCTATAATGTGATGCATCCAATGGGATGGGATAGT
TTTGGTCTTCCAGCAGAGCAATATGCAATTCGAACAGGAACACATCCTGCCGAATCAACACAAGAAAATATTAATAATTA
TCGTCGCCAACTTCGAGCTCTAGGATTTAGCTATGACTGGAATAGAGAACTGGCAACAAGTGACCCAAATTATTATAAAT
GGACGCAATGGATTTTCACAAAGCTCTATGAAAAAGGGCTGGCCTACGAAGCTGAAATGCTTGTTAATTATTGTCCAGCT
TTGGGAACTGTATTAGCAAATGAAGAAATTGAAAATGGAAAAACAAAAGATGGAGGCCATCCTGTTGAAAGAAGACCTCT
TAAACAATGGATTTTAAAAATTACGGCTTATGCAGATCGTTTGCTTCAAGATTTAGACTTATTAGATTGGCCTGAAAGTT
TAAAAAAATTGCAGATTAATTGGATTGGAAAAAGCGAAGGAGCTTATGTTCAATTTATCGAAAAAACAACCCAAGAAGCT
TTTTCTGTCTTTACAACGAGACCGGATACTTTATTTGGAGTCTCTTATTTAGTTTTAGCTCCCGAGCATCCTTTGGTATC
TCACATTACAGCTTCTAGCCAGCAGCAAGCAGTTCGCGCTTATCAAGCGCAAATAGCAAGTAAAAGTGATTTGGATCGAA
CCGAGCTTAATCGGGATAAAACAGGGGTGTTTACAGGAGCTTATGCAGTCAATCCCGTTAATCATAAGGAAATACCCATT
TGGATTTCTGATTATGTATTGATGAATGTCGGAACAGGGGCTATCATGGCTGTACCCGCTCATGATGAGAGAGATTTTGA
ATTTGCGAAGACTTTTAAACTTCCAATCATTCCTGTCTATGATCCTGTTTGTGAAGAAATAACCATTCGAAATCAAGTCT
TGGCTGGACAGCAATGCTGGCCGGGCCATGGTATTTGTGTCAATAGTGCTTGTGGCGATCTCTCCCTCAATGGTTTAAAT
CTAGACCAAGCAAAGAAAATTGTTATCAACTGGTTGGAAATTAACCATAAAGGAAAGTCTGCCACGACTTATAAATTACG
CGATTGGTTGTTTTCTCGCCAGCGGTACTGGGGAGAGCCTTTTCCTTTACTCAAATTTGAGGACGGATCGGTTCGACTTC
TTGATGAAGATGAACTTCCCCTATGTCCACCTGCAATTACAAATTACAAACCCACTGGCGATGGAAAAGGGCCATTAACG
CAAATTAAAGAATGGGTAGAGATCATTGATACAAAAACAGGAAAAAAAGCCTTTAGAGATACAAACATTATGCCACAATG
GGCAGGATCTTGCTGGTATTATCTTCGTTTTTGCGACCCACACAATACAGAAAAAGCATTTTCTCCAGAAAAAGAAAAAT
ATTGGTTACCTGTTGATTTGTATATAGGTGGGGTAGAACATGCTGTCTTACACCTTCTTTATGCTCGATTTTGGCATAAG
GTTCTGTATGATTGCGGTTACGTGCATACCCTAGAACCTTTTCAAACTCTTCGTAATCAAGGCCTCGTTGTTGCCCGTTC
CTATCAAAATAAGATGCGTGTGTATGTTGAACCTCGCTATGTGGAACAAAGAGATGGCAAATATTTTGATAGCCGGACAG
GAGAAGAGTTAACTAGCCAAATTGATAAAATGTCTAAAAGTAAACTCAATGGGGAAAGTCCGGATGAAATCATCCAAGAA
TATGGAGCTGACGCACTTCGTTTATATGAAATGTTTATGGGCCCTCTTGAAAAAGAAAAAGTTTGGAATACAGATGCTGT
GTCAGGAACAAGGCGGTTTCTTAATCGATTTTATGAAATGGCATTTTCAGACAAAGTCACCAACGAAACATCTGAAGAAG
GGCTTAAATTGGGACACCGTCTTGTTCATAGCGTAATGAAAGATATGGAATTGCTTCAGTTTAACACGGCAATTGCTAAA
ATGATGGAATTTATAAATGAATTTACTAAGTTGGTTACTTATCCAAAACAAGTTATTCAAATGGCAACTCAAGTATTAGC
TCCCTTTGCACCTCATCTTGCAGAGGAAGTGTGGGAACATTTAAAATGTGAAGGATCTCTTTCTTTTACTCCATATCCGC
AAGTGGAAGAAAAATACTTACAAGAGAATGTAATTACTTATGTTGTGCAAATTAATGGTAAGGTAAGAGGTCGATTTGAT
TTACCTAAAGATCAAACGCAAGAAAATGTCTTAGAAGCGGCTAAAAATAACCCTCATATCCAGCAATACATTAACAAAAA
AGAAATTGGGAAAGTTGTTTTTGTTCCTAATAAACTCTTAAGCATTGTTTTAAGATAA

Protein sequence :
MKYDHQQIEAKWQKFWQDNQTYRSDDNFQKPKYYVLDMFPYPSGAGLHVGHVVGYTATDIIARYMRTKGYNVMHPMGWDS
FGLPAEQYAIRTGTHPAESTQENINNYRRQLRALGFSYDWNRELATSDPNYYKWTQWIFTKLYEKGLAYEAEMLVNYCPA
LGTVLANEEIENGKTKDGGHPVERRPLKQWILKITAYADRLLQDLDLLDWPESLKKLQINWIGKSEGAYVQFIEKTTQEA
FSVFTTRPDTLFGVSYLVLAPEHPLVSHITASSQQQAVRAYQAQIASKSDLDRTELNRDKTGVFTGAYAVNPVNHKEIPI
WISDYVLMNVGTGAIMAVPAHDERDFEFAKTFKLPIIPVYDPVCEEITIRNQVLAGQQCWPGHGICVNSACGDLSLNGLN
LDQAKKIVINWLEINHKGKSATTYKLRDWLFSRQRYWGEPFPLLKFEDGSVRLLDEDELPLCPPAITNYKPTGDGKGPLT
QIKEWVEIIDTKTGKKAFRDTNIMPQWAGSCWYYLRFCDPHNTEKAFSPEKEKYWLPVDLYIGGVEHAVLHLLYARFWHK
VLYDCGYVHTLEPFQTLRNQGLVVARSYQNKMRVYVEPRYVEQRDGKYFDSRTGEELTSQIDKMSKSKLNGESPDEIIQE
YGADALRLYEMFMGPLEKEKVWNTDAVSGTRRFLNRFYEMAFSDKVTNETSEEGLKLGHRLVHSVMKDMELLQFNTAIAK
MMEFINEFTKLVTYPKQVIQMATQVLAPFAPHLAEEVWEHLKCEGSLSFTPYPQVEEKYLQENVITYVVQINGKVRGRFD
LPKDQTQENVLEAAKNNPHIQQYINKKEIGKVVFVPNKLLSIVLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 54