Gene Information

Name : smpB (TTC0546)
Accession : YP_004521.1
Strain : Thermus thermophilus HB27
Genome accession: NC_005835
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 532455 - 532889 bp
Length : 435 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCCCCCGTGCTGGAGAACCGCCGCGCGCGGCACGACTACGAGATCCTGGAAACCTACGAGGCGGGCATCGCCCTCAA
AGGGACCGAGGTGAAGTCCCTGAGGGCGGGGAAGGTGGACTTCACGGGAAGCTTCGCCAGGTTTGAGGACGGCGAGCTTT
ACCTGGAAAACCTCTACATCGCTCCCTACGAGAAGGGCTCCTACGCCAACGTGGACCCGAGGAGGAAGCGGAAGCTCCTC
CTGCACAAGCACGAGCTTAGGCGGCTTCTCGGCAAGGTGGAGCAGAAGGGCCTCACCCTGGTCCCCCTCAAGATCTACTT
CAACGAGCGGGGGTACGCCAAGGTCCTCCTGGGCCTCGCCCGGGGGAAGAAGGCCTACGAGAAGCGGCGCGAGGACAAGA
AGGAGGCGGTGCGCCGCGCCTTGGAGGAGCTATGA

Protein sequence :
MAPVLENRRARHDYEILETYEAGIALKGTEVKSLRAGKVDFTGSFARFEDGELYLENLYIAPYEKGSYANVDPRRKRKLL
LHKHELRRLLGKVEQKGLTLVPLKIYFNERGYAKVLLGLARGKKAYEKRREDKKEAVRRALEEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-21 53
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-21 48
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 1e-13 42