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Name : leuS (TTC1825) Accession : YP_005794.1 Strain : Thermus thermophilus HB27 Genome accession: NC_005835 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 1731471 - 1734107 bp Length : 2637 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGGAGAAGTACAACCCGCACGCCATTGAGGCCAAGTGGCAGCGCTTCTGGGAGGAGAAGGGGTTCATGAAGGCCAAGGA CCTCCCGGGGGGCCGGGGGAAGCAGTACGTCCTCGTCATGTTCCCCTACCCCTCGGGGGACCTGCACATGGGCCACCTGA AGAACTACACCATGGGGGACGTCCTGGCCCGCTTCCGCCGGATGCAGGGCTACGAGGTCCTCCACCCCATGGGCTGGGAC GCTTTTGGCCTTCCGGCGGAGAACGCCGCCCTGAAGTTCGGCGTCCACCCCAAGGACTGGACCTACGCGAACATCCGCCA GGCCAAGGAGAGCCTCCGGCTCATGGGCATCCTTTACGACTGGGACCGGGAGGTCACCACCTGCGAGCCCGAGTACTACC GCTGGAACCAGTGGATCTTCCTCAAGATGTGGGAAAAGGGCCTGGCCTACCGGGCGAAGGGCCTCGTCAACTGGTGCCCC AAGTGCCAGACGGTCCTCGCCAACGAGCAGGTGGTGGAGGGGCGGTGCTGGCGGCACGAGGACACCCCCGTGGAGAAGCG GGAGCTGGAGCAGTGGTACCTGCGCATCACCGCCTACGCCGAGAGGCTTCTTAAGGACCTCGAGGGCCTCAACTGGCCCG AGAAGGTCAAGGCCATGCAAAGGGCCTGGATTGGCCGCTCCGAGGGGGCGGAGATCCTCTTCCCCGTGGAGGGGAAGGAG GTGAGGATCCCCGTCTTCACCACCCGCCCCGACACCCTCTTCGGAGCCACCTTCCTCGTGCTCGCCCCGGAGCACCCCTT GACCCTGGAGCTCGCCGCCCCGGAGAAGCGGGAGGAGGTCCTGGCCTACGTGGAGGCCGCCAAGCGCAAGACGGAGATTG AGCGCCAGGCGGAAGGCAGGGAGAAGACCGGGGTCTTCCTGGGGGCCTACGCCCTAAACCCCGCCACGGGGGAGAGGATT CCCATCTGGACTGCGGACTACGTGCTCTTTGGCTACGGCACCGGGGCCATCATGGCCGTCCCTGCCCACGACCAGAGGGA CTACGAGTTCGCCAGGAAGTTCGGCCTTCCCATCAAGAAGGTGATTGAGCGGCCCGGCGAGCCCCTCCCCGAGCCCCTGG AAAGGGCCTACGAGGAGCCCGGGATCATGGTGAACTCCGGGCCCTTTGACGGGACGGAAAGCGAGGAGGGGAAGCGGAAG GTCATCGCCTGGCTGGAGGAGAAGGGCCTGGGCAAGGGCCGGGTCACCTACCGCCTCCGGGACTGGCTCATAAGCCGCCA GCGCTACTGGGGGACCCCCATCCCCATGGTCCACTGCGAGGCCTGCGGGGTGGTCCCCGTCCCCGAGGAGGAGCTTCCCG TGCTCCTTCCCGACCTCAAGGACGTGGAGGACATCCGCCCCAAGGGGAAGAGCCCCCTGGAGGCCCACCCCGAGTTCTAC GAGACCACCTGCCCCAAGTGCGGCGGCCCCGCCAAGCGGGACACGGACACCATGGACACCTTCTTTGACTCCAGCTGGTA CTACCTGCGCTACACCGACCCCCACAACGACCGCCTCCCCTTTGACCCCGAGAAGGCGAACGCCTGGATGCCCGTGGACC AGTACATCGGCGGGGTGGAGCACGCGGTGCTTCACCTCCTCTACAGCCGCTTCTTCACCAAGTTTCTCCACGACCTGGGG