Gene Information

Name : TTC0789 (TTC0789)
Accession : YP_004762.1
Strain : Thermus thermophilus HB27
Genome accession: NC_005835
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.16.1.1
Position : 771676 - 773049 bp
Length : 1374 bp
Strand : -
Note : -

DNA sequence :
ATGACCTACGACCTCCTCATCGTGGGCTCGGGCTCCGCCGGGGTGGCGGCGGCCCTGGAGGCGAGCGCCCTCGGGGCCAA
GGCGGCCGTGGTGGAGGCGGGGGTTTTGGGGGGGACCTGCGTCAACGTGGGGTGCGTGCCCTCCAAGTACCTCCTCCGGG
CGGCCGACGCCTTCCACCGGGCGCGCCACCCCGCCTTCCCCGGCCTCCGCACGGAGGCCCTGGGGGTGGACTGGAAAGCC
CTCCTCGCGGGCAAGGAGGGCCTGATCGCGGCCCTCAGGAAGGAGAAGTACCAGGAGGTCCTGGAGGCGGCCGGGGTTCC
CGTGCTCCGGGGGAGGGCCCGCTTCCTGGACGGGGAAAGGATGGAGGTAGAGGGGCGGGAGGTCTTGGCCGGGCGGTACC
TCCTCGCCACCGGGGCGAGGCCCTTCCTTCCGCCCATCCCCGGCCTCCGGGAGAGCGCGCCCTGGACCTACCTCGAGGCC
CTCTCCGCCCCCGCCCTTCCCGAAAGCCTCCTGGTGGTGGGGGGTGGGCCCATCGGGCTTGAGCTCGCCCAGGCCTTCGC
CAGGCTTGGGAGCCGGGTGACGGTCCTCGAGGCCCTGCCCGAGGTCCTGCCCCAGGAGGACCGGGAGCTTGCCCGGCTCC
TCCGGGGCTACCTGGAGGAGGAGGGCCTTAGGGTCCACACCGGGGTCCGGGTGGAGGCCGTGGCCCGGGAAGGGGCCTTC
CGCGTCCGGACCGACCGGGGGGTTTTTGAGGCGGAGAGGCTCCTCGTGGCCACGGGGAGGAGGCCGGACCTGGAAGGGCT
CGGCCTGGAGCGGGCGGGCGTGGAGCGGGACGAGCGGGGCTTCCTCCGGCTGGACCCCAGCCTGCGCACCACCAACCCCC
GGGTCTACGCCGCCGGGGACGCGGCGGGGCTTCCCCAGTTCGTCTACGTGGCCGCCCAGTCGGGCAGGGTGGCGGCCCGC
AACGCCTTGGGGGTAAAGGCGCCCCTGGACCTCGCCGCCCTCCCCCGGGTCACCTTCACCGACCCCGCCCTGGCCGCGGT
GGGCCTCACGGAGGAGGAGGCGAGGAGGCGGTACGGCGCGGGGGTGCGGGCGGCCACCCTTCCCCTTTCCCAGGTGCCCA
AGGCCCTCACCGTCCGCGATGCCCGGGGGGCCTTCAAGATCGTGGTGGACGAAGAGGGCACGGTCCTCGGCCTCCACGTC
CTGGCTCACGAGGCGGGGGACGTCATCCAGGAGGGCATCCTGGCGGTGAAGTACGGCCTCGGCTACCGGGACCTCATAGA
CACCTTCCACCCCTACCTGACCCTGGCCGAGGGGATAAGGCTCGTGGCCCAGGCCCTGGACGCCGATCCCAAAAAGCTTT
CCTGCTGCGCCTGA

Protein sequence :
MTYDLLIVGSGSAGVAAALEASALGAKAAVVEAGVLGGTCVNVGCVPSKYLLRAADAFHRARHPAFPGLRTEALGVDWKA
LLAGKEGLIAALRKEKYQEVLEAAGVPVLRGRARFLDGERMEVEGREVLAGRYLLATGARPFLPPIPGLRESAPWTYLEA
LSAPALPESLLVVGGGPIGLELAQAFARLGSRVTVLEALPEVLPQEDRELARLLRGYLEEEGLRVHTGVRVEAVAREGAF
RVRTDRGVFEAERLLVATGRRPDLEGLGLERAGVERDERGFLRLDPSLRTTNPRVYAAGDAAGLPQFVYVAAQSGRVAAR
NALGVKAPLDLAALPRVTFTDPALAAVGLTEEEARRRYGAGVRAATLPLSQVPKALTVRDARGAFKIVVDEEGTVLGLHV
LAHEAGDVIQEGILAVKYGLGYRDLIDTFHPYLTLAEGIRLVAQALDADPKKLSCCA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 2e-62 44
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 3e-64 42
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 4e-64 42
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 2e-62 42
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 1e-62 42
merA AFG30120.1 MerA Not tested PAGI-2 Protein 1e-62 42
merA ABQ57371.1 MerA Not tested SGI1 Protein 5e-65 42
merA AGK07021.1 MerA Not tested SGI1 Protein 5e-65 42
merA AGK07079.1 MerA Not tested SGI1 Protein 5e-65 42
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 2e-63 42
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 1e-63 42
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 1e-63 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TTC0789 YP_004762.1 mercuric reductase BAC0653 Protein 1e-63 43
TTC0789 YP_004762.1 mercuric reductase BAC0651 Protein 2e-64 42
TTC0789 YP_004762.1 mercuric reductase BAC0650 Protein 8e-60 42
TTC0789 YP_004762.1 mercuric reductase BAC0652 Protein 2e-65 41