Gene Information

Name : TTC0593 (TTC0593)
Accession : YP_004568.1
Strain : Thermus thermophilus HB27
Genome accession: NC_005835
Putative virulence/resistance : Virulence
Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 575467 - 577014 bp
Length : 1548 bp
Strand : +
Note : -

DNA sequence :
ATGAGGTACGCGGACCGGGTGGCCGGGATTTCCTGGGAGACGATTGAGGAGGTGCGCCGGCGCCTCAAGGAAAGGCCCGC
CCTCCACTTCATCGCCGGGGAGTTCGTTCCCTCGGAAAGCGGGGAGACCTTCCCCTCCTTGGACCCCGCCACGAACGAGG
TCTTGGGCGTGGCGGCGAGGGGCGGGGAGAGGGAGGTGGACCGGGCGGCCAAGGCGGCCCACGAGGCCTTCCAAAGGTGG
AGCCGCACCAAGGCCAAGGAGAGGAAGCGCTACCTCTTGAGGATCGCCGAGCTCATAGAGAAGCACGCGGACGAGCTCGC
CGTGATGGAGTGCCTGGACGCGGGGCAGGTCTTAAGGATCGTCCGGGCCCAGGTGGCCCGGGCGGCGGAGAACTTCGCCT
TCTACGCCGAGTACGCCGAGCACGCCATGGAGGACCGGACCTTCCCCGTGGACCGGGACTGGCTCTACTACACCGTGCGG
GTTCCCGCGGGGCCCGTGGGGATCATCACCCCCTGGAACGCCCCCCTAATGCTCTCCACTTGGCGCATCGCCCCCGCCTT
GGCCTTTGGGAACACCGTGGTCCTGAAGCCCGCGGAGTGGAGCCCCTTCACCGCCACGAAGCTCGCGGAGATCCTAAAGG
AGGCGGACCTCCCCCCGGGGGTCTTCAACCTGGTCCAGGGCTTTGGCGAGGAGGCGGGGGCGGCCCTGGTGGCCCACCCC
CTCGTCCCCCTCCTCACCCTCACCGGGGAGACGGAGACGGGGAAGATCGTCATGCGCAACGCCGCAGACCACCTCAAGCG
CCTCTCCCCGGAGCTCGGCGGCAAAAGCCCCGCCCTGGTCTTCGCCGACGCCGACTTGGAGAGGGCCCTGGACGCCGTGG
TCTTCCAGATCTTCTCCTTCAACGGGGAAAGGTGCACGGCAAGCTCCAGGCTCCTCGTGGAGGAGAAGATCTTTGAGGAC
TTCGTGGGGAAGGTGGTGGAAAGGGCCAGGGCCATCCGGGTGGGCCACCCCCTGGACCCCGAGACCGAGGTGGGGCCCCT
GATCCACCCCGAGCACCTCCAAAGGGTCCTGGGCTACGTGGAGGCGGGGAAGCGGGAAGGGGCGAGGCTCCTCGTGGGCG
GGGAGCGGGCCAAGACCTCCTTCCGGGGGGAGGACCTCTCCCGGGGGAACTACCTCCTCCCCACGGTTTTCGTGGGGGAG
AACCACATGAAAATCGCCCAGGAGGAGATCTTCGGGCCCGTCCTCGTGGCCATCCCCTTCAAGGACGAGGAGGAGGCCCT
AAGGAAGGCGAACGACACCAAGTACGGCCTCGCCGCCTACGTCTTCACCCGGGATCTGGAAAGGGCCCACAGGCTCGCCT
TGGAGCTCGAGGCGGGGATGGTCTACCTGAACAGCCACAACGTCCGCCACCTGCCCACGCCCTTCGGCGGGGTGAAGGGA
AGCGGGGACCGGAGGGAGGGCGGCACCTACGCCCTGGACTTCTACACCGACCTCAAGACCATTGCCCTTCCCCTCCGCCC
CCCGCACGTGCCCAAGTTCGGGAAGTAA

Protein sequence :
MRYADRVAGISWETIEEVRRRLKERPALHFIAGEFVPSESGETFPSLDPATNEVLGVAARGGEREVDRAAKAAHEAFQRW
SRTKAKERKRYLLRIAELIEKHADELAVMECLDAGQVLRIVRAQVARAAENFAFYAEYAEHAMEDRTFPVDRDWLYYTVR
VPAGPVGIITPWNAPLMLSTWRIAPALAFGNTVVLKPAEWSPFTATKLAEILKEADLPPGVFNLVQGFGEEAGAALVAHP
LVPLLTLTGETETGKIVMRNAADHLKRLSPELGGKSPALVFADADLERALDAVVFQIFSFNGERCTASSRLLVEEKIFED
FVGKVVERARAIRVGHPLDPETEVGPLIHPEHLQRVLGYVEAGKREGARLLVGGERAKTSFRGEDLSRGNYLLPTVFVGE
NHMKIAQEEIFGPVLVAIPFKDEEEALRKANDTKYGLAAYVFTRDLERAHRLALELEAGMVYLNSHNVRHLPTPFGGVKG
SGDRREGGTYALDFYTDLKTIALPLRPPHVPKFGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 5e-89 47
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-65 44
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-62 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 5e-64 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 5e-64 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 5e-64 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TTC0593 YP_004568.1 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase VFG0082 Protein 1e-62 42