Gene Information

Name : clpA (TTC0174)
Accession : YP_004149.1
Strain : Thermus thermophilus HB27
Genome accession: NC_005835
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpA
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 155470 - 157680 bp
Length : 2211 bp
Strand : -
Note : -

DNA sequence :
ATGAACCGATACGACGACCGCGCCAGGCTGGTCTTTCACTACGCAAGAGAGGAGGGGAGCCGCTTAGGCCACTCCATGAT
CGGCCCGGAGCACCTCCTCCTGGGCCTGATGCGCGAGGGGGGTACGGCGGCCCGCATCCTCCAGGAGTACGGCGCGAGCC
TCGAGGCCATGCGCCGCATGGTGGAGGAGCTGGTGGGCCGGGGGGAGGGCGGGCGCACCGGGGAGCCCCCCGCCATCACC
CCGAGGGCGAGGCGGGTCATGGAGCTCGCCAGCGCCGAGGCCCGCAACATGGGCTCCCCCGTCATCGGCACGGAGCACAT
CCTCCTCGGCATCATCCGGGAGGGGGACGGGATCGCCTACCGCATCCTCAGCCACTTCGCCAAGGACGTGGACGCCATCC
GCTGGAGGGTCCTGGCCATGGCCGAGGGCCGCGAGCGGGAAAAGCCCGTGAACACCCCCTTCCTGGACGAGTACGGCCGC
GACCTCACCAAGGAGGCCCGGGAAGGGAAGCTGGACCCGGTGATCGGCCGCCAGGAGGAGATCAACCGGGTGATCCAGAT
CCTCGCCCGGCGCACCAAGAACAACCCCGTGCTCATCGGCGACCCCGGGGTGGGCAAGACGGCCATCGTGGAGGGCCTGG
CCCAGGCCATCGTGGAGGGCCGGGTCCCCCCCATCCTCAAGGGGGCCCGGGTGGTGGCCATTGACCTCGCCGGAGTGGTG
GCGGGGACCAAGTACCGGGGCGAGTTTGAGGAGCGCCTGCGGCAGATCATTGAGGAGCTCAAGAACGCCAAGGTCATCGC
CTTCATTGACGAGCTTCACACCCTGATCGGGGCGGGCGGGGCCGAGGGCACCCTGGACGCCGCCAACATCCTCAAGCCCG
CCCTGGCCCGCGGGGAGATCCAGGTGATCGGGGCCACCACCACCGGGGAGTACCACCGCTACATAGAGAAGGACGCGGCC
CTGGAGCGGCGCTTCCAGCCGGTGATCGTCCTCGAGCCCTCCCCCGAGGAAACCCTGGAGATCCTCAAGGGCCTCCGCCC
CCGCTACGAGGCCCACCACGGGGTGATCATCCCCGACGAGATCCTGGAGCTTGCGGTGAAGATCGGGATCCGCTCGCTTC
CCGGGCGCAACTTCCCCGACAAGGCCATTGACCTCATTGACGAGGCGGCCTCGAGGGTGCGCCTCAACGCCTCCTTGGGC
CTCCCCGTGGCGGAGGAAGAGGACGGCACCCCCATCGTCACCCGGGAGGACGTGGAAGCGGTGGTGGACTCCTGGGGCGG
GGTCTACGTGGACGACAAGGACGACGAGAAACTCATGCGCCTGGAGGAGGAGCTCAGGAAGCGGGTGGTGGGCCAGGAGG
AGGCCATCCGCGCCCTGGCGAACGCCCTCCGCCGGGCCCGGGTGGGGCTTGGGGGAAGGACCCGGGTGGCGGCGAGCTTC
CTCTTCGTGGGGCAAAGCGGCGTGGGCAAGACCCAGCTCGCCAAGGCCCTGGCCGAGGTCCTCTTCGGCTCGGAGAGGGC
CCTCATCCGCTTTGACATGTCCGAGTTCCAGGAGCCCCACTCCATCTCCAAGCTCATCGGGGCCCCGCCGGGCTATGTGG
GCTACGAGCAGGGGGGCCGCCTCACCGAGGCCGTGCGCCGCCAACCCTTCAGCGTGGTCCTCCTGGACGAGATTGAGAAG
GCCCACCCCGACATCTACAACACCTTCCTCCAGGTGCTGGACGAGGGCCGCCTCACGGACGGCATGGGCCGCACCGTGGA
CTTCCGCCGGGTCATCCTCATCATGACCTCCAACACCGGCTACAACGTGGGCCCCGCCATCGGCTTCACCTCCAAGGAGG
TGGACACGGAGTCCCCCCTGAAGGCCCTCTTCACCCCCGAGTTTCTGGACCGGCTGGACGAGGTCATCCGCTTCCGACCC
CTCACGGAGGAGGAGCTGGTGCGGGTGGCCGAGATGATGCTGGAGGACATCCGCAAGGAGCTCCAGGCCCGGGACGTCCA
GGTGAGCTTCGCCCCCGAATTGGCCCGCTTCCTGGTGGACCAGGCTCCCAAGACGGGGAGCGCCCGCGCCCTGCGGAGCG
TCCTAAGGGAGCGCATAGAGGACCCCTTGGCCGTCGCCCTCCTGCGGAAGCCCACGGGCCGGATCCACGTGAGCGTGGAG
GGAGGTCAGGTGGCCTTCCACGAGGTGGAGGGGGAAGAGCTCCTCGTCTAG

Protein sequence :
MNRYDDRARLVFHYAREEGSRLGHSMIGPEHLLLGLMREGGTAARILQEYGASLEAMRRMVEELVGRGEGGRTGEPPAIT
PRARRVMELASAEARNMGSPVIGTEHILLGIIREGDGIAYRILSHFAKDVDAIRWRVLAMAEGREREKPVNTPFLDEYGR
DLTKEAREGKLDPVIGRQEEINRVIQILARRTKNNPVLIGDPGVGKTAIVEGLAQAIVEGRVPPILKGARVVAIDLAGVV
AGTKYRGEFEERLRQIIEELKNAKVIAFIDELHTLIGAGGAEGTLDAANILKPALARGEIQVIGATTTGEYHRYIEKDAA
LERRFQPVIVLEPSPEETLEILKGLRPRYEAHHGVIIPDEILELAVKIGIRSLPGRNFPDKAIDLIDEAASRVRLNASLG
LPVAEEEDGTPIVTREDVEAVVDSWGGVYVDDKDDEKLMRLEEELRKRVVGQEEAIRALANALRRARVGLGGRTRVAASF
LFVGQSGVGKTQLAKALAEVLFGSERALIRFDMSEFQEPHSISKLIGAPPGYVGYEQGGRLTEAVRRQPFSVVLLDEIEK
AHPDIYNTFLQVLDEGRLTDGMGRTVDFRRVILIMTSNTGYNVGPAIGFTSKEVDTESPLKALFTPEFLDRLDEVIRFRP
LTEEELVRVAEMMLEDIRKELQARDVQVSFAPELARFLVDQAPKTGSARALRSVLRERIEDPLAVALLRKPTGRIHVSVE
GGQVAFHEVEGEELLV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-128 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpA YP_004149.1 ATP-dependent Clp protease ATP-binding subunit ClpA VFG0080 Protein 5e-122 49
clpA YP_004149.1 ATP-dependent Clp protease ATP-binding subunit ClpA VFG0079 Protein 6e-131 45