ATGGTGAAGGTGGAGGAGCCCTTCCAGGGCCTCTTCACCCAGGGCATGGTCCTCGCCTGGACGGACTTTGGCCCCGTGGA GGTGGAAGGAAGCGTGGTGCGCCTCCCCGAGCCCACCCGCATCCGGCTGGAGATCCCAGAAAGCGCGCTTTCCCTGGAGG ACGTGAGGAAGATGGGGGCCGAGCTCCGCCCCCACGAGGACGGCACCCTCCACCTCTGGAAGCCCGCCGTCATGAGCAAG TCCAAGGGCAACGGGGTCATGGTGGGGCCCTTCGTGAAGGAGCAGGGGGCGGACATCGCCCGCATCACCATCCTCTTCGC CGCGCCCCCGGAGAACGAGATGGTCTGGACCGAGGAGGGGGTCCAGGGGGCCTGGCGCTTCCTGAACCGCATCTACCGGC GGGTGGCCGAGGACCGGGAGGCCCTTTTGGAGACGAGCGGGGTCTTCCAGGCCGAGGCTTTAGAGGGGAAGGACCGGGAG CTTTACGGGAAGCTGCACGAGACCCTGAAGAAGGTCACGGAGGACCTCGAGGCCCTCCGCTTCAACACCGCCATCGCCGC CCTCATGGAGTTCCTGAACGCCCTCTACGAGTACCGCAAGGACCGCCCCGTCACCCCGGTCTACCGCACCGCCATTCGCT ACTACCTGCAGATGCTCTTCCCCTTCGCCCCCCACCTCGCCGAGGAGCTTTGGCACTGGTTCTGGCCCGATAGCCTCTTT GAGGCGGGCTGGCCCGAGCTGGACGAGAAGGCCCTGGAGAAGGACGTGGTGGAGGTGGCCGTCCAGGTGAACGGGCGGGT GCGGGGGACGATCCACATCCCCAAGGACGCCCCCCTGGAGGTGGCGCGGGCCGAGGCCCTTAAGGTGCGAAACGTAAGGG CCCACCTCGAGGGCAAGGAGGTGGTGAAGGAGATCTACGTCCCGGGGAAGATCCTCAACCTGGTAGTGCGGGGGTAG Protein sequence : MEKYNPHAIEAKWQRFWEEKGFMKAKDLPGGRGKQYVLVMFPYPSGDLHMGHLKNYTMGDVLARFRRMQGYEVLHPMGWD AFGLPAENAALKFGVHPKDWTYANIRQAKESLRLMGILYDWDREVTTCEPEYYRWNQWIFLKMWEKGLAYRAKGLVNWCP KCQTVLANEQVVEGRCWRHEDTPVEKRELEQWYLRITAYAERLLKDLEGLNWPEKVKAMQRAWIGRSEGAEILFPVEGKE VRIPVFTTRPDTLFGATFLVLAPEHPLTLELAAPEKREEVLAYVEAAKRKTEIERQAEGREKTGVFLGAYALNPATGERI PIWTADYVLFGYGTGAIMAVPAHDQRDYEFARKFGLPIKKVIERPGEPLPEPLERAYEEPGIMVNSGPFDGTESEEGKRK VIAWLEEKGLGKGRVTYRLRDWLISRQRYWGTPIPMVHCEACGVVPVPEEELPVLLPDLKDVEDIRPKGKSPLEAHPEFY ETTCPKCGGPAKRDTDTMDTFFDSSWYYLRYTDPHNDRLPFDPEKANAWMPVDQYIGGVEHAVLHLLYSRFFTKFLHDLG MVKVEEPFQGLFTQGMVLAWTDFGPVEVEGSVVRLPEPTRIRLEIPESALSLEDVRKMGAELRPHEDGTLHLWKPAVMSK SKGNGVMVGPFVKEQGADIARITILFAAPPENEMVWTEEGVQGAWRFLNRIYRRVAEDREALLETSGVFQAEALEGKDRE LYGKLHETLKKVTEDLEALRFNTAIAALMEFLNALYEYRKDRPVTPVYRTAIRYYLQMLFPFAPHLAEELWHWFWPDSLF EAGWPELDEKALEKDVVEVAVQVNGRVRGTIHIPKDAPLEVARAEALKVRNVRAHLEGKEVVKEIYVPGKILNLVVRG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 1e-156 | 44 |